Subcutaneous suture placement.
Explore the source record for details and available documents.
Dermatologic Surgical Procedures↗
Biomedical subjects
T M Davidson
Publications and source records attributed to T M Davidson.
Evaluation and treatment of smell dysfunction.
We gave 63 patients with symptoms of smell dysfunction a full evaluation by age-adjusted olfactory threshold and odor identification testing, rhinomanometry, nasal cytology, nasal endoscopy, computed tomographic (CT) scan and a trial of medical treatment. CT scans were valuable for identifying ethmoid sinus disease and nasal endoscopy for inspecting olfactory epithelium. A trial of prednisone served as a diagnostic modality to identify correctable causes of smell dysfunction. Given that there are 2 million people in the United States with a smell dysfunction, that the average physician knows little about its diagnosis and treatment and that the psychosocial impact to an afflicted person is great, we urge a greater awareness of smell dysfunction, its diagnosis and its treatment.
Adult↗
Pasteurella infections of the head and neck.
Infections caused by Pasteurella occur most frequently after domestic animal bites or scratches and in individuals with agricultural or veterinary contact with animals. A serious Pasteurella infection developed in an agricultural worker following tumor extirpation of a head and neck neoplasm. Review of Pasteurella infections in humans disclosed that 31 of 446 reported infections involved head and neck structures. The most serious of these involved the adjacent central nervous system. Surgical drainage combined with parenteral penicillin remains the treatment of choice in these infections. Aminoglycosides are not effective in treating this organism.
Anti-Bacterial Agents↗
Artificial eardrum for instruction in myringotomy and PE tube insertion.
Explore the source record for details and available documents.
Humans↗
Intermittent tracheostomy in sheep.
A modified tracheostomy was designed for respiratory function studies in sheep. Our primary objective was to prevent development of severe tracheal stenosis, which was observed with procedures designed for canine tracheostomy. Surgery consisted of an intercartilaginous tracheal slit, with apposition of tracheal mucosa to skin. This procedure produced no significant stenosis at postmortem evaluation in 19 sheep. In contrast, 5 of 20 sheep with excision of the ventral 1/3 of the third and fourth tracheal rings, had severe tracheal stenosis.
Animals↗
The biology of head and neck cancer. Detection and control by parallel histologic sections.
Microscopic fingers of epidermoid cancer can extend submucosally 1 to 3 cm from grossly discernible borders of upper aerodigestive tract cancers. These fingers are best detected by sectioning all surgical margins parallel to the margins. Microscopic disease was found at the original excisional margins in 75% of 70 cases. Using this principle for frozen-section evaluation, and reexcising further tissue as indicated, local disease was completely controlled in all 24 patients eligible for two-year follow-up.
Carcinoma, Squamous Cell↗
In vitro biaxial stress-strain response of human skin.
The development of new experimental methods and test equipment has permitted a study of the mechanical characteristics of unembalmed human cadaver skin. Excised tissue specimens were exposed to dynamic, biaxially applied displacements and forces in order to quantify the skin's anisotropic, viscoelastic stress-strain response. In addition to monotonically increasing displacement-time loadings, experiments were performed to measure the tissue's stress relaxation characteristics resulting from a suddenly applied displacement. Data are presented that demonstrate a nonlinear stress-strain relationship for the skin that is notably influenced by displacement boundary conditions imposed on the tissue specimen. Results indicate that the skin is a viscoelastic material whose mechanical loading response is dependent on the anatomic direction in which the strains are applied.
Abdomen↗
Cochlear deoxyglucose uptake: relationship to stimulus intensity.
The relationship between stimulus intensity and the uptake of 2-deoxyglucose (2-DG) in the cochlea of the gerbil was studied using an autoradiographic technique. In silence, incorporation of labeled 2-DG into stria vascularis and the spiral ligament was significantly higher than for other inner ear structures. With increasing intensity of noise exposure, 2-DG uptake in the spiral ganglion and VIIIth nerve increased dramatically when compared to the lateral wall structures. In contrast, relative 2-DG uptake in the organ of Corti was much less affected by noise exposure. Only at 105 dB SPL, the highest intensity tested, was a modest but statistically significant increase observed in the sensory epithelium. The small change in relative 2-DG uptake observed in the organ of Corti during acoustic stimulation is consistent with Davis' (1965: Quant. Biol. 30, 181-190) battery model of the cochlear transduction process. Alternatively, a larger change may have occurred, but been restricted to a small portion of the epithelium, such as one or both populations of hair cells.
Acoustic Stimulation↗
Hyoid bone elevation: a sign of tracheal transection.
Evaluation of traumatic neck injuries should include analysis of the position of the hyoid bone on the lateral radiograph. Location above the level of the third cervical body or a greater cornu located less than 2 cm from the angle of the mandible, or both, coupled with the finding of cervical soft-tissue air, should alert the radiologist that tracheal transection is likely and that immediate surgical exploration is required. Five cases of severe neck injury are presented.
