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Biomedical subjects

T Maeda

Publications and source records attributed to T Maeda.

At least 1,225 records · Page 68Linked to original sources
PubMed1985

[A study of bone metastasis of cervical carcinoma by bone scintigraphy].

In carrying out bone scintigraphy in 224 cases over the 5 years from June, 1978 to May, 1983 as a part of the post-treatment management of cervical carcinoma, we obtained the following findings concerning bone metastasis. Bone metastases were seen in 12.5% (28 cases) of the subjects, about 6% of the total post-treatment cases of cervical carcinoma in the corresponding period (466 cases). Bone metastases were seen in 9.3% (16/172) of post-operative cases, compared with 23.1% (12/52) of non-operative cases. Bone metastases were not seen in clinical stages Ia through IIa (49 cases) but were seen in IIb or higher stages. Bone metastasis rates by histological type, according to WHO classification, were 12.8% (26/203) in squamous cell carcinoma, 5.9% (1/17) in adenocarcinoma, and 25% (1/4) in adenosquamous carcinoma. Among the squamous cell carcinoma cases, small cell non-keratinizing type had the highest bone metastasis rate (p less than 0.05). Of 172 post-operative cases, 20.8% (11/53) of those with lymph node metastasis exhibited bone metastasis, higher than the 4.2% (5/119) in cases without lymph node metastasis. As to CPL classification, bone metastasis was seen more often in L type (18.8%) than C(0.0%) or P types (6.6%). Our risk classification of 168 cases demonstrated that bone metastasis was not seen in risk I group (74 cases), but was seen in 6.7% (1/17) of risk II group and in 19.0% (15/79) of risk III group. Twenty-eight cases with bone metastasis included 11 cases with local recurrence, 8 with pulmonary metastases, 4 with hepatic metastases and 4 with Virchow's lymph node metastases.(ABSTRACT TRUNCATED AT 250 WORDS)

Adenocarcinoma↗
PubMed1985

[CO2 laser in treating head and neck cancer].

CO2 laser is especially useful in treating cancer of tube- and cavity-organs. For carcinomas of the tongue, we have employed three types of laser usage. Carcinomas confined within the mucosa are treated by laser alone. For carcinomas invading the muscle to some extent, we make a mass reduction surgery by means of laser which is followed by (chemo)radiotherapy. Carcinomas with extensive muscular invasion are first treated with induction chemotherapy. If the chemotherapy is effective, we add laser surgery for the purpose of mass reduction and chemoradiotherapy follows. 26 patients were treated and none has developed local recurrence. For glottic carcinomas, we have applied laser in two ways: laser surgery alone and laser combined with (chemo)radiotherapy. We have treated 58 patients with glottic carcinoma. 14 developed local recurrence. Of these 14, 13 were successfully treated but the other died because he refused to have further treatment.

Antineoplastic Agents↗
PubMed1985

[Evaluation of myocardial perfusion by intravenous contrast echomyocardiography].

For the echocardiographic assessment of intramyocardial blood flow distribution by intravenous contrast echocardiographic technique, we measured the echo intensity of a point (phi 6 mm) in the interventricular septum using a lightmeter in end-diastole before and after the intravenous injection of various dosages of ether or hydrogen peroxide in one open-chest and four closed-chest dogs. Before the injection of contrast media, the echo intensity of the myocardium varied within a range of 6.1 +/- 4.6% After the injection of ether or hydrogen peroxide, the echo intensity of the myocardium increased. After the occlusion of the left anterior descending artery, echo enhancement of the left ventricular wall occurred, except for the left ventricular anterior wall and the interventricular septum. Between dosage (x) and % increase (y), relations of y = 127x - 3, in ether and y = 1.17x + 1.11, in hydrogen peroxide were observed. We found that the intravenous injection of at least 0.2 ml ether or 15 mg hydrogen peroxide was necessary to achieve effective echo enhancement of the myocardium in dogs.

Animals↗
PubMed1985

[The effects of intra-abdominal pressure on regional renal blood flow during peritoneal dialysis].

This experimental studies were designed to investigate the effects of intra-abdominal pressure (IAP) on renal regional blood flow and renal function during peritoneal dialysis (PD) for acute renal failure (ARF). The mongrel dogs were divided into four groups. Group I (n = 10): IAP of atmospheric pressure without PD (control group); Group II (n = 10): Intermittent PD with IAP of 10 mmHg; Group III (n = 10): Intermittent PD with IAP of 20 mmHg; Group IV (n = 10): Continuous PD with IAP of 3-5 mmHg. The following results were obtained. Significant decrease (p less than 0.01-0.05) of renal cortical blood flow (RCBF), total renal blood flow (TRBF), ratio of RCBF to renal medullar blood flow, renal perfusion pressure (RPP), cardiac index and urinary output, and increased renal vascular resistance and inferior vena caval pressure were observed in group III, but in group IV, values of these parameters returned to control level. The limit of influence to renal function was confirmed to be as follows. (1) IAP of 30 mmHg or more, (2) RPP of less than 65 mmHg, (3) TRBF of less than 2.2 ml/g/min, (4) and RCBF of less than 78 ml/100 g/min. These studies suggest that RPP are simple and excellent index to reflex renal hemodynamics, and the continuous PD are better procedure than the intermittent PD from a view of renal regional blood flow.

Abdomen↗
PubMed1984

Monoamine oxidase-containing neurons in the cat hypothalamus: distribution and ascending projection to the cerebral cortex.

Using a recently developed monoamine oxidase (MAO) histochemical technique, we show the existence of MAO-containing neurons in the cat hypothalamus. In conjunction with retrograde tracer technique with horseradish peroxidase, we further demonstrate that virtually all posterior hypothalamic neurons projecting directly to the occipital cortex contain MAO, an amine catabolizing enzyme.

Animals↗