Search PubMed⌕ Search

Biomedical subjects

T Ma

Publications and source records attributed to T Ma.

168 records · Page 10Linked to original sources

COX-2 selective inhibitors and bone.

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed medications for relief of pain and inflammation. Recent animal studies using models of fracture healing and bone ingrowth suggest that NSAIDs (both non-selective NSAIDs and selective COX-2 inhibitors) adversely affect these bone-related processes. The dose and time-relationships of these medications and their resulting effects on bone have not yet been fully elucidated. Furthermore, whether COX-2 inhibitors and non-selective NSAIDs lead to clinically relevant adverse effects on bone healing in humans is unknown.

Animals↗

Comparison of interface relationships between implant components for laser-welded titanium frameworks and standard cast frameworks.

With the introduction of new techniques for the fabrication of frameworks for implant-supported prostheses comes the need to understand how the components used compare to those used for conventional cast frameworks. The relationship of measured machining tolerances between conventional implant components and those components used for stereo laser-welded implant frameworks was determined using a standardized protocol. Statistically significant differences in the horizontal interface relationship were found between paired implant components, which had a mean range from 23.1 to 51.7 microns. From a laboratory and clinical perspective, machining tolerances of implant components represent a variable associated with their manufacturing, which can ultimately affect the fit of a completed prosthesis.

Alloys↗

Accuracy of electronic implant torque controllers following time in clinical service.

Tightening of the screws in implant-supported restorations has been reported to be problematic, in that if the applied torque is too low, screw loosening occurs. If the torque is too high, then screw fracture can take place. Thus, accuracy of the torque driver is of the utmost importance. This study evaluated 4 new electronic torque drivers (controls) and 10 test electronic torque drivers, which had been in clinical service for a minimum of 5 years. Torque values of the test drivers were measured and were compared with the control values using a 1-way analysis of variance. Torque delivery accuracy was measured using a technique that simulated the clinical situation. In vivo, the torque driver turns the screw until the selected tightening torque is reached. In this laboratory experiment, an implant, along with an attached abutment and abutment gold screw, was held firmly in a Tohnichi torque gauge. Calibration accuracy for the Tohnichi is +/- 3% of the scale value. During torque measurement, the gold screw turned a minimum of 180 degrees before contact was made between the screw and abutment. Three torque values (10, 20, and 32 N-cm) were evaluated, at both high- and low-speed settings. The recorded torque measurements indicated that the 10 test electronic torque drivers maintained a torque delivery accuracy equivalent to the 4 new (unused) units. Judging from the torque output values obtained from the 10 test units, the clinical use of the electronic torque driver suggests that accuracy did not change significantly over the 5-year period of clinical service.

Analysis of Variance↗

Translucency parameter of colorants for maxillofacial prostheses.

The masking power of various generic, dry mineral earth, and flocking colorants dispersed in medical-grade silicone elastomer was investigated. Reflectance measurements were made by diffuse reflectance spectrophotometry using black and white backings. These data were reduced to optical scattering and absorption coefficients through the use of the Kubelka-Munk reflectance theory. The color difference between a 0.13-cm-thick layer of the colored elastomer placed on an ideal black backing and this layer on an ideal white backing was calculated and established as a translucency parameter. Using analysis of variance and stepwise comparison testing, significant differences were found among the translucency parameters of the colorants. Since these colorants differ substantially in their ability to mask underlying colors and since the translucency of maxillofacial material is an important aspect of color measurement and natural appearance, differences in these colorants go beyond their obvious differences in color.

Absorption↗

Fatigue life of preceramic soldered and postceramic soldered joints.

This research investigated the fatigue life (ie, the number of cycles of a given stress that can be sustained by a sample prior to catastrophic failure) of metal ceramic soldering. One metal ceramic alloy was joined using four postceramic solders and one preceramic solder. All specimens received appropriate heat treatment simulating ceramic application although no porcelain was applied. Five specimens were fabricated for each solder type, and a 35,000 psi (241.4 MPa) fatigue stress was applied to each solder joint during specimen testing. The test variable was the number of stress cycles required to fail each specimen. The postceramic solders exhibited significantly higher fatigue lives than did the preceramic solder. Scanning electron microscope analysis showed that the preceramic solder not only exhibited a larger grain size, but also showed micropores between these grains.

Analysis of Variance↗

Tolerance measurements of various implant components.

Machining tolerance, an intrinsic characteristic that exists between machined implant components, identifies the amount of horizontal shift possible between paired components. Machining tolerances between implant components (abutment, gold, cylinder, impression coping, and brass abutment replicas) were measured with a coordinate measuring machine. The measured tolerances ranged from 22 to 100 microns. Machining tolerances between implant components should be included in future studies of accuracy, because it is an inherent characteristic of the component itself.

Alloys↗