Search PubMed⌕ Search

Biomedical subjects

T Naito

Publications and source records attributed to T Naito.

At least 307 records · Page 17Linked to original sources
PubMed1981

Successful pregnancy in a patient undergoing chronic hemodialysis.

A 29-year-old woman who had been undergoing regular hemodialysis for 4 years became pregnant, and a male infant weighing 1320 g was delivered by cesarean section. The infant has grown uneventfully and shows no abnormalities at present. This is the first case in Japan and the eighth reported case to date (1979) in which a patient undergoing chronic hemodialysis became pregnant and was delivered of a live infant.

Female↗
PubMed1980

Bu-2313, a new antibiotic complex active against anaerobes. III. Semi-synthesis of Bu-2313 A and B, and their analogs.

Analogs of Bu-2313 A and B were prepared by C-acylation of tetramic acid derivatives with the dienoic acid moiety obtained by periodate oxidation of Bu-2313 A or B. The C-acylation proceeded in the presence of a strong base such as potassium t-butoxide, sodium hydride or lithium hydride, whereas the use of triethylamine afforded O-acylated products. The semi-synthetic Bu-2313 analogs exhibited antibacterial spectra similar to the parent antibiotic but none exceeded Bu-2313 B in activity.

Aminoglycosides↗
PubMed1978

Aminoglycoside antibiotics. XII. Effect of N-alkylation in kanamycin antibiotics.

Four N-ethyl derivatives of kanamycin A and five N-ethyl derivatives of kanamycin B were synthesized. The antimicrobial activity of N-ethyl kanamycin derivatives was determined against aminoglycoside-sensitive and resistant organisms. The structure-activity relationship of these compounds is discussed with reference to the activity of N-acyl kanamycin derivatives.

Alkylation↗