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Biomedical subjects

T L Liu

Publications and source records attributed to T L Liu.

33 records · Page 2Linked to original sources
PubMed1984

Lymphocyte subsets in endometriosis.

Recent investigations suggested a possible immunologic etiology for endometriosis. To determine whether cellular immunity may be affected in patients with endometriosis, peripheral lymphocyte populations were investigated in 31 confirmed endometriosis patients and 22 control patients. No statistical differences in OKT3, OKT4, OKT8, OKM1, and OKTa1 cells could be observed. Total lymphocyte numbers were within normal ranges for both groups. Helper/suppressor ratios were not statistically different and were in a normal range for both groups. It is concluded that numeric differences in lymphocyte subpopulations represent only a very unlikely contributing factor in a potential immunologic etiology of endometriosis.

Antibodies, Monoclonal↗
PubMed1983

Cerebral metastatic choriocarcinoma in the People's Republic of China.

Thirty-four patients with cerebral metastases from choriocarcinoma were treated between 1964 and 1978 by the Department of Gynecology of the Tumor Hospital Chung Shan Medical College, Kwongchow, People's Republic of China. Disease in 20.5% (7 of 34 patients) is currently in remission (12 to 120 months). Treatment was primarily by chemotherapy and Chinese herbs, with adjunctive craniotomy in selected patients. Myelosuppression was the main side effect.

Adult↗
PubMed1983

Developmental changes of components of the red cell immune system in the rabbit.

Red cell immune adherence (RCIA) occurs not only in primates but also in nonprimates such as the rabbit. We utilized the rabbit as an animal model to study developmental changes in the immune functions of rabbit red cells. Significant differences between adult and newborn rabbits were found. RCIA-receptor activity of the newborn rabbits was significantly larger than that of adult rabbits (p less than 0.0005). Serum RCIA inhibiting factor, which completely prevented any detectable RCIA, was evident in about 40% of adult but not in any of the newborn rabbits (p less than 0.01). RCIA-inhibiting factor was also detectable in three out of eight pregnant rabbits but did not cross the placenta into the rabbit fetus. High concentrations (33%-100%) of most adult sera but not of newborn sera inhibited RCIA (p less than 0.001). It is suggested that, like the thymus, red cell immune function may reach its peak activity during early developmental periods. The red cell immune function may be essential for the removal of antigen-antibody complement complexes from the fetal circulation and may participate in the activation of T suppressor cells which adhere to autologous red cells.

Age Factors↗
PubMed1982

Immune complexes in pregnancy. III. Immune complexes in immune complex-associated conditions.

Seventeen patients during the third trimester of pregnancy with associated immune complex disease and/or immune complex state and their infants' cord blood were investigated for the presence of immune complexes. In comparing maternal levels of immune complex in normal third-trimester pregnancies to the study group, no statistical significant difference was noted. However, levels in cord blood were significantly lower (p less than 0.0025) than levels in paired maternal samples, but were found to correlate significantly (p less than 0.002). On the basis of the immunochemical analysis of selected pairs, the conclusion is that IgG-containing immune complexes may be responsible for this observed correlation and may represent the normal physiologic situation of pregnancy, whereas IgM-containing immune complexes may represent pathologic, and, therefore, abnormal, states. The suggestion is that the presence of such IgM-containing immune complexes may become predictive of fetoplacental compromise.

Antigen-Antibody Complex↗
PubMed1981

The red-cell immune system.

It is suggested that red cells have an immune function as well as a respiratory one. Adherence of red cells to antigen-antibody-complement complexes (red-cell immune adherence) has been observed in primates and in rabbits and may represent a basic immune phenomenon that is common to at least all mammals. It is estimated that 95% of C3b receptors in the human circulation are located on red cells and that an antigen-antibody-complement complex has a 500-1000 times greater chance of being removed from the circulation by a red cell than by a white cell. That red cells also adhere to autologous thymocytes and T cells suggests that they may act as intermediaries bringing antigens and T cells together.

Animals↗
PubMed1980

Insulinoma. Experience in surgical treatment.

Sixty cases of insulinoma were treated surgically. The possible causes for failure to find the tumor during exploratory surgery are discussed. Simple enucleation is preferred in most cases of single or a few insulinomas. A technique of enucleation with minimal chance of injury to adjacent pancreatic ducts and larger blood vessels can be used. When no tumor is found after thorough exploratory procedures, controlled staged resection of the pancreas under blood glucose monitoring is the procedure of choice. Postoperative complications are common but the late results are gratifying provided the operation is carried out early in the course of the disease.

Adenoma, Islet Cell↗
PubMedDate not supplied

Parenteral fat emulsions and immune adherence. The effects of triglycerides on red cell and neutrophil immune adherence in vitro and in vivo.

Parenteral fat emulsions may not only exert nutritional effects but may also affect immune adherence phenomena and red cell morphology. Red cell immune adherence (RCIA) was augmented in vitro by 0.05% to 0.1% Intralipid. Similar augmentation of RCIA was observed by peanut oil, corn oil, half-and-half cream, paraffin oil, and human low-density lipoprotein fractions. Neutrophil immune adherence was augmented in vitro by 0.2% to 1.5% of Intralipid. The effects of fat emulsions in vivo were studied in ten patients who received intralipid for nutritional purposes. Red cell immune adherence was augmented in five of ten patients and inhibited in four of ten patients. Neutrophil immune adherence was augmented in two of ten patients. Cytotoxic red cell transformations were evident in five of ten patients. Depression of RCIA in four of five patients was associated with cytotoxic red cell transformations.

Adult↗
PubMedDate not supplied

A quantitative study of the interphasic nucleolar organizer regions in two human cervical carcinoma cell lines.

We have studied the relationship between interphase nucleolar organizer regions (NORs) distribution and nucleolar size in cancer cells under prolonged culture. Six morphometric parameters (NUCLEAR SIZE, NOR NUMB, AREA SUM, MEAN AREA, SIZE RATIO and SIZE RATIO MEAN) of AgNORs in cancer cells were analyzed by an image analyzing system. The results show that the parameters NORN NUMB, AREA SUM and NUCLEAR SIZE demonstrate the most consistent changes in the two cervical carcinoma cell lines studied. These three parameters of AgNORs appear to be correlated with the degree of "dedifferentiation" that occurred in tumor cells under prolonged culture.

Cell Division↗