Studies on the persistent infection with measles virus in HeLa cells. I. Clonal analysis of cells of carrier cultures.
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Antigens↗
Biomedical subjects
T Minagawa
Publications and source records attributed to T Minagawa.
Studies on the persistent infection with measles virus in HeLa cells. II. The properties of carried virus.
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Animals↗
Studies on the persistent infection with measles virus in HeLa cells. 3. Immunolysis of cells in carrier state by anti-measles sera.
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Aluminum Silicates↗
Genetic control of the DNA maturation in the process of phage morphogenesis.
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Centrifugation, Zonal↗
Prevention of phage multiplication by quinomycin A.
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Anti-Bacterial Agents↗
[Training on eye glass expert as paramedical profession].
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Eyeglasses↗
Shut-off of early messenger RNA synthesis in E. coli infected with phage T2.
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Binding Sites↗
[Chairman's comment on the symposium on retinal detachment].
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Humans↗
Endogenous gamma interferon produced in central nervous system by systemic infection with Theiler's virus in mice.
Theiler's virus GD VII strain causes acute encephalomyelitis by intracerebral inoculation. We established acute encephalomyelitis in mice by the intravenous (i.v.) inoculation of Theiler's virus GD VII strain. Replication of Theiler's virus injected i.v. could be observed in both the brain and spinal cord of mice, and interferon (IFN)-gamma could be detected in the extracts of brain and spinal cord in parallel with viral replication. Furthermore, by the injection of anti-IFN-gamma monoclonal antibody (mAb) on Day 1 post-infection (p.i.), mortality and virus titres in the spinal cord increased compared with the control mice treated with normal rat globulin. The histological exacerbation of inflammation was observed in spinal cord of anti-IFN-gamma mAb-treated mice. These results indicate that endogenous IFN-gamma, produced locally in the brain and spinal cord of mice through both antiviral action and anti-inflammatory action of IFN-gamma in central nervous system, plays an important role in Theiler's virus infection.
Animals↗