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Biomedical subjects

T L Woodings

Publications and source records attributed to T L Woodings.

12 recordsLinked to original sources
PubMed1983

The effect of estrogen receptor status on survival in patients with endometrial cancer.

This study demonstrates a significantly increased survival time for women with estrogen receptor-positive adenocarcinoma of the endometrium when compared with that of those with estrogen receptor-negative tumors (p less than 0.05). This prognostic factor provides information which is additional to, and independent of, that provided by the histologic grade and myometrial penetration of the tumor.

Adenocarcinoma↗
PubMed1982

Suicide during 1961-70 migrants in Australia.

Rates and methods of suicide during 1961-70 migrants in Australia were compared with native born Australians. Large differences in both rates and methods of suicide were found in individual migrant groups. The rates were more akin to those in the country of origin than of the Australian-born, no matter how long the migrants had lived in Australia. By contrast, methods of suicide use by migrants approached more closely those of the Australian-born the longer they had lived in Australia. The change in methods used was greater in those migrant groups coming from countries with a language and culture more akin to those in Australia. A discussion follows of various possible sociological and cultural factors, both within the countries of origin and within Australia, which could have contributed to these results.

Acculturation↗
PubMed1982

The relationship between suicide, undetermined deaths and accidental deaths in the Australian born and migrants in Australia.

Australian data pertaining to Suicide and Accidental Deaths (I.C.D.7) for the years 1962-69 are compared with those for suicide, undetermined deaths and accidental deaths (I.C.D.8) for 1968-71, specific for country of birth. The data strongly suggest that deaths classified as 'undetermined' after the introduction of that I.C.D. category in 1968, had been classified as accidental prior to that data, especially deaths from poisoning. There was some differential between the Australian and U.K. born and the European born. It was estimated that Australian suicide rates are possibly underestimated by 5-10% for males, and 10-20% for females by categorising some deaths from poisoning as being undetermined or accidental.

Accidents↗
PubMed1981

A 13-year follow-up of social drinkers.

In 1965-66 we examined 359 men in the workforce reporting an alcohol consumption ranging from nil to the equivalent of 11.4 L of beer a day. We found an association between reported drinking and the prevalence of hypertension and gout. Thirteen years later, we were able to trace 340 of these men; 39 of them had died. Survival curves showed that the heavier drinkers (those drinking more than: 1.14 L of beer a day) tended to die at an earlier age. Due to the relatively small numbers involved, the difference in mortality between the lighter and heavier drinkers was not statistically significant. We found no support for the theory that alcohol consumption affords protection against death from coronary heart disease.

Actuarial Analysis↗
PubMed1980

Patterns of gastro-intestinal cancer in European migrants to Australia: the role of dietary change.

Cancers of the stomach, pancreas, colon and rectum are increasingly regarded as being diet-influenced. Migrants to Australia from England, Scotland, Ireland, Poland, Yugoslavia, Greece, and Italy have come from countries with varied dietary backgrounds and gastrointestinal cancer risks. Age-standardized cancer death rates in migrrants, by country of origin, sex, age, and duration of residence in Australia (less than or equal to 16 years and greater than 16 years), have been calculated for 1962-76, and compared with those of the Australian-born population. All seven migrant source countries, in 1970, had higher rates of stomach cancer than Australia, and the corresponding migrants groups, which initially reflected those higher rates, experienced an approximately 25% risk reduction with increased duration of residence. For cancer of the pancreas, migrants initially had rates well above their "native" rates; with longer stay, the risks generally converged upon that of the Australian-born population. The four "continental" (European) migrant groups, whose native risk of colon cancer is about half that of the Australian population, showed an increased risk with increasing duration of stay. The increase was greater in men than in women, perhaps reflecting their greater dietary acculturation. By contrast, Scottish migrants, with an initially high risk of cigrants showed even larger increases than colon cancer, while in British migrants there was a marked decline towards the "Australian-borne" risk. These various changes in cancer risk are discussed with reference to inter-country dietary differences.

Adolescent↗
PubMed1978

Clinical trial experience by simulation: a workshop report.

A new computer program for experimental design simulation was used in a three-day postgraduate workshop on clinical trials. Participants were given information on a fictitious new drug and asked to design a trial to evaluate it. On the first day they reviewed the data and designed a protocol, and results for these specifications were generated on the computer. The second day was spent analysing results, and on the last day the findings of the different studies were presented at a symposium. Flexibility of the program ensured a high degree of realism in all trials and emphasised the influence of design on results and conclusions.

Adolescent↗
PubMed1978

Estimation of Michaelis--Menten constants in microsomal enzyme systems by the direct linear plot and least squares regression.

1. Data from in vitro liver microsomal metabolism of ethylmorphine aniline and benzpyrene in male rats and male and female quokkas (Setonix Brachyurus) were fitted to the Michaelis--Menten equation by Wilkinson's non-linear regression procedure and Eisenthal and Cornish-Bowden's direct linear plot. 2. Ethylmorphine and aniline metabolism in the male quokka were non-ideal, but in all other instances there were no differences in the performance of the two methods.

Aniline Compounds↗
PubMed1977

Computerised tomography of the cranium in patients with epilepsy: a preliminary report.

The findings are presented in 366 patients with seizures who were studied by computerised tomography of the cranium. The relative frequency of normal scans, cerebral tumours, atrophy and other pathological lesions is indicated. A more detailed analysis of the group of patients with atrophy was carried out. The frequency and severity of atrophy correlated significantly with age but not with length of seizure history. However, the more marked degrees of atrophy were found among patients with long-standing or poorly controlled epilepsy, an observation which has important implications with regard to the adequacy of seizure control in epileptic patients.

Adolescent↗
PubMed1976

Acute myocardial infarction: one year follow-up of 1138 cases from the Perth Community Coronary Register.

The one year mortality of patients from the Perth Acute Myocardial Infarction Register surviving the acute episode (first 28 days) is presented. Of 1138 patients suffering definite or possible acute myocardial infarction in one year, 705 (62%) survived 28 days. There were 89 deaths (11-5%) in the subsequent 11 months. One year mortality was related to age but not sex, previous symptoms of coronary heart disease, but not hypertension or diabetes, to tachycardia and congestive cardiac failure at first examination, but not arrhythmias in the acute episode. These observations highlight the importance of protecting the myocardium in the acute phase of myocardial infarction.

Acute Disease↗
PubMed1975

Immunity in colonic tumor patients after operation: determination by leukocyte-migration inhibition.

Tumor immunity in 31 colonic tumor patients was studied by determining in vitro leukocyte-migration inhibition. In tissue culture 30 per cent inhibition of patient leukocyte migration by tumor antigen could be demonstrated in half of the patients, suggesting that they were immune. This immunity was not related to the clinical or pathologic stage of the disease and varied in different patients. It was transient in some and persistent in others. In addition, a positive response at a fixed time after operation was not found.

Adenocarcinoma↗