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Biomedical subjects

T L Hammond

Publications and source records attributed to T L Hammond.

8 recordsLinked to original sources

Amniotic cavity accumulation of magnesium with prolonged magnesium sulfate tocolysis.

In seven women, continuous intravenous tocolysis with magnesium sulfate for 4-28 days resulted in high amniotic fluid magnesium levels (10.54 mg% +/- 1.83 SD). In all cases the amniotic fluid magnesium level greatly exceeded the maternal serum level in a sample collected simultaneously. Additionally, when amniorrhexis and delivery occurred within one hour of each other, the fetal magnesium levels uniformly exceeded the maternal levels in paired maternal and cord blood samples.

Adult↗

Transverse lie.

To assess the impact of transverse lie on fetal and neonatal outcome, 14 mother and infant pairs with transverse lie were matched to 28 pairs with a vertex and 28 with a breech presentation. The control groups were matched for gestational age, route of delivery, type of anesthesia, and presence of labor. Infants in transverse lie were found to have a lower absolute arterial pH (7.21 versus 7.27, p less than 0.05) as well as more frequent severe acidosis (pH less than 7.1, 3 of 14 versus 0 of 56, p less than 0.04). Their birthweight was also less (2798 gm versus 3251 gm, p less than 0.05) and they sustained more birth trauma and long-term residual effects than either the breech (5 of 14 versus 1 of 28, p = 0.01) or vertex control groups (5 of 14 versus 2 of 28, p = 0.03). Based on these results, we recommend active intervention at 38 weeks' gestational age, via external version followed by labor induction, or failing this, cesarean delivery.

Adult↗

Guidelines for establishing a maternal serum alpha-fetoprotein screening program.

Maternal serum alpha-fetoprotein (MSAFP) screening of all pregnant women between 15 and 20 weeks gestational age is generally recognized as a standard of care in current obstetric practice. There are many factors to consider when deciding to establish MSAFP testing as an in-house procedure versus ship-out testing by a reference laboratory at fee-for-service cost. In this report, we review clinical and analytical aspects of MSAFP testing, along with appropriate guidelines for establishing an on-site MSAFP screening program.

Body Weight↗

Human papillomavirus associated with poor healing of episiotomy repairs.

A retrospective case-control investigation was conducted for risk factors in 47 parturients whose episiotomies dehisced in the immediate postpartum period. Data were extracted from the inpatient, outpatient, and pathology records of each of these 47 patients, as well as from the same records for each of the next two patients who delivered with the same type and degree of episiotomy. No difference between subjects and controls was found for age, parity, or medical history. Except for human papillomavirus (HPV), past or present history of sexually transmitted diseases was not a risk factor. However, active lesions, history thereof, or subsequent development of infection with HPV was found in 14 of 47 patients (29.8%) who had episiotomy breakdown, compared with 13 of 94 women (13.8%) who did not experience this complication