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Biomedical subjects

T Mendel

Publications and source records attributed to T Mendel.

32 records · Page 2Linked to original sources

[Headache concurrent with the onset of ischemic stroke].

The aim of the study was to assess the occurrence of headache in acute ischaemic stroke and its association with type, aetiology and localization of stroke. 342 patients with stroke were analysed. Their average age was 70.8 +/- 13.1. Headache was observed in 17.8% stroke patients. There was no correlation between headache and size of ischaemic lesion in CT. Headache was observed in 43.1% of patients with small foci localized in deep structure, and in 33.3% of large cortical-subcortical foci. The analysis between the frequency of headache and type of stroke according OCSP classification revealed that headache occurred statistically significant more frequent in POCI.

Acute Disease↗

[Brain stem syndrome after cervical chiropractic manipulations].

This is a case report of a 41-year old man who had ischaemic lesion in the pons following chiropractic manipulation. He had brainstem syndrome with right hemiparesis. He improved. After 4 a year follow-up he is in a very good condition.

Chiropractic↗

[Demonstration of cardiac arrhythmias in multi-infarct dementia and ischemic stroke using Holter monitoring].

The occurrence of the cardiac arrhythmias was estimated by using 24-hour ECG Holter monitoring in 30 patients with multi-infarct dementia and in 30 with ischaemic stroke. Holter monitoring revealed pathological cardiac arrhythmias in 36.7% patients with multi-infarct dementia and in 40% with single ischaemic focus in the brain. It also allowed to reveal more frequent occurrence of cardiac arrhythmias in patients with ischaemic stroke (40%), than standard ECG (17%).

Adult↗

[Ischemic stroke in patients under 50 years of age with special reference to its etiology and risk factors].

Eighty-four patients with ischaemic stroke aged 18-50 years were analysed. They had been treated in the years 1985-1989. Forty-five of them were followed up. In a high proportion of cases stroke was a result of thrombosis. Many risk factors were found in this group, mainly hypertension. In most cases stroke was serious, in several cases post-stroke epilepsy and poly-infarction dementia developed.

Adolescent↗

[Hemodilution in the treatment of cerebrovascular disorders].

Haemodilution includes intravenous administration of plasma-replacing solutions and/or blood letting for changing the rheological properties of blood, and for improvement of microcirculation. Three methods of haemodilution various plasma substitutes are given: dextran, hydroxyethyl starch (HES), electrolyte solutions (e.g. Ringer's solution, normal saline, 5% glucose, colloidal plasma, protein solutions), plasma, albumins. The controversial results of clinical trials of the method for therapeutic purposes are discussed. In the light of the reports as yet, it seems that the best results are obtained using normovolaemic haemodilution with administration of HES.

Blood Volume↗

[Prevalence of certain risk factors in lacunar strokes as compared with cortico-subcortical strokes].

Clinical records were reviewed to analyse occurrence of hypertension and other risk factors that may predispose to the development of lacunar stroke. The comparison of risk factors associated with deep, small, ischaemic lesions of the brain (revealed in 67% by CT, in 31% by MRI and in 2% by autopsy) and large superficial or superficial and deep ischaemic lesions (diagnosed in 89% by CT, 4% by MRI and 7% by autopsy) was done. Hypertension, treated and untreated, was more frequent in lacunar stroke, but the difference was not statistically significant. Statistically significant difference was found in large stenotic lesions of internal carotid artery, which were more common in patients with large superficial or superficial and deep lesions (watershed area) and in moderate stenotic lesions of internal carotid artery, which were more common in patients with lacunar stroke. The results suggests that lacunar stroke may be caused by cerebral embolism from carotid sources.

Adult↗

[The importance of transoesophageal echocardiography in establishing of the source of cerebral embolism].

Transesophageal echocardiography becomes widely used in patients suspected of cerebral embolism. This examination is characterized by higher than transthoracic echocardiography sensitivity for detection of left atrial thrombus. Patent foramen ovale and atrial septal aneurysm have been recognized more often in patients with embolic stroke than in control group. Another potential source of embolism is aortic atheroma especially when protruding or ulcerated. Transesophageal echocardiography allows for identification of embolic source in more than 50% of examined patients.

Cardiovascular Diseases↗

[Risk factors in patients with stroke].

