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Biomedical subjects

T Maehara

Publications and source records attributed to T Maehara.

At least 163 records · Page 9Linked to original sources
PubMed1988

Prediction of severe obstruction to right ventricular outflow after repair of tetralogy of Fallot and pulmonary atresia.

Cineangiograms were available for a quantitative retrospective study along with complete clinical information in 96 patients who underwent intracardiac repair of tetralogy of Fallot with pulmonary atresia. Multivariate analysis determined that the risk factors for too high a ratio (greater than or equal to 1) between the peak pressure in the right ventricle and that in the left, in the operating room about 30 minutes after repair, were as follows: size of the patient, small size of the right and left pulmonary arteries, and a larger number of large aortopulmonary collateral arteries. When, according to the multivariate equation, the predicted probability of this ratio being equal to or greater than 1 is 50% or more, consideration may be given to preliminary operations before repair; when the predicted probability is 70% or more, complete repair at that stage may be unwise.

Body Surface Area↗
PubMed1987

Intermediate-term fate of cryopreserved allograft and xenograft valved conduits.

Actuarial freedom from reoperation for obstruction in 147 patients receiving cryopreserved or fresh allograft valved conduits between a ventricle and the pulmonary arteries was 94% at 3.5 years. The 2 patients undergoing reoperation were 6 and 36 months of age at the time of insertion of the allograft. Among 24 patients in whom cardiac catheterization was performed on indication late postoperatively, 5 had gradients of more than 40 mm Hg across the conduit. For comparison, among 78 patients receiving xenograft or irradiated allograft valved conduits, the percentages of freedom from conduit reoperation at 3.5, 5, 10, and 15 years were 99%, 95%, 59%, and 11%, respectively. The diameters of the allograft and xenograft valves inserted varied directly with the age and size of the patients, but in patients 3 to 5 years of age, allografts with a diameter of at least 21 mm could usually be used.

Aorta↗
PubMed1987

Differences of sensitivity to autologous cytotoxic lymphocytes between primary tumor and its cervical lymph node metastases.

Antigenic differences between primary tumors and their cervical lymph node metastases of 12 patients with head and neck cancers were examined by measuring their sensitivity to cytotoxic lymphocytes (CL). Cytotoxicity was induced by autologous mixed lymphocyte (CL). Cytotoxicity was induced by autologous mixed lymphocyte tumor cell culture (MLTC), and further cultivation with recombinant interleukin-2 (rIL-2). The effector cells which were used in this study consisted of OKT3+8+ and OKT3+4+ subpopulations. Their cytotoxic nature was different from lymphokine activated killer cell (LAK cell) activity. Cytotoxicity of CLs stimulated by autologous primary tumor cells (CLP) was observed in 7 out of 12 patients (58.3%). In contrast, cytotoxicity of CLs stimulated by metastatic tumor cells (CLM) was observed in 4 out of 12 patients (33.3%). In the cases in which both CLP and CLM were successfully induced, cross-reactivity tests and cold target inhibition tests were performed. These results suggested that a reduction in immunogenicity had occurred at the metastatic site, and sensitivity against autologous CL was different between primary and metastatic tumor cells.

Adenocarcinoma↗
PubMed1987

Angiographic revascularization of the brain after encephaloduroarteriosynangiosis: a case report.

Preoperative and postoperative angiograms of a 13-year-old Japanese girl with moyamoya disease are compared. She underwent an indirect extracranial/intracranial bypass operation called encephaloduroarteriosynangiosis (EDAS). Post-EDAS angiograms clearly show revascularization of the brain through the donor scalp artery and decrease in moyamoya vessels, leptomeningeal anastomoses, and preexisting spontaneous transdural anastomoses.

Adolescent↗
PubMed1987

Congenital defect of posterior elements of the axis.

A congenital defect of the posterior elements (spinous process and vertebral arch) of the axis was observed in a 20-year-old man. This anomaly was detected by coincidence during roentgenographic study of the cervical spine for the investigation of headaches and neck pain following trauma. The clinical symptoms were relieved by conservative therapy, and the patient returned to a normal life.

Adult↗
PubMed1987

[Small-cell carcinoma of the lung relapsing at the primary site three years after radiation therapy with chemotherapy].

A 55-year-old man was diagnosed as having limited disease (T2N2M0, stage III) of small-cell carcinoma of the lung. He underwent radiation therapy (60 Gy in 30 fractions) in addition to combination chemotherapy, resulting in complete response with advantage for irradiation. Relapse in the primary site was seen three years after completion of the initial treatment. As a result, retreatment was started using radiation therapy (50 Gy in 25 fractions) with chemotherapy. The tumor almost disappeared again. Subsequently, cerebral metastasis was observed in the fourth year, indicating clinical and prognostic significance. Thoracic irradiation contributed to prolonged survival in this case. The most effective manner of combining irradiation and chemotherapy and the most efficacious doses were discussed.

Carcinoma, Small Cell↗
PubMed1986

Chondroblastoma of temporal bone.

The case of a 55-year-old female with chondroblastoma arising from the left temporal bone is presented. Although 10 cases of temporal chondroblastoma have been reported, this is the first in which plain radiography, pluridirectional tomography, computed tomography (CT) and angiography were performed. We discuss the clinical and radiological aspects of this rare tumor.

Cerebral Angiography↗
PubMed1985

Zoonotic subcutaneous filaria of undetermined classification.

A necrotic adult male filaria was found in sections of a dense, fibrous, subcutaneous nodule excised from below the breast of a 61-year-old woman, resident of Mie Prefecture in Honshu, Japan. Owing to its necrotic condition, and to a lack of essential knowledge of the comparative micro-anatomy of filarial worms, a differentiation between Dirofilaria and Dipetalonema species, or member of a related group, was not possible.

Animals↗