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Biomedical subjects

T M Moles

Publications and source records attributed to T M Moles.

8 recordsLinked to original sources
PubMed1999

Emergency medical services systems and HAZMAT major incidents.

Exposures to released hazardous materials (HAZMAT) pose an increasing threat to individual and public health, particularly in high population density. Any incident causing casualties on a scale which threaten or causes overload of the available resources of the emergency medical services (EMS) or associated systems (EMSS), constitutes a major incident (MI). Emergency services, including the EMSS, have a statutory duty to develop a comprehensive, integrated and flexible all-risk Major Incident Plan (MIP) for such an event. The MIP should also include developed management provision for HAZMAT incidents and in particular provision for safety and protection of both casualties and the EMSS personnel and systems, from secondary contamination by persistent, transmissible HAZMAT agents. This paper offers an outline review of contemporary policy and practice guidelines for the management of HAZMAT incidents and major incidents, with emphasis on the following: strategic and tactical preparation, integrated modular planning, communications, evaluation, training and equipment, including personal protection. In addition organisational aspects of the safe management and protection of the EMSS and personnel at the incident site, during transportation and at the receiving hospitals are considered. Safe and effective management of casualties requires adequate protection from further exposure, triage and synchronous decontamination and life support. Finally, the implications of conventional and unconventional conflict including terrorism and current unsolved problems are discussed.

Disaster Planning↗
PubMed1999

Clinical analogies for the management of toxic trauma.

The management of injuries from toxic release (HAZMAT) incidents is unfamiliar to many emergency medical responders owing to the relative rarity of such incidents. However, the risks from toxic release in both industrial and other metropolitan areas are increasing and emergency medical services (EMS) personnel should be trained to be aware of the dangers to both victims and responders alike. Many examples exist of analogies for the management of HAZMAT situations from conventional prehospital and hospital emergency medicine. Application of the lessons learned in more familiar situations will be of benefit for the preparation of an effective EMS response for HAZMAT.

Disasters↗
PubMed1987

A comparison of the incidence and nature of cardiac dysrhythmias occurring during enflurane and isoflurane anaesthesia for dental surgery.

The incidence and nature of dysrhythmias with equipotent concentrations of enflurane and isoflurane during dental surgery were compared. Seventy-six Chinese patients between 17-30 years, of ASA Grade I, randomly received either enflurane or isoflurane with N2O and O2 for spontaneous ventilation during third molar extractions. The cardiac rhythm and the blood pressure were continuously monitored during the procedure. The incidence of dysrhythmias with both enflurane and isoflurane was low and the difference not statistically significant. During surgery one patient exhibited unifocal ventricular ectopics with isoflurane. Sinus tachycardia was common with both agents. No life-threatening dysrhythmias were seen with either agent and no clinically significant lowering of blood pressure occurred in association with the exhibited dysrhythmias. In this Chinese population, as in other studies, the incidence of dysrhythmias with both agents was low thus showing no difference between the races.

Adolescent↗
PubMed1986

Comparison of the incidence and nature of cardiac arrhythmias occurring during isoflurane or halothane anaesthesia. Studies during dental surgery.

Seventy-six Chinese patients aged between 15 and 30 yr, undergoing 3rd molar extraction, were randomly allocated to two groups. One group received halothane and the other isoflurane. The incidence of arrhythmia during surgery under anaesthesia with isoflurane was significantly less than with halothane. Sinus tachycardia was a significant feature under anaesthesia with isoflurane. Under anaesthesia with halothane, the arrhythmias occurring most frequently during surgery were ventricular ectopics, the commonest being ventricular bigeminy. The frequency and nature of arrhythmias during surgery on right and left sides were similar. In three patients a slight decrease in arterial pressure was recorded in association with the arrhythmia, but on stopping the stimulus, both rhythm and arterial pressure returned to normal. The incidence of arrhythmia with halothane in the Chinese population in this study was significantly higher than that reported previously in non-Chinese patients.

Adolescent↗
PubMed1975

Controlled prospective study of the effect on liver function of multiple exposures to halothane.

Patients who had received halothane within a periof of one year and who required another anaesthetic were allocated at random to be given halothane or a control anaesthetic, the control being fiben using halothane-free apparatus. There were 76 patients entries in each group. Serum-glutamic-oxaloacetic-transaminase (S.G.O.T.) levels were measured before the anaesthetics and serially postoperatively for two to three weeks. The S.G.O.T. levels in the halothane group were significantly higher than in the controls. High levels were confined to patients who had had less than four previous halothane anaesthetics, increases above normal in the remainder and in the controls being rate. 1 patient in the halothane group had an S.G.O.T. of 440 I.U. per litre and hepatocellular necrosis on liver biopsy. 2 patients in the halothane group whose S.G.O.T.s rose to more than twice normal showed a similar reaction to re-exposure to halothane, although they had not shown a reaction to an intervening control anaesthetic.

Aged↗
PubMedDate not supplied

Toxic trauma.

Hazardous materials (HAZMAT) carry many inherent dangers. Such materials are distributed widely in industrial and military sites. Toxic trauma (TT) denotes the complex of systemic and organ injury caused by toxic agents. Often, TT is associated with other injuries that also require the application of life-support techniques. Rapid onset of acute respiratory failure and consequent cardiovascular failure are of primary concern. Management of TT casualties is dependent upon the characteristics of the toxic agents involved and on the demographics surrounding the HAZMAT incident. Agents that can produce TT possess two pairs of salient characteristics: (1) causality (toxicity and latency), and (2) EMS system (persistency and transmissibility). Two characteristics of presentations are important: (1) incident presentation, and (2) casualty presentation. In addition, many of these agents complicate the processes associated with anaesthesia and must be dealt with. Failure of recognition of these factors may result in the development of respiratory distress syndromes and multiorgan system failure, or even death.

Causality↗