The prevalence of risk factors in relation to age was analysed in 470 patients with ischaemic or haemorrhagic stroke. In all patients the most frequent risk factor was hypertension: 54-72% in haemorrhagic stroke, and 44-49% in ischaemic stroke. Moreover, in both types of stroke in the group aged up to 50 years the proportion of heavy smokers was high: 54% in haemorrhagic and 44% in ischaemic stroke. In the group aged 51 to 65 years coronary disease was present in 44% of haemorrhagic and 41% in ischaemic stroke. In patients aged 65 years coronary disease was present in 59% of haemorrhagic strokes and in 33% of ischaemic strokes. Arrhythmia was noted in 45% of haemorrhagic and 36% of ischaemic strokes. The presence of risk factors had an influence not only on the incidence of strokes but also on their course and prognosis, this was true especially of ischaemic stroke, since in dying patients, especially those aged below 50 years, the prevalence of hypertension, smoking and coronary disease was higher. In patients aged over 65 years mortality was higher in those with arrhythmias and coronary disease.

Adult↗

[Polyneuropathy in the course of Hodgkin's disease: case report].

Polyneuropathy in neoplastic process practically may occur in every stage, before clinical signs, together with clinical signs and in the last period. In some percent of patients polyneuropathy may outstrip manifestation of neoplastic process even for many years. We present a 61-year-old patient in whom signs of polyneuropathy appeared before the signs of essential disease - Hodgkin's disease. Our case confirms the necessity of very careful and precise diagnostics of polyneuropathy with unclear aetiology.

Demyelinating Diseases↗

[Persistent foramen ovale and cerebral embolism].

Paradoxical embolism through persistent foramen ovale is one of the mechanisms of cardiogenic cerebral embolism. Transesophageal and transthoracic echocardiography and transcranial Doppler ultrasound (TCD) allow to assess the connection between ischaemic stroke, and to indicate specific treatment.

Adult↗

[Lacunar strokes: clinical conditions vs. localization of lesions in neuroimaging studies].

Clinical records of 89 patients with lacunar stroke were reviewed, to evaluate the occurrence of neurological syndrome and to correlate the frequency of its signs with the localization of ischaemic lesions seen in neuroimaging examinations. "Pure" motor paresis (50%) and sensory-motor paresis (27%) were the most common clinical syndromes. The localization in putamen and corona radiata (37%), or in anterior part of the internal capsule and in the head of the caudate nucleus (35%) were the most frequent sites of localization. In the group of patients with lesions in anterior part of internal capsule or with lesions in putamen and corona radiata "pure" motor paresis was the most common clinical syndrome. Additionally, in the group of patients with lesions in putamen and corona radiata sensory motor paresis was also frequently observed (44%). During one year of follow-up 22 patients died. Dysarthria and disability (Barthel Index < 60) were the independent predictors of one year mortality. Non-neurological complications were the main cause of death.

Aged↗

[Annual survival rates in lacunar stroke in relation to neurological status, risk factors and applied anti-aggregation treatment].

Lacunar stroke accounts for 20-25% of all ischaemic strokes. It is believed that the prognosis in this stroke is relatively good, with annual mortality being 9.8% to 11.3%. In the analysis of the Warsaw Stroke Register this mortality was much higher--about 25%. The purpose of the present study was to assess the factors increasing the probability of death in lacunar stroke based on a one-year follow-up of 113 patients (67 males and 48 females), mean age 67.3 +/- 11.2 treated at the II Department of Neurology, Institute of Psychiatry and Neurology. The total one-year mortality was 23%. In the group of patients dying in that year hypertension was found in 88% and diabetes in 27%, while in the surviving group these diseases were found in 72% and 18% respectively. The differences between groups were not significant. Considering the effect of other risk factors (age, fitness status assessed with modified Barthel index) it was demonstrated that the risk of death increased with increasing age (relative risk 1.03, 95% CI 1.001-1.05) and with the degree of dependence on the help of others, Barthel index < 60 (RR = 1.49.95%, CI 1.24-1.66). In the analysis of the effect of antiaggregation treatment the mortality was lower in aspirin-treated patients (300 mg daily) with cumulated annual survival rate 79.8 as compared to the not treated patients in whom it was 58.2. The difference was not significant, probably due to small number of cases.

Age Distribution↗