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Biomedical subjects

T McCarthy

Publications and source records attributed to T McCarthy.

At least 73 records · Page 4Linked to original sources
PubMed1984

Intrauterine devices and pelvic inflammatory disease.

There is convincing clinical evidence that PID is more common in IUD users than in users of other contraceptive methods. There appears to be a smaller but significant increase when IUDs are compared with sexually active noncontraceptive users. However, the incidence of PID severe enough to warrant hospitalization is only of the order of 1 to 2 per 1,000 women per year. The question which remains is whether beyond this low figure of moderate and severe disease there is a much higher incidence of subclinical PID which may result in complications for IUD users. Development of a marker such as C-Reactive protein or the split complement component C3d to detect mild PID would prove invaluable in the elucidation of several crucial problems in the clinical management of women using IUDs.

Actinomycosis↗
PubMed1983

A randomised comparative evaluation of the copper 7, multiload copper 250 and T copper-22OC IUDs.

Two new Cu-IUDs, the TCu-22OC and Multiload Cu250, were evaluated against the Cu7 in 1,199 subjects in a randomised, multicentric trial using a common study protocol. During the 2 years following insertion, cumulative first-segment rates for total use-related terminations showed no significant differences between the 3 devices; however, the Cu7 had a significantly higher termination rate for accidental pregnancy compared to the TCu-22OC and its expulsion rate was significantly higher than the ML Cu250. The rate of accidental pregnancy was higher and the expulsion rate lower with the ML Cu250 compared to the TCu-22OC but these differences were not significant. The results are discussed in relation to IUD design and their application in family planning.

Adult↗
PubMed1980

Uterine rupture as a complication of second trimester abortion using intraamniotic prostaglandin E2 and augmentation with other oxytocic agents.

Two cases of ruptured uterus are presented following attempted induction of midtrimester abortion using intraamniotic prostaglandin E2 and augmentation with other oxytocic agents. With continued uterine stimulation the diagnosis of rupture may not be obvious and the diagnostic features are discussed. Patients of high parity appear to be particularly susceptible to uterine rupture during induced midtrimester abortion.

Abortifacient Agents↗
PubMed1980

Clearance of technetium 99m-labeled sulfur colloid particles from the blood in normal dogs and in dogs with hepatic granulomata.

The clearance of technetium 99m-labeled sulfur colloid particles from the blood was studied in a series of seven clinically normal dogs. The effect of recent (6 hours) injections of bacteria bacillus Calmette-Guerin or Corynebacterium parvum markedly impeded the clearance of the colloid from the blood, due to a partial blockade effect. This phenomenon was reversible. When multiple experimentally induced hepatic granulomatous lesions were present, the clearance was similarly impeded. In contrast, however, this was not a reversible event. The possible application of this technique to diagnosis was discussed.

Animals↗
PubMed1979

The premature breech: trial of labor or cesarean section?

Sixty-six premature breech deliveries were studied retrospectively. Forty-eight patients were permitted a trial of labor, 47 of whom ultimately delivered vaginally. Eighteen patients underwent cesarean section as soon as possible after their arrival at the delivery suite. When Apgar scores, perinatal mortality rates, cord prolapse, and entrapment of the aftercoming head are considered, cesarean section is probably the safer course of management for the patient with a footling breech infant, especially when the infant weighs 1500 g or less. However, the data indicate that a trial of labor can be safely undertaken in the presence of a premature frank or complete breech presentation.

Anesthesia, Obstetrical↗
PubMed1977

Memorial oration.

Explore the source record for details and available documents.

Attitude to Health↗
PubMed1977

Regional intralymphatic infusion (ILI) of irradiated tumor cells with evidence of distant effects.

A case of canine lymphoma with radiographically-documented involvement of the para-aortic nodes is reported. Intralymphatic infusions (ILI) of cultured irradiated autochthonous tumor cells to remote lymph node bearing areas were associated with a dramatic initial shrinkage of the para-aortic lymphadenopathies. Three ILI timing schedules were used consecutively during a course of 10 treatments, allowing a comparison of responses in the same animal. The reported case suggests that a normal lymph node can be effectively "stimulated" by the same agent approximately every 3 weeks. A possible schedule for intralymphatic infusion is proposed for further investigation.

Animals↗
PubMedDate not supplied

West Nile virus surveillance in Connecticut in 2000: an intense epizootic without high risk for severe human disease.

In 1999, Connecticut was one of three states in which West Nile (WN) virus actively circulated prior to its recognition. In 2000, prospective surveillance was established, including monitoring bird deaths, testing dead crows, trapping and testing mosquitoes, testing horses and hospitalized humans with neurologic illness, and conducting a human seroprevalence survey. WN virus was first detected in a dead crow found on July 5 in Fairfield County. Ultimately, 1,095 dead crows, 14 mosquito pools, 7 horses, and one mildly symptomatic person were documented with WN virus infection. None of 86 hospitalized persons with neurologic illness (meningitis, encephalitis, Guillain-Barré-like syndrome) and no person in the seroprevalence survey were infected. Spraying in response to positive surveillance findings was minimal. An intense epizootic of WN virus can occur without having an outbreak of severe human disease in the absence of emergency adult mosquito management.

Animals↗
PubMedDate not supplied

An outbreak of multidrug-resistant Salmonella typhimurium food poisoning at a wedding reception.

An outbreak of gastrointestinal illness among 127 persons attending a wedding reception in Dublin was investigated. One hundred and fifteen wedding guests were interviewed and information obtained about demographic and clinical characteristics, and food consumed at the reception. Faecal samples from ill guests were submitted for microbiological examination and environmental investigations conducted at the catering facilities. Fifty-eight cases (diarrhoea within three days after having eaten at the reception) were identified. Forty-six cases submitted stool samples, of which 39 were culture positive for Salmonella typhimurium. Two isolates were phage-typed and found to be DT 104. Turkey was identified as a potential vehicle for this outbreak. A sample of litter from young birds at the poultry farm which had supplied the turkeys also tested positive for Salmonella Typhimurium DT104. In the Republic of Ireland S.typhimurium accounts for almost 50% of all human salmonella isolates. Epidemiological and microbiological studies which relate the human and animal spectrum of this disease need to be undertaken as a priority.

Adolescent↗