Biomedical subjects

T Moum

Publications and source records attributed to T Moum.

61 records · Page 4Linked to original sources

PubMed1992

Genetic and environmental effects on blood pressure in a Norwegian sample.

Systolic (SBP) and diastolic (DBP) blood pressures were measured in a health screening of the adult population in Nord-Trøndelag, Norway. Correlations were computed for 23,936 pairs of spouses, 43,586 pairs of parent and offspring, 19,151 pairs of siblings, 1,251 pairs of grandparents-grandchildren, 1,146 pairs of biological uncles/aunts-nephews/nieces (avuncular), 801 non-biological avuncular pairs, 169 pairs of same-sex twins, and smaller groups of other types of relationships. Spouse correlations of 0.08 and 0.09 were approximately constant or slightly decreasing with marital duration. The correlation values for SBP and DBP were approximately 0.16 for parents-offspring, 0.19 to 0.23 for same-sex siblings with similar values for DZ twins, 0.19 and 0.16 for opposite-sex siblings, 0.52 and 0.43 for MZ twins, and close to zero for most of the second-order relationships. Genetic additive variance was estimated at 0.29 and genetic dominance variance at 0.18 with the best model for SBP. The corresponding estimates from the best models for DBP were 0.29 or lower and 0.22 or lower, the sum not exceeding 0.35. There was evidence of a moderate effect of environmental factors shared by same-sex siblings and twins (for DBP), but no cultural transmission, and whether or not adult relatives live together does not affect familial resemblance for BP. The data did not permit a very precise resolution of the relative magnitude of genetic dominance and sibling effects. The correlation structure did not show sex-specific genetic effects.

Adult↗

PubMed1992

Self-assessed health among Norwegian adults.

Previous research has used self-assessed health as a proxy for 'objective' health rating as an important element in sick role behaviour, as well as a predictor of life satisfaction and mortality. However, several authors have suggested that self-evaluations of health are not only reflections of the underlying medical condition. It has been claimed that personal and social background characteristics such as sex, age, race, and occupational status contribute independently to subjectively appraised health. The present article uses data from a large, nation-wide sample of Norwegian adults (N = 7302) to estimate the relative predictive power of 'medical' variables (number and duration of illness episodes, diagnosis, functional impairment) on the one hand and 'socio-cultural' variables (age, sex, socio-economic status, type of work, income, household composition/life cycle) on the other. It is concluded that when a sufficiently fine-grained array of medical information is available, socio-cultural factors contribute only marginally to self-assessments of health.

Activities of Daily Living↗

PubMed1992

The mitochondrial NADH dehydrogenase subunit 6 (ND6) gene in Murres: relevance to phylogenetic and population studies among birds.

The nucleotide sequences of the mitochondrial ND6 and tRNA(Glu) genes and part of the displacement loop region in two closely related seabird species are presented. A chicken type gene organization in which the tRNA(Glu), ND6, and displacement loop are localized next to each other was found in these species and suggests that this is a conserved feature of avian mitochondrial DNA. The nucleotide and amino acid divergences of ND6 at different taxonomic levels are assessed, and its relevance to phylogenetic studies in birds is discussed.

Amino Acid Sequence↗

PubMed1990

Hypertension labelling, life events and psychological well-being.

Almost all previous studies of the psychological sequelae of hypertension labelling have lacked a prospective, longitudinal design which could allow for causal interpretations. The present study relies on questionnaire data from a hypertension screening carried out on the entire adult population of a medium-sized, Norwegian county (total number of participants = 74977). 'Labelled' individuals, i.e. previously unaware hypertensives (N = 173), false positives (N = 233), and patients in need of continued BP control (N = 474) have been followed up after 1-3 years, and comparisons are made with aware hypertensives (N = 206), patients previously treated for hypertension (N = 118), and a random sample of normotensives (N = 2326). 'Pre-labelling', baseline measures of subjective well-being had been carried out on all comparison groups in connection with the screening. Changes in psychological well-being are not significantly related to labelling or BP-status. However, there is a deterioration in psychological well-being among participants who have been subjected to one or more negative life events/stresses (other than labelling) in the preceding 12 months.

Adaptation, Psychological↗

PubMed1990

Inter-doctor variation in sickness certification.

Do doctor-related factors influence the duration of episodes of sickness certification? This problem was studied in an analysis of 2,999 persons certified sick by 107 general practitioners in Buskerud county, Norway, during a 4-week period in 1985. Doctors' attitudes toward sickness certification were measured by composing an index based on 12 statements (Likert scale), "weighed" by principal component analysis. Doctors' sickness certification practice was measured by duration of each episode of sickness certification. The analysis revealed no association between doctors' attitudes toward sickness certification and the duration of the episodes. Cox regression analysis showed, however, that the duration was significantly longer in patients of the oldest doctors, while it was shorter in patients of specialists in general practice and of GPs working part-time as industrial medical officers.

Adult↗

PubMedDate not supplied

Use of minor tranquilizers among Norwegian physicians. A nation-wide comparative study.

The use of minor tranquilizers (hypnotics and anxiolytics) during the last month before a questionnaire was answered was studied in a postal survey of a nation-wide representative sample of Norwegian physicians (n = 1467), aged 25 to 69 years. The response rate was 73%. A total of 12.2% of the physicians had used minor tranquilizers in the past month, one third of these on a daily or weekly basis. There was no gender difference. High age, high mental distress, and working outside the hospital was identified as risk factors for drug use. Compared to a representative sample of subjects from the general population with the same age and education level, (The Nord-Trøndelag Health Survey), more male physicians than males in the comparison sample had used minor tranquilizers in the past month, also when controlled for subjective well-being. However, the physicians had used the drugs more sporadic. When self-prescription of minor tranquilizers was studied in a different sample of 1024 Norwegian physicians, it was found that 72.6% of the physicians had self-prescribed the drugs. There was no gender difference in self-prescribing.

Adult↗

PubMedDate not supplied

The norwegian version of the psoriasis disability index--a validation and reliability study.

OBJECTIVE: The aim of this study was to translate the Psoriasis Disability Index (PDI) into Norwegian and validate it in a Norwegian setting. The PDI is a measure that was developed to assess the impact of psoriasis on the patient's life. METHODS: Two hundred and eighty-two patients with psoriasis were included in the study (80% outpatients, and 20% hospitalized). RESULTS: Face and content validity were assessed as satisfactory. The PDI seems to capture issues of importance to patients. The results indicate that the PDI does not capture a unidimensional concept. A factor analysis (principal component with orthogonal rotation) resulted in three factors (physical, social, and hygienic) that were substantially different. All three factors had satisfactory internal consistency. Altogether they explained 58% of the variance. In addition, there were differing patterns of correlations with external criteria, such as dimensions of SF-36, as well as with sex, age, and education. CONCLUSIONS: The PDI has been found to have acceptable reliability in this study. However, further validation is necessary to estimate the sensitivity to change.

Journal Article↗