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Biomedical subjects

T Minatogawa

Publications and source records attributed to T Minatogawa.

27 records · Page 2Linked to original sources

Results of tympanoplasty for congenital aural atresia and stenosis, with special reference to fascia and homograft as the graft material of the tympanic membrane.

The surgical management of congenital aural atresia is a challenging, complex procedure, and the risks are great. The otologic surgeon is responsible for keeping a patent external auditory canal and for achieving satisfactory hearing. The present report studied hearing changes that occurred after tympanoplasty and the long-term results of tympanoplasty in 12 cases of congenital aural atresia or stenosis. Patients were followed for more than 2 years after surgery. In four ears, an allograft of the tympanic membrane with an attached malleus was used, with a good graft take and hearing results. An autograft of temporal fascia was used in eight ears. Hearing acuity decreased in six of the eight ears and was maintained in two ears. Three primary surgery patients required revision surgery for postoperative restenosis of the external auditory canal. Some comments have been made with regard to this problem. Emphasis is also placed on the selection of patients for surgery using a thorough audiologic and roentgenologic evaluation.

Adolescent↗

Vulnerable site of the facial nerve. From histopathology of seven temporal bones.

In the present work, a series of studies was made of seven temporal bones taken from 5 newborns within 6 h of death. In the 5 cases considered in this study, all of which had suffered from severe circulatory disease of congenital or unknown origin, destruction of the facial nerve as well as severe congestions were noted. The following findings were common to all seven temporal bones. (1) Bleeding together with destruction of the nerve had originated in the mid-section of the tympanic portion and increased distally up to the distal portion of the mastoid. (2) Bleeding was restricted mainly to the inner side of the perineurium or in the nerve trunk. (3) There was little bleeding in the epineurium, with the exception of both temporal bones in one of the cases. Although destruction of nerve fibres and the perineurium was prominent in all cases, in six of the temporal bones, traces of nerve trunk remained as a mould, with or without erythrocytes. In one temporal bone in case 5, which survived only 16 days, most of the nerve fibres had changed into fibrous tissue around which bleeding and small vessels containing erythrocytes were prominent. From these findings, it is postulated that the pathological change in the Fallopian canal of six of the temporal bones resulted from acute congestion after birth (due to acute reduction of oxygen density in the arterial blood resulting from severe congenital heart disease), while that of the remaining temporal bone resulted from chronic congestion which had already existed during gestation. It may be concluded that disturbance of blood flow is likely to occur from and distal to the tympanic portion of the Fallopian canal and that this may be due to the peculiar structure of the blood vessels in this area.

Bone Diseases↗

The use of allograft stapes.

Since 1981, we have used the stapes allograft, singly or in combination with homograft incus, in 20 cases of tympanoplasty and in 7 cases of fixed stapes. All of the allograft stapes discussed were procured, processed and stored in 1980 by the Hyogo Ear Bank, the first to be established in Japan. The stapes allograft was used in three situations: an intact posterior canal wall, an open mastoidectomy cavity, or a fixed stapes (postinflammatory, congenital or otosclerotic). Two modalities of positioning of the donor stapes were attempted: (1) the allograft stapes was placed in the normal position and a shaped incus or cortical bone or tragal cartilage was placed on the top of the stapedial head and connected and (2) the allograft stapes was placed in the upside-down position and the columella was placed on the stapes footplate. Better results were obtained with the allograft stapes placed in the normal position. A two-stage operation, first to place an allograft stapes in the normal position with myringoplasty and then ossiculoplasty, was preferable to one-stage middle ear surgery.

Audiometry, Pure-Tone↗

The blood supply of the facial nerve in the human temporal bone.

The gross blood supply and intrinsic vascular anatomy of the facial nerve in the temporal bone are described, and their significance is discussed. At the vertical part of the facial nerve, the stylomastoid artery lies on its anteromedial side as far as the upper third of the nerve. The artery then loops around the lateral or medial side of the nerve, and divides into several branches. At the convex aspect of the genu, these branches anastomose with one another to form an arterial network, passing to the horizontal part. The petrosal branch of the middle meningeal artery reaches the geniculate ganglion and forms a profuse, fine arterial network. The main arterial trunk extends toward the second bend in the nerve, but it never reaches the vertical part. Studies on the draining veins are also described. Duplication of blood vessels from different sources was seen at the horizontal part of the nerve. This would suggest a special vulnerability of this area to vascular injury, since in our topographical study of Bell's palsy within two weeks of its onset, 72 out of 117 cases (61.5%) were found to have suprastapedial lesions.

Cadaver↗

Nasal septal hemangiopericytoma-like tumor: a case report with an immunohistochemical study.

Nasal hemangiopericytoma-like (HPCL) tumor is a rare vascular tumor and should be differentiated from typical hemangiopericytomas (HPCs). This study reports the case of an HPCL tumor in a 77-year-old man with histological and immunohistochemical features. After preoperative evaluation of the blood supply, the dark-red right intranasal tumor was resected completely via the right maxillary sinus. The final histopathological diagnosis was HPCL tumor based on several stains: vimentin (+), alpha-SMA (+), etc. Moreover, there were few p53 (+) cells and the Ki-67 and topoisomerase IIalpha labeling indices were both under 5%. These findings indicated that this tumor was a low-grade malignancy. The immunohistochemical investigations used are useful for making the diagnosis of HPCL tumor and determining the treatment, malignancy, and prognosis.

Aged↗