Search PubMed⌕ Search

Biomedical subjects

T L Seahorn

Publications and source records attributed to T L Seahorn.

32 records · Page 2Linked to original sources
PubMed1993

Summer pasture-associated obstructive pulmonary disease in horses: 21 cases (1983-1991).

Medical records of 21 horses with summer pasture-associated obstructive pulmonary disease were reviewed, and history, signalment, clinical signs, radiographic signs, clinicopathologic data, and therapeutic response were determined. Most affected horses were used as pleasure horses, and for the most part, remained at pasture when not in use. The mean age (+/- SD) was 13.7 +/- 3.6 years. Clinical signs included intermittent nasal discharge, cough, tachypnea, labored expiratory effort, and crackles and wheezes on auscultation. Radiography frequently revealed interstitial patterns in the lung fields; in horses with chronic disease, pulmonary overinflation was evident. Hemogram was usually normal, and transtracheal wash fluid was characterized by nondegenerate neutrophils.

Age Factors↗
PubMed1993

Miscellaneous conditions of the equine head.

Nutritional secondary hyperparathyroidism is associated with horses that are fed diets with an imbalance of calcium and phosphorus or diets containing oxalates. Clinical signs include a shifting lameness, with tenderness of the joints, reluctance to move, or a stiff, stilted gait. Some horses may have broadening of the nasal bones, enlargement of the maxilla and/or the mandible, or a ridge over the nasal bones. Diagnosis may include physical examination findings; analysis of feed; and clinical pathologic data, which may include normocalcemia, normal to increased serum phosphorus, and increased fractional excretion of phosphorus (normal FxP < 0.5%). The primary objective of therapy is to correct the nutritional calcium to phosphorus imbalance. Sialoliths are calcific concretions that develop in the salivary gland or duct. Therapy generally involves surgical removal, and associated complications are uncommon. Obstruction of the nasolacrimal duct occurs most commonly secondary to intraluminal foreign material, although congenital atresia may occur. Clinical signs include epiphora, conjunctivitis, and mucopurulent discharge. Foreign material is often removed by retrograde saline flush and atresia is resolved by surgery.

Animals↗
PubMed1992

Ultrasonographic imaging of a keratoma in a horse.

Ultrasonography was used to confirm the tentative diagnosis of keratoma in a horse admitted for chronic progressive lameness. A definitive diagnosis of keratoma traditionally has been diagnosed by history, clinical findings, and radiographic evaluation. Confirmation of the keratoma by use of ultrasonography facilitated the formulation of a treatment plan that resolved the condition.

Animals↗
PubMed1992

Mammary adenocarcinoma in four mares.

Mammary gland adenocarcinoma in 4 horses was characterized by firm swelling of the gland and serosanguineous discharge from the teat orifice. Two of the mares had ulcerative lesions of the mammary gland. Palpation of the affected gland typically elicited signs of pain. Diagnosis was assisted by cytologic evaluation of the fluid discharge, but definitive diagnosis was based on histologic examination. Treatment included mastectomy and lymphadenectomy.

Adenocarcinoma↗
PubMed1991

Nonsurgical removal of chondroid masses from the guttural pouches of two horses.

Chondroid masses were successfully removed from the guttural pouches of 2 horses, using an endoscope, a snare, and a vacuum pump. This technique is an alternative to surgical removal of chondroid masses in patients when basic lavage of the affected guttural pouch is ineffective. Complications were not encountered. Advantages of this snare technique include avoidance of surgery and its potential complications, minimal recovery time, and minimal expense.

Animals↗
PubMed1991

Cystic nasal concha in a calf.

Unilateral cystic nasal concha was diagnosed in a 6-month-old Brangus male calf by use of endoscopy, radiography, and histologic examination. Cystic nasal conchae have been excised via dorsolateral rhinotomy, but the lesion in the calf of this report was excised transnasally, with considerable ease, using obstetric wire. Postoperative complications did not develop, and the calf was reportedly in good health 3 months after discharge.

Animals↗
PubMed1990

Cardiac arrhythmias identified in horses with duodenitis/proximal jejunitis: six cases (1985-1988).

During a 3 1/2-year period, cardiac arrhythmias were identified in 6 of 67 horses diagnosed with duodenitis/proximal jejunitis (DPJ). Arrhythmias were detected by auscultation of irregular cardiac rhythm and subsequently were characterized by electrocardiographic evaluation. Arrhythmias included frequent second-degree atrioventricular block, ventricular ectopic depolarizations, and atrioventricular conduction disturbance. In 4 horses, arrhythmias resolved with recovery from the primary problem. One horse died suddenly 66 hours after admission, and another was euthanatized at 72 hours after admission. Clinical and laboratory data from horses with DPJ and cardiac arrhythmias (group 1) were compared with findings for horses with DPJ and without arrhythmias (group 2). Group-1 horses had significantly (P less than 0.05) higher serum bicarbonate concentration and serum creatine kinase activity. Normal sinus rhythm returned in all 4 group-1 horses that recovered from DPJ, suggesting a causal relationship between DPJ and the arrhythmias. Two group-1 horses were necropsied, and both had myocarditis. The cause of these lesions was not determined.

Animals↗
PubMed1990

Effects of human alpha interferon on experimentally induced equine herpesvirus-1 infection in horses.

The immunotherapeutic effect of low-dose human alpha interferon on viral shedding and clinical disease was evaluated in horses inoculated with equine herpesvirus-1 (EHV-1). Eighteen clinically healthy weanling horses, 5 to 7 months old, were allotted to 3 equal groups. Two groups were treated orally with human alpha-2a interferon (0.22 or 2.2 U/kg of body weight), on days 2 and 1 before inoculation with EHV-1, the day of inoculation, and again on postinoculation day 1. The horses of the remaining group were given a placebo orally on the same days. The horses were monitored daily for changes in body temperature and for clinical signs of respiratory tract disease. Blood and nasal swab specimens were collected daily for virus isolation. Blood was also collected at intervals throughout the monitoring period for evaluation of CBC, serum IgG and IgM concentrations, and antibody titers to EHV-1. Febrile responses, nasal discharge, viral shedding, changes in CBC, and an increase in antibody titers to EHV-1 were noticed in all horses after inoculation. There was no significant difference (P greater than 0.05) in mean values of the factors measured between treatment and control groups.

Animals↗
PubMed1989

Erysipelothrix rhusiopathiae bacteremia in a horse.

Erysipelothrix rhusiopathiae serotype 5 was isolated from blood obtained antemortem from a horse with presenting problems of laminitis, uveitis, acute blindness, localized ventral edema and depression. The patient failed to respond to therapy and died 96 hours after the onset of clinical signs. Cultures of the lung postmortem yielded Erysipelothrix rhusiopathiae serotype 5, Beta-hemolytic Streptococcus sp., Escherichia coli, Proteus sp., and Klebsiella sp.

Animals↗
PubMedDate not supplied

Evaluation of an autologous tendon graft repair method for gap healing of the deep digital flexor tendon in horses.

A sutured tenorrhaphy technique that incorporated an autologous tendon graft was compared mechanically and histologically with a sutured tenorrhaphy at 6, 12, and 24 weeks after repair. Tenorrhaphy was performed in the forelimb tendon of the deep digital flexor muscle and the graft was taken from the hindlimb tendon of the lateral digital extensor muscle; one forelimb site included the graft, whereas the other forelimb site was not grafted. Tenotomies were made immediately proximal to the insertion of the accessory ligament into the tendon of the deep digital flexor muscle. Grafted and nongrafted tenorrhaphies were sutured with 2 polydioxanone in a modified double locking-loop pattern. Limbs were supported with a bandage and an extended elevated heel shoe that maintained the dorsal hoof wall angle at 70 degrees to 75 degrees; this support was removed at 12 weeks and dorsal hoof wall angle was maintained at 40 degrees to 45 degrees for the remainder of the study. Gap formation (2.5 +/- .3 cm) was evident at all tenorrhaphy sites at 3 days on ultrasound examination. In grafted repairs, the breaking stress was increased (P < .001) between 6 weeks (2.56 +/- .44 MPa) and 12 weeks (17.69 +/- 7.68 MPa), with grafted tendon having a greater breaking stress than nongrafted tendon (8.77 +/- 2.5 MPa; P < .05). No differences in breaking stress were evident at 24 weeks. At 12 weeks, repair tissue in grafted tendon was histologically more mature, had less cellularity, better fibroblast orientation and more homogeneous collagen matrix than nongrafted tendon. Polydioxanone suture was still evident histologically at 24 weeks and was associated with minimal cellular reaction. Incorporation of an autologous tendon graft improved the mechanical properties and histological quality of the repair tissue in equine flexor tenorrhaphies at 12 weeks but not at 24 weeks after repair.

Animals↗
PubMedDate not supplied

Ultrasound-assisted diagnosis of renal dysplasia in a 3-month-old Quarter Horse colt.

A 3-month-old foal was presented for correction of bilateral angular limb deformities. Azotemia was detected as an incidental finding. Small, misshapened, hyperechoic kidneys with decreased corticomedullary demarcation were noted with ultrasonography. Additionally, the internal renal architecture was abnormal in that the intrarenal vessels and distant collecting system were not clearly seen in either kidney. Ultrasound-guided renal biopsy was suggestive of congenital renal dysplasia, which was later confirmed at necropsy. Clinical, sonographic, and pathologic features of equine renal dysplasia are discussed.

Animals↗
PubMedDate not supplied

Chronic renal failure associated with nephrolithiasis, ureterolithiasis, and renal dysplasia in a 2-year-old quarter horse gelding.

A 2-year-old quarter horse gelding presented for evaluation of polyuria and polydipsia. Azotemia was detected on serum chemistry profile. Small, misshapen, hyperechoic kidneys with decreased corticomedullary demarcation, hydronephrosis, and a right nephrolith were noted ultrasonographically. The diagnosis of end-stage kidney disease and dysplasia was made histopathologically using ultrasound-guided biopsy. Two ureteroliths were found in the right ureter via cystoscopy, and a nephrolith was seen in the right kidney at necropsy. Clinical, ultrasonographic, and pathologic features of equine urolithiasis and renal dysplasia are discussed.

Animals↗
PubMedDate not supplied

Prognostic indicators for horses with duodenitis-proximal jejunitis. 75 horses (1985-1989).

The medical records of 75 horses with duodenitis-proximal jejunitis (DPJ) were reviewed. Ages, physical parameters, laboratory values, and treatment data were compared between horses surviving DPJ and horses not surviving DPJ (Table 1). Fifty of 75 horses (66.6%) survived. Sixty-six horses (88.0%) were managed with medical treatment alone and nine horses (12.0%) were managed with medical treatment plus surgical intervention. Using a logistic regression model, the association of each of the 19 physical and laboratory parameters with death was evaluated retrospectively in the 75 horses. Three parameters (anion gap, abdominal fluid total protein concentration, and volume of gastric fluid for the first 24 hours of hospitalization) were significantly associated with death by univariate analysis. Using a stepwise multiple logistic regression, two parameters remained significantly associated with death (P < 0.05), anion gap and abdominal fluid total protein concentration.

Animals↗