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Biomedical subjects

T Lindholm

Publications and source records attributed to T Lindholm.

At least 73 records · Page 4Linked to original sources
PubMed1979

The influence of vitamin B6 supplementation on the bone marrow morphology in patients on regular haemodialysis treatment. A double-blind study.

Bone marrow smears from 20 patients with chronic renal failure and on regular haemodialysis treatment (RDT) were morphologically analysed. A double-blind study of treatment with high doses of vitamin B6 showed that the patients receiving pyridoxine got raising frequencies of lymphocytes and monocytes in the bone marrow and there were morphologic signs of a normalization within the granulopoiesis. It is suggested that this is a sign of an enhancement of the immune response. The vitamin supplementation had no significant effects on the pronounced anemia of the patients.

Adult↗
PubMed1978

Secondary hyperparathyroidism combined with uremia and giant cell containing tumor of the cervical spine. A case report.

A 47-year-old woman with chronic pyelonephritis since 1950 was prepared for hemodialysis or kidney transplantation. Investigation disclosed secondary hyperparathyroidism and an osteolytic lesion in C VII and Th I causing a subluxation. There were minor neurological symptoms and apparent risk of luxation of the cervical spine with resulting injury to the spinal cord. Operation was performed with total parathyroidectomy and excision of the bone tumor, followed by fixation of the cervical spine with bone graft. There were no major complications during the postoperative period and the patient was mobilized four months after the operation.

Cervical Vertebrae↗
PubMed1977

Blood transfusion and kidney transplantation.

During the years 1968--1976, 115 nondiabetic primary cadaveric transplantations were performed in southern Sweden. For 95 of these patients there was an observation period of at least one year. 32% of these patients had never received a blood transfusion. These recipients had an lower one year graft survival (33%) than those who had received one or more transfusions (48%). Patients who had received more than five transfusions did not show a higher graft survival than other transfused kidney recipients. Presence of cytotoxic antibodies also decreased the one year graft survival both in the transfused and not transfused patient groups.

Antibodies↗
PubMed1976

Effect of splenectomy on anemia in patients on regular dialysis treatment.

Splenectomy was performed in 7 patients on regular hemodialysis treatment who had disabling anemia. All patients had a short 51Cr red cell survival time and an increased splenic uptake of red cells verified by external counting and computer-aided scintigraphy. The need for blood-transfusions was eliminated in all except one. In all patients the hemoglobin concentration rose after splenectomy. This was probably an effect of a reduced plasma volume and the removal of a large pool of non-circulating red cells. No consistent changes in the red blood cell survival time or the red cell volume were observed. The white cell and the platelet counts in the blood rose to twice the preoperative value. No adverse effect of the splenectomy was observed.

Adolescent↗
PubMed1976

Lymphocele: an important post-transplantation complication.

Four cases of perirenal lymphocele after transplantation are reported. The possible aetiology, symptoms, and diagnosis of this uncommon complication are discussed. Careful dissection and ligation of perivascular lymph vessels during transplantation are recommended.

Adult↗
PubMed1975

The relationship between hepatitis B antigen, e-antigen, and liver-pathology in patients treated with dialysis.

The relationship between hepatitis B antigen (HB Ag), e-antigen and liver pathology was studied in 27 patients who had died after regular dialysis treatment. The examination of the liver histology was done without knowledge of the history of the patient. Seventeen of the patients were HB Ag positive at death and had been carriers of the antigen for between 1 and 57 months. Two had chronic aggressive hepatitis and 10 chronic persistent hepatitis, but 5 had no histological signs of chronic hepatitis. e-antigen could be found in blood samples from all these patients. The cause of kidney disease, duration of dialysis and time of carriership of HB Ag showed the same variation among the patients without as among the patients with signs of chronic hepatitis. Two patients who had been HB Ag positive but were negative at death had no signs of chronic hepatitis. HB Ag positive samples available from one of these patients were also positive for e-antigen. Eight patients who were constantly negative for HB Ag were also negative for e-antigen. One of them had autopsy findings of a chronic persistent hepatitis. There were thus very moderate or even no histological signs of chronic hepatitis among these patients in spite of prolonged carriership of HB Ag. A very close correlation between HB Ag and e-antigen was also found.

Antigens↗
PubMed1975

Pyelocystostomy used as a treatment of ureteric necrosis after kidney transplantation.

A 32-year-old male had chronic glomerulonephritis and terminal renal failure. He was treated with intermittent haemodialysis, and transplantation of a cadaveric kidney. Urine extravasation occurred due to ureteric necrosis. He was treated with temporary diversionary ureterostomy, and 9 weeks later a direct anastomosis between the pelvis of the transplanted kidney and the recipient bladder was performed. Thirty-three months after this operation the transplanted kidney is functioning well.

Adult↗