Adolescent↗
Cochlear and middle ear effects on metabolism in the central auditory pathway during silence: a 2-deoxyglucose study.
Explore the source record for details and available documents.
Acoustic Stimulation↗
Evaluation and treatment of congenital facial paralysis.
An approach to the evaluation and the preferred methods of treatment of congenital facial paralysis is presented. The expected results from testing procedures and the limitations of their usefulness in acquired v developmental palsies are discussed. We recommend that the auditory brain-stem response test be included in the initial evaluation of patients with congenital facial paralysis.
Adolescent↗
Effectiveness of curettage and electrodesiccation in the removal of basal cell carcinoma.
Basal cell carcinomas are slow-growing malignant skin tumors which have traditionally been successfully treated by curettage and electrodesiccation. Curettage and electrodesiccation is traditionally repeated two or three times, but there are no previous studies documenting the value for the repetitions. This study compares the efficacy of curettage and desiccation once and three times in removing basal cell tumors. The results suggest that these neoplasms have two distinct growth patterns. One is more invasive and incompletely removed by curettage-desiccation. The second pattern is removed by a single cycle of curettage and desiccation. It is hypothesized, based on a review of pertinent literature, that these growth patterns are related to immunologic interaction with tumor cells.
Basal Cell Carcinoma↗
Fatal epistaxis in craniofacial trauma.
Facial trauma often results in minor and infrequently results in major bleeding in the structures of the face. We have recently observed two patients who suffered fatal hemorrhages which could have been controlled using relatively simple measures. Treating physicians often overlook this serious and potentially life-threatening source of hemorrhage until the patient has been in shock for long periods of time and irreversible ischemic brain damage and renal failure have occurred. With careful attention to examination of the face and oropharynx, hemorrhage from these sites can be identified early and the appropriate measures taken to control epistaxis.
Adolescent↗
Surgery for nasal obstruction--evaluation by rhinomanometry.
Nasal obstruction is predominantly a subjective patient complaint. The physical examination of the nose for nasal obstruction is a subjective evaluation as well. While the history and physical examination are reasonable diagnostic indicators, an objective means of evaluation is needed. Rhinomanometry measures nasal obstruction objectively and reliably. Thirty-six patients with nasal obstruction were evaluated by rhinomanometry before and after nasal surgery. The results are reported here. Rhinomanometry confirms the effectiveness of intranasal surgery. Using rhinomanometry, various techniques of intranasal surgery are evaluated, and several interesting observations are made.
Adolescent↗
Tip suspension suture for superior tip rotation in rhinoplasty.
Superior tip rotation is sometimes necessary to relieve functional obstruction as well as improve the esthetic appearance in the aging nose and the thick skinned heavy tip nose. Conventional techniques including thinning resection, rim strip, lateral crural flap and even external skin excisions are often inadequate to obtain and maintain sufficient superior tip rotation. A technique is described to permanently suture the lower lateral crus to the upper lateral cartilages and to the cartilaginous septum. Long-term follow-up supports this technique's cosmetic and functional effectiveness.
Humans↗
Anesthesia in septorhinoplasty. Effects of halothane vs nitrous oxide narcotic on bleeding.
The effects of halothane and nitrous oxide narcotic anesthesia on bleeding were studied. Coagulation parameters were examined preoperatively and a half hour after induction. There were no notable changes with either anesthetic technique, and there were no substantial differences between the two anesthesias. A clinical comparison of bleeding, surgical exposure, blood pressure, and duration of surgery also was made. The two anesthetic techniques tested had no notable differences in the previously mentioned parameters on septorhinoplasty.
Adult↗
Bleomycin, cyclophosphamide and radiotherapy in regionally advanced epidermoid carcinoma of the head and neck.
We have treated 24 patients with squamous carcinoma of the head and neck and advanced regional (N2-3) disease. The regimen consisted of 3 cycles, each of 28 days. Cyclophosphamide (1 gm/m2 I.V.) was given on day 1, bleomycin (15 u I.M.) on days 2, 4, 9 and 11, and ionizing radiation (60Co, 180 rad/fraction) days 1-5, and 8-12. No therapy was given on days 13-28. After three cycles of therapy, 13 patients had a complete response; following further therapy (surgery, interstitial or external beam radiation), 16 patients were free of disease. However, remissions were not durable and 11/16 patients recurred loco-regionally with a median time to recurrence of 5 months; most (7/11 also developed distant metastases. These patients have biologically aggressive disease and may have a worse prognosis than patients who are Stage IV based on a T4 primary lesion only.
Bleomycin↗
Applications of the biomechanical behavior of cartilage to nasal septoplastic surgery.
The biomechanics of septal cartilage as they apply to septoplasty are studied. The original investigations on septal cartilage are reviewed and summarized. Biomechanical principles of the behavior of cartilage are reviewed and applied to the principles of septoplasty surgery. Using pigs' ears, theoretical predictions are investigated and verified. Incorporating this information, an approach to septoplastic surgery is described.
Adolescent↗