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Biomedical subjects

T Miyazaki

Publications and source records attributed to T Miyazaki.

At least 865 records · Page 48Linked to original sources

[The development of a convenient enzyme-immunoassay method to detect human serum ferritin].

We have developed an enzyme-immunoassay (EIA) method which is easily and conveniently handled to detect human serum ferritin instead of using the radioisotopes. Rabbit anti human liver ferritin antiserum was adsorbed to a 96 well microplate. Then, sera from patients were put into each well following the addition of peroxidase-labelled rabbit anti human liver ferritin antiserum. Therefore, this is composed of so-called "sandwich" method. One of the beneficial characteristics in this method is to be able to examine many samples at once and easily. Based on this principle, this is clinically useful for screening the abnormal level of serum ferritin from various patients.

Ferritins↗

Cell surface markers of acute non-lymphocytic leukemias: leukemia type and its expression of C3 and Fc receptors.

Seventeen untreated human acute non-lymphocytic leukemias (ANLL) were classified into four groups according to the presence or the absence of complement receptor and Fc receptor for IgG and IgM: Group I having neither C3 nor Fc receptors, Group II having either C3 or Fc receptor and Group III having both C3 and Fc receptors. ANLL of Group II was further subdivided into two groups: Group IIa having only Fc receptor and Group IIb having only C3 receptor. The morphologic and cytochemical analysis of ANLL in these groups revealed that the most immature type with regard to their myeloid-monocyte lineage was Group IIb followed by Groups I, IIa and III. Two cases of Group IIb were regarded as M1 type by French-American-British (FAB) group classification and one of them had a Ph1-chromosome. The survival rate of patients in each group was investigated and Group IIb patients showed the tendency for the longest period of survival.

Acute Disease↗

[Extracranial metastases of brain tumors--a case report and survey of patients with extracranial metastasis sampled from a report on pathological autopsy cases in Japan].

A 36-year-old man who suffered from recurrence of hemangiopericytoma originating in the cerebellar tentorium and multiple extracranial metastasis over 14 years was reported. Analysis of the 104 cases of extracranial metastasis sampled from the Annual of the Pathological Autopsy Cases in Japan revealed that the frequency of extracranial metastasis is 3.8% of all brain tumors. Extracranial metastasis was frequently found in medulloblastoma, glioblastoma multiforme, malignant meningioma and ependymoma. Organs of frequent metastasis were the lung, bone, liver, pleura, and kidney. Bone metastasis was especially frequent in the vertebra.

Adult↗