Search PubMed⌕ Search

Biomedical subjects

T Miyasaka

Publications and source records attributed to T Miyasaka.

At least 127 records · Page 7Linked to original sources

A facile and regiospecific preparation of 6-alkyluridines.

2',3'-O-Isopropylideneuridine, upon lithiation and subsequent alkylation, was transformed to 6-alkyl derivatives in a regiospecific manner. After acidic treatment of the acetonides, 6-alkyluridines (methyl, ethyl, propyl, isopropyl, butyl, secbutyl, and hexan-3-yl) were obtained. 5'-Deoxy-6-alkyluridines (methyl, ethyl, and isopropyl) were also prepared by the same route from 5'-deoxy-2',3'-O-isopropylideneuridine.

Indicators and Reagents↗