Search PubMed⌕ Search

Biomedical subjects

T Myers

Publications and source records attributed to T Myers.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

A system of rhinomanometry in the clinical evaluation of nasal decongestants.

The utility of an anterior rhinomanometric method for the assessment of decongestant drug activity is illustrated with representative clinical data. Controlled studies employing topical nasal spray, nasal inhaler, and oral syrup formulations were conducted under single- or double-blind conditions in patients with allergic or coryzal rhinitis. The method provided an objective means to distinguish active from placebo (vehicle) treatments and to discriminate differences in decongestant activity between two active formulations. Furthermore, objectively determined increases in nasal patency paralleled the patients' subject-ve perception of improved airflow. In conclusion, this rhinomanometric methodology provided objective confirmation of drug activity with orally-administered, inhaled, and topically-applied decongestant drug formulations.

Administration, Intranasal↗
PubMedDate not supplied

Sexual partnering and risk of HIV/STD among Aboriginals.

OBJECTIVE: To examine the contribution of patterns of sexual partnering to the spread of HIV/STD infection between communities. METHODS: 651 randomly selected Aboriginals from 11 reserve communities in Ontario were interviewed. This analysis included those who had sex in the previous 12 months. Descriptive statistics and multivariate analyses identified associations with patterns of sexual partnering. RESULTS: 22% reported having partners from both within and outside the community, 51% from within only, and 27% from outside only. Those with partners from both within and outside were more likely to be male, unmarried, from a remote community, have more sexual partners and perceive that their behaviour placed them at higher risk of HIV/STD infection. They were least likely to perceive their community to be at risk from their behaviour. CONCLUSIONS: Findings suggest that Aboriginal communities are not insulated and that HIV could spread rapidly if introduced.

Adolescent↗
PubMedDate not supplied

The Talking Sex Project: descriptions of the study population and correlates of sexual practices at baseline.

The Talking Sex Project is an HIV risk reduction education project for gay and bisexual men. It was developed to evaluate two types of small discussion groups using a randomized control study design. This paper reports on the baseline measures of knowledge, attitudes and sexual practices. The 612 subjects had a mean age of 32 years, were all English speaking and were relatively highly educated. Bivariate analyses found that younger men, those in a relationship, those reporting bisexual activity and those with higher levels of substance use were significantly more likely to have unprotected anal intercourse. While overall knowledge was not associated with sexual behaviour, a significant relationship was found with knowledge of risk of anal sex. Attitudes, in particular, the belief in the efficacy of condoms and the enjoyment of safer sex were found to have the strongest associations with protected anal intercourse. The paper provides an understanding of some of the factors which may be important to behaviour change and clues for the targeting of programs.

Adolescent↗
PubMedDate not supplied

Decontaminating agents.

Explore the source record for details and available documents.

Anti-Infective Agents↗
PubMedDate not supplied

Prevalence of human immunodeficiency virus and associated risk behaviour in injection drug users in Toronto.

During 1989-90, interviews were conducted with 582 current injection drug users in the City of Toronto, 535 of whom also provided blood and/or saliva for anonymous unlinked HIV antibody testing. The rate of seropositivity identified was 4.3% (95% CI 3-6). The subjects were predominantly male, with a mean age of 28.3. The commonest drug of choice was cocaine (70%). Forty-six percent of the subjects reported using someone else's needle in the preceding six months, 60% of these indicating that they always cleaned it first. Eighty-one percent of those interviewed had been in jail at some time since they began injecting; 25% of these had injected while in custody, and of these 61% had shared injection equipment. Eighty-two percent of the men and 85.4% of the women reported opposite sex partners in the previous six months. Only about 20% of men reported consistent condom use, while 22% of females reported condom use at least 75% of the time.

Adolescent↗
PubMedDate not supplied

Biographical characteristics of injection drug users and behavioural predispositions related to HIV prevention and drug use.

OBJECTIVE: This paper presents a preliminary analysis of the determinants of selected behavioural predispositions toward HIV prevention among injection drug users. METHOD: An exploratory factor analysis was used to group attitudinal, behavioural intention and change statements into five predisposing factors and the correlates with these were examined using general linear regression. RESULTS: The analysis demonstrates that many IDUs have responded to AIDS and highlights the characteristics of those who are predisposed to unsafe practices. Predispositions toward safer sex appear to be contextually determined, and needle-sharing determined by socio-behavioural history. CONCLUSIONS: The data emphasize the need for prevention programs in educational and correctional systems along with community-wide harm reduction and HIV prevention strategies, especially for younger persons. For older drug users, there may be a need for more intensive rehabilitation programs. Some evidence suggest that greater attention be given to the type of drug dependence when focusing programs.

Adolescent↗
PubMedDate not supplied

Condom use and attitudes among heterosexual college students.

INTRODUCTION: This paper analyzes differences between heterosexual male and female college students' behaviour, attitudes and knowledge about condom use. METHOD: A convenience sample of 707 students were recruited at sexual health displays to complete an anonymous questionnaire. RESULTS: Based on reported sexual partners in the previous year, 486 students (51.2% male and 48.8% female) were classified as heterosexual. No significant differences were found between the sexes in reported risk behaviour. Females reported more appropriate condom use techniques than males, and more positive attitudes toward condoms. Males rated sexual enjoyment to be more important. A greater proportion of males than females gave reasons for not using condoms. CONCLUSION: Differences between male and female attitudes and behaviour are important to address in AIDS prevention. Along with an emphasis on the improvement of condom use techniques, it is critical to focus on gender issues of assertiveness, power and trust.

Adolescent↗