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Biomedical subjects

T McGill

Publications and source records attributed to T McGill.

31 records · Page 2Linked to original sources
PubMed1980

Orbital cellulitis of dental origin: differential diagnosis and the use of computed tomography as a diagnostic aid.

This report illustrates the spread of odontogenic infection to the orbit and the usefulness of the CT scan for the differential diagnosis of periorbital vs orbital cellulitis and abscess. It shows the necessity for close follow-up of patients with odontogenic infection so that life-endangering complications may be treated promptly. Finally, this patient illustrates the fact that, in some cases, a dental infection may be so virulent that drainage through the tooth and antibiotics do not provide control. Tooth removal and prompt incision and drainage are required for adequate treatment.

Adolescent↗
PubMed1980

Treatment of subglottic hemangioma with the carbon dioxide laser.

Congenital subglottic hemangioma is a potentially life-threatening lesion usually presenting in the first three months of life. Over the years, multiple treatment modalities have been advocated. However, none has been uniformly successful, and morbidity and mortality remain high. With the advent of the carbon dioxide surgical laser, it soon became apparent that this was an ideal tool for the pediatric larynx. The already documented properties of the laser have led to the application of this form of tissue destruction in 11 patients with subglotic hemangioma. This modality has proven to be a safe, effective and rapid means of treating this troublesome lesion.

Female↗
PubMed1979

The use of the carbon dioxide laser in the pediatric airway.

Congenital and acquired lesions of the pediatric airway present difficulties in management. Until recently, correction of these problems frequently involved an external approach to the larynx and trachea. Development of fiberoptic instrumentation, as well as the introduction of the Zeiss operating microscope, has now given the surgeon a new means to visualize the larynx and trachea. Soon after its development, the carbon dioxide surgical laser was coupled to these instruments to permit an extremely precise form of tissue excision and ablation. Its unique properties, including an extraordinary hemostatic effect, as well as minimal postoperative edema and scarring, make it an ideal tool for management of lesions of the pediatric airway. It has been employed successfully in the treatment of 177 lesions.

Bronchial Neoplasms↗
PubMed1978

Surgical advances in the treatment of lesions of the pediatric airway: the role of the carbon dioxide laser.

Transoral microsurgery of the larynx has now made it possible to treat multiple lesions heretofore only treatable by external approach. The introduction of the surgical carbon dioxide laser has been the single greatest advance in transoral surgery of the airway in the past 15 years. This modality of therapy offers many features not found in any other known form of surgery. It is especially useful in the pediatric airway where the avoidance of edema and the need for minimal scarring is most critical. Its unique aspects make this form of treatment most desirable in the pediatric laryngotracheal region.

Carbon Dioxide↗
PubMed1975

Exposure to asbestos and laryngeal carcinoma.

One hundred and nineteen male patients with squamous carcinoma of the larynx and 119 matched controls with various non-malignant diseases were questioned about their exposure to asbestos. Thirty-three patients and three controls had experienced an important degree of exposure to asbestos. The difference between the two groups was statistically highly significant.

Adult↗
PubMedDate not supplied

Fibrous dysplasia.

The controversy is this case centers around the management of this lesion, not the differential diagnosis. All the consultants agreed that the history, physical, and CT findings were consistent with various fibroosseous lesions, the most likely being fibrous dysplasia. The need for additional tests varied with a bone scan (Dr. Kearns), a bone scan and CT scan (Dr. McGill), and MRI, MRI angiogram, bone survey, BUN, creatinine, calcium, and phosphorus (Dr. Potsic). Cosmetic and functional changes were considered priorities for the consultants, with orbital compression, malocclusion, tooth eruption, nasal obstruction, and sinusitis (Dr. Kearns), nasolacrimal duct obstruction and orbital compression (Drs. McGill and Potsic) being the concerns. Because this lesion is benign and slow-growing, the consensus is that surgery should be reserved for functional or cosmetic compromise. But how aggressive should one be and what approach should be used? The approaches varied with midface degloving or lateral rhinotomy (Dr. Kearns), midface degloving (Dr. McGill), or a Caldwell-luc and lateral rhinotomy (Dr. Potsic). Assessment of this tumor postoperatively should be with patient examinations and serial CT scans. None of the consultants worried about sarcomatous changes in this tumor.

Facial Bones↗
PubMedDate not supplied

Carcinomatous encephalomyelitis with auditory and vestibular manifestations.

A clinical and pathological study of carcinomatous encephalomyelitis is presented. Attention is drawn to the various types of nonmetastatic paraneoplastic syndromes and their particular association with oat cell carcinoma of the lung. The feature of special interest in this study is the onset with otologic symptoms, sudden deafness in the left ear and vertigo, at a time when the neoplastic basis for the disease was not clinically evident. The most striking change in the left temporal bone is the almost total loss of cochlear neurons in Rosenthal's canal and degeneration of both divisions of the vestibular nerve. The organ of Corti and stria vascularis are normal throughout the cochlear duct. The vestibular sense organs are normal. The left cochlear nucleus is devoid of neurons, this neuronal loss is accompanied by a well developed astrocytic and microglial response similar to that in the medulla and spinal cord. This represents a carcinomatous sensory neuropathy involving the left VIII nerve with simultaneous involvement of the left cochlear nucleus. The pathogenesis of this condition still defies explanation, but there are some insights in the autoimmune sector.

Carcinoma, Small Cell↗
PubMedDate not supplied

Histopathological observations on the cochlear changes in otosclerosis.

Alterations in the dimensions of the basilar membrane and spiral ligament have been implicated in the pathogenesis of sensorineural hearing loss in otosclerosis. The histopathological findings in nineteen temporal bones with otosclerotic involvement of the cochlear endosteum are reviewed. Hyalinization and decrease in the width of the spiral ligament are the only consistent findings related to the otosclerotic focus in these temporal bones. The width of the basilar membrane is normal. The hair cell population and the stria vascularis are normal for the age group.

Atrophy↗
PubMedDate not supplied

Management of choanal atresia with the carbon dioxide laser.

Congenital choanal atresia frequently demands immediate recognition in the newborn, and provision of a nasal airway as soon as possible. A variety of techniques are available to correct this problem, but none is entirely satisfactory. Transpalatal procedures are associated with significant morbidity in the newborn, and transnasal microsurgical procedures are less predictable when a thick bony plate is present in the choanal obstruction. Transnasal resection with the CO2 laser has been carried out in seven patients (ten sides), whose ages ranged from 16 hours to 14 years. From this early experience, it appears that the procedure is entirely feasible and convenient. It seems to have significant advantages over conventional microsurgical techniques. Eight out of ten choanae have remained patent for four months or more. A lumen keeper is needed during the immediate postoperative period for at least two to three weeks. The procedure is associated with minimal morbidity.

Adolescent↗
PubMedDate not supplied

Benign tumors and lesions of the larynx in children. Surgical excision by CO2 laser.

Benign lesions of the airway in infants and children may endanger the airway and compromise laryngeal function. The CO2 laser provides an elegant method of transoral surgical excision without compromising laryngeal function or airway competence. It avoids the risks of such other treatment modalities as external surgical approaches, prolonged steroid therapy, and radiation. It is applicable to a wide variety of lesions without the necessity of tracheotomy. Hospitalization is minimized. Ten cases are presented to show the wide applicability of this technique. Gross pathology and pre- and postoperative findings are demonstrated and discussed, as is the safety and efficacy of the laser soft-tissue interaction.

Carbon Dioxide↗
PubMedDate not supplied

Carbon dioxide laser in subglottic hemangioma. An update.

Congenital subglottic hemangioma is a potentially life-threatening lesion which frequently presents before the age of 6 months. Many forms of therapy have been advocated for the treatment of this difficult lesion. The use of the carbon dioxide laser has been advocated in the past and this report represents an update in treating 31 patients from 1975 to 1983. The success rate was 94% and the complication rate was 6.5%. This form of therapy is an effective and valuable addition to those already available for this troublesome lesion.

Carbon Dioxide↗