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Biomedical subjects

T Machida

Publications and source records attributed to T Machida.

At least 289 records · Page 16Linked to original sources

[The development of determining human prostatic acid phosphatase by radioimmunoassay (author's transl)].

We purified human prostatic acid phosphatase (hPAP) from prostatic tissues by affinity chromatography, DEAE cellulose and gel filtration and also examined physicochemical properties of highly purified PAP. We developed a double-antibody radioimmunoassay for hPAP in serum, with use of antiserum raised in rabbit against highly purified PAP. The antiserum did not cross react with acid phosphatase from platelets and red blood cells. Experimental detail are outlined to assess the reproducibility and reliability of the method under various conditions. The upper limit of the serum PAP levels in the present assay was set at 3.0 ng/ml by 162 determinations of samples. The serum PAP levels of 2 untreated patients with prostatic carcinoma were higher than 3.0 ng/ml and 39 patients with benign prostatic hyperplasia were an average value of 1.9 ng/ml.

Acid Phosphatase↗

[Critical study on dead cases in recurrent early stomach cancer (author's transl)].

35 deaths of 299 operated early stomach cancers have been studied retrospectively. These cases can be grouped in the following categories: 2 deaths directly due to operation, 7 due to recurrence of carcinoma, 19 due to other diseases including cancer in other sites and 7 cases in which the real causes of death could not be elucidated. Special attention was paid on the 7 recurrent cases: In 4 of 7 patients the histological study revealed lymph and blood vessels invasion in their resected stomachs, lymphnodes metastases in 5 patients and positive cut-end in 2 patients. 5 of 7 patients died within 3 years after operation.

Adult↗

Operative and postoperative choledochofiberoscopy.

Choledochofiberoscopy is effective for both diagnosis and therapy. It is a valuable diagnostic technic because it permits a definite diagnosis and it allows the surgeon to determine the operative method by direct viewing and by biopsy of the biliary tract wall. Choledochofiberoscopy is therapeutically valuable because it permits cleaning of the bile duct, the removal of retained or remnant stones in the common and intrahepatic ducts, and the removal of granuloma and benign tumor with forceps under direct vision.

Biliary Tract Surgical Procedures↗