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Biomedical subjects

T Mimaki

Publications and source records attributed to T Mimaki.

75 records · Page 5Linked to original sources

Dandy-Walker cyst associated with occipital meningocele.

Dandy-Walker cyst associated with occipital meningocele is very rare. Only 12 patients have been reported. We report a female infant with Dandy-Walker cyst and occipital meningocele whose diagnosis was suspected antenatally by in utero ultrasonography. At birth, head circumference was normal for 37 weeks gestation. She underwent surgical repair of the occipital meningocele immediately after birth. The post-operative course was uneventful until the sixth day of life when progressive enlargement of the head with progressive ventricular dilatation was recognized. Communication between the posterior fossa cyst and the occipital meningocele was confirmed neuroradiologically; the occipital meningocele may have compensated for the increased intracranial pressure in fetal life.

Dandy-Walker Syndrome↗

Bilateral occlusions in the cervical portion of the internal carotid arteries in a child.

An 8-year-old boy with a history of recurrent tonsillitis and cervical lymphadenopathy developed acute hemiplegia. Cerebral angiography revealed bilateral occlusions of the cervical portion of the internal carotid arteries. Cerebral arterial occlusion in childhood has been attributed to many causes, e.g., trauma and infections of the neck. In the present case, though not clearly proved, inflammatory processes may have been related to the occlusion.

Arterial Occlusive Diseases↗

Regional cerebral blood flow, clinical manifestations, and age in children with moyamoya disease.

In children with Moyamoya disease, transient ischemic attacks often occur during hyperventilation, and the frequency of attacks usually decreases with advancing age. To elucidate the mechanism of the attacks, the regional cerebral blood flow was measured during rest and/or hyperventilation in children aged 3-16 with Moyamoya disease. Regional cerebral blood flow during rest was significantly higher in younger children with Moyamoya disease, and it progressively decreased with advancing age through childhood. During hyperventilation, regional cerebral blood flow decreased in all the children, although blood flow in younger children was still higher than that in the older children. Nevertheless, transient ischemic attacks were more readily precipitated by hyperventilation in the younger than in the older children. Cerebral metabolic demand is much higher in the first decade of life than in later decades. Therefore, it seems likely that even a moderate reduction in cerebral blood flow can cause metabolic impairment in young children. Such high cerebral metabolic demand may play an important role in the frequent occurrence of transient ischemic attacks in young children with Moyamoya disease.

Aging↗