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Biomedical subjects

T Mishina

Publications and source records attributed to T Mishina.

At least 37 records · Page 2Linked to original sources
PubMed1995

[A benign clear cell tumor of the lung that grew gradually over five years].

A 38-year-old man was found to have an abnormal shadow in his chest X-ray film during a general medical examination. A nodule with a homogeneous density and a clear margin was seen in the upper lobe of the right lung. Since this shadow gradually enlarged during a five-year follow-up period, he was admitted to our hospital. Chest contrast and dynamic CT scans and aortography showed characteristics of a benign tumor with somewhat rich vascularity. The doubling time of this tumor was about 430 days. Transbronchial brushing for cytologic study and a transbronchial biopsy showed no malignancy. However, the tumor was surgically resected because of its gradual growth over the five years. The resected tumor was histologically diagnosed as a benign clear cell tumor of the lung. This disease was first described by Leibow and Castleman in 1963, as a benign pulmonary tumor similar to metastatic renal cell carcinoma. This disease is extremely rare and only 61 cases have been reported: twenty cases, including the present case, in Japan and 41 in other countries.

Adenocarcinoma, Clear Cell↗
PubMed1994

[Evaluation of clinical efficacy and safety of cefpodoxime proxetil (CPDX-PR) in acute uncomplicated cystitis].

One hundred and fifty female patients with acute uncomplicated cystitis were given 200 mg of CPDX-PR twice daily for 3-7 days to evaluate both its overall clinical efficacy and its adverse effects. In 82 cases (Group I) in which it was administered for 3 days, the overall clinical efficacy, evaluated by the criteria proposed by the Japanese UTI committee, was excellent in 64 cases, moderate in 17 and poor in one, with the effective rate being 98.8%. In 35 cases (Group II) in which it was administered for 4-7 days, the overall clinical efficacy was excellent in 18 cases, moderate in 15 and poor in 2, with the effective rate being 94.3%. The overall clinical evaluation was not performed in another 33 cases because they were given CPDX-PR for more than 8 days or 300 mg/day. Subjective adverse effects such as hoarseness and lingual inflammation were observed in only one of the 150 cases, but they disappeared spontaneously after the cessation of administration of CPDX-PR. These findings suggest that CPDX-PR is one of the most effective and safe antibiotic in the treatment of acute uncomplicated cystitis.

Acute Disease↗
PubMed1993

[Prostatic weight estimation by the regression equation using transrectal ultrasonotomography].

The prostatic weight was evaluated in 264 patients with benign prostatic hyperplasia before transurethral resection of the prostate (TUR-P) by transrectal ultrasonotomography. In the first group of 121 among 132 patients, the weight of both the total prostate (EPWt) and the internal prostatic gland (EPWi) was estimated and compared to the actual weight of resected specimens (RPW). In the remaining 11 patients, EPWt was obtained but not EPWi because their prostatic gland echograms were obscure. The correlations between RPW and EPWi, and between RPW and EPWt in 121 patients were proved to be RPW = 0.999 EPWi-0.586 (r = 0.851), RPW = 0.537 EPWt-1.914 (r = 0.766), respectively. In the second group of 132 patients, the weight of the prostatic adenoma to be resected was estimated preoperatively by the measurement of EPWt and the application of the latter formula (CRPW). The correlation between RPW and CRPW was proved to be RPW = 0.930 CRPW-1.570 (r = 0.824). It is presumed from this study that preoperative estimation of EPWi or EPWt may be useful not only for selection of the treatment modality for BPH, namely TUR-P or open surgery, but also for prediction of an operation time in TUR-P.

Humans↗
PubMed1993

[A case of ectopic vas deferens with a chief complaint of male sterility].

A case of ectopic vas deferens in a 40-year-old male was reported. He visited our clinic with a complaint of male sterility for the past 10 years. Urological examinations revealed azoospermia, right renal aplasia and the ectopic insertion of right vas deferens into the right lower ureter with a blind-ending ureterocele. Bilateral testicular histological studies showed normal spermatogenesis in right testis and no spermatogenesis in left one. A vasovasostomy was performed. Sperm were seen in the semen 3 weeks after the operation. Including this patient, 54 cases (74 ectopic vas deferens) have been reported in the literature to date. The characteristics of age, subjective complaints, accompanied anomalies, diagnosis, treatment and the embryology are discussed.

Adult↗
PubMed1992

Intravesical instillation of adriamycin for bladder tumors.

In the present series of trials, Adriamycin (ADM) intravesical instillation therapy was found to be effective against tumors of papillary morphology measuring less than 10 mm in diameter that were of low pathological stage and low histological grade. The rate of complete disappearance increased in proportion to the concentration of ADM and the duration of retention of the drug, although the efficacy rates were almost the same in each trial. On the other hand, side effects on the bladder were reduced when the instilled solution was lower in concentration and the retention time was short.

Administration, Intravesical↗
PubMed1992

[Clinical statistics on outpatients at Mishina urological office between July, 1984 and December, 1990].

The total number of outpatients was 6,298. There were 4,293 males and 2,005 females, the male to female ratio being 2.1:1. The major diseases seen in the outpatients were benign prostatic hypertrophy, bladder dysfunction, chronic prostatitis, prostatic stones, ureteral stones, chronic cystitis, urethral stricture, and essential renal bleeding. The 102 (5.1%) patients with urethral diverticulum among 2,005 female patients were discovered by high pressure urethrography. There were 373 cases of urogenital malignancies including 205 of bladder tumor, 85 of prostatic carcinoma and 29 of renal tumor, 11 of which were incidentally found. Twenty of the 205 bladder tumors were found among the 703 cases of microhematuria.

Adolescent↗
PubMed1991

[Clinical statistics on inpatients and operations at Mishina Urological Office between July, 1984 to December, 1990].

The total number of inpatients was 1,309. There were 1020 males and 289 females, the male to female ratio being 3.5: 1. The major diseases seen in inpatients were benign prostatic hypertrophy, bladder tumor, prostatic carcinoma, ureteral stone, urethral diverticulum, bladder neck contracture, inguinal hernia and renal tumor. The total number of patients operated on was 1,211; 953 males and 258 females. These operations were performed at 11 hospitals using a semi-open system. Major operations were transurethral resections of prostatic and bladder tumor, subcapsular prostatectomy, castration, urethral diverticulectomy, nephrectomy, inguinal hernioplasty, ureterolithotomy, radical cystectomy and transurethral ureterolithotripsy. New operation methods were radical prostatectomy by Walsh's method, Kock pouch, penis prosthesis implantation, transurethral incision of bladder diverticular orifice, Gil-Vernet method for VUR and Stamey's method for stress incontinence. Major small operations and examinations for outpatients were transperineal prostatic needle biopsies, transurethral urethral and bladder mucosal biopsies, phimotomy, transurethral intravesical surgery and percutaneous renal cyst puncture.

Adolescent↗