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Biomedical subjects

T Moreau

Publications and source records attributed to T Moreau.

At least 145 records · Page 8Linked to original sources
PubMed1981

[Stage I malignant melanoma of the skin. Prognostic value of thickness and level (author's transl)].

In a retrospective study of 95 patients seen between 1950 and 1978, the outcome of malignant melanoma levels III, IV and V of Clark's classification was reviewed. Patients with lentigo malignant melanoma were excluded. The overall survival rate was 63% at 5 years and 48% at 10 years. For the whole population of patients significant differences in survival rate were associated with level (p = 0,00002), thickness (less than 2 mm or greater than or equal to 2 mm; p less than 0.0,0001) and histological type (p = 0,02). The significance of prognostic variables taken separately was calculated by the Breslow method and was found to be: p = 0,0005 for thickness, p = 0,0009 for patient's age and p = 0,02 for histological type. In analysis with two variables, including level, thickness was the variable that added most to the information on prognosis supplied by level. For the population of patients with melanoma levels III and IV significant differences in survival rate were associated with thickness (less than 2 mm or greater than or equal to 2 mm; p less than 0,001), though not with level. When the variables were studied separately, thickness and patient's age were significant (p = 0,02 and p = 0,03 respectively). Analysis with two variables, including thickness, showed that age was the variable that added most to the information on prognosis supplied by thickness.

Adolescent↗
PubMed1978

Lateral differences in habituation of ipsilateral head-turning to repeated tactile stimulation in the human newborn.

Lateral differences in habituation of ipsilateral head-turning to repeated tactile perioral stimulation following midline head restriction was studied in 44 full-term neonates. Left-sided stimulation had a significantly greater and faster decremental effect than right-sided stimulation. Even in the absence of tactile stimulation (Control Group), head-turning to the left decreased systematically whereas head-turning to the right did not. The transient efficacy of prior midline head restriction for the elimination of lateral differences in both spontaneous head movements and responsiveness to tactile input suggests that behavioral asymmetry is already well-established in the newborn.

Female↗
PubMed1977

Intra- and inter-modal effects of prior stimulation on cardiac responsiveness to repeated stimulation in the human newborn.

The effect of prior equivalent auditory and somesthetic input on cardiac acceleration responses to repeated auditory and somesthetic stimulation was studied in 56 healthy 2- or 3-day-old infants. Responsiveness to initial presentation of the reiterative auditory stimulus was significantly greater than to the reiterative somesthetic stimulus regardless of the modality stimulated during the preceding series. In contrast the course of response decrement to subsequent repeated presentations of both stimuli was significantly more rapid when the reiterative and prior stimuli were in different modalities (inter-modal) than when they were in the same modality (intra-modal). The findings demonstrate a modality difference in effect of anticedent input on initial responiveness and a greater efficacy of inter- than of intra-modal auditory and somesthetic stimulation for the habituation of neonatal cardiac responses to repeated stimulation.

Acoustic Stimulation↗
PubMed1976

Modality differences in the habituation and dishabituation of cardiac responsiveness in the human newborn.

The relative efficacy of (1) repeated auditory and somesthetic stimulation for the habituation of cardiac acceleration responses and (2) intramodal and cross-modal stimulation for the dishabituation of cardiac responses was studied in 45 full-term 2-day-old infants. Although the stimuli were equally effective initially, repeated presentation of the somesthetic stimulus had a greater decremental effect than repeated presentation of the auditory stimulus. The stimuli were equally effective in producing dishabituation when in a different modality from that of the habituating stimulus (cross-modal) but not when in the same modality (intramodal). Changes in the locus of stimulation without a change in modality were ineffective for producing dishabituation. The findings indicate the human newborn discriminates auditory and somesthetic inputs effectively and equally but does not discriminate contralateral from ipsilateral stimulation in either modality.

Acoustic Stimulation↗
PubMedDate not supplied

Blood cadmium levels in a general male population with special reference to smoking.

Blood-cadmium (Cd-B) level, blood pressure, and several biological parameters in blood were measured in 440 men who were not occupationally exposed to cadmium and who had a detailed smoking history. No significant correlation was found between Cd-B and blood pressure. Among biological parameters, those known to be related to smoking appeared significantly correlated with Cd-B. Analysis of smoking history showed that Cd-B is strongly elevated in current smokers, with a dose-effect relationship between daily consumption of tobacco and Cd-B; moreover, exsmokers had significantly higher Cd-B than nonsmokers. This finding shows that Cd-B partly reflects past exposure to cadmium.

Adult↗
PubMedDate not supplied

Prenatal exposure to lead and cadmium and psychomotor development of the child at 6 years.

In 1977, a hair sample was taken from 26 newborn babies and their mothers and analysed for lead and cadmium. Six years later, each of these 26 children was given a psychometric test (McCarthy Scales of Children's Abilities). Statistical analysis shows a significant negative relationship between the degree of in utero exposure to cadmium and lead and the child's motor and perceptual abilities. Any effect on memory or verbal skills was not statistically significant. Allowing for the confounding variables does not consistently affect these results.

Cadmium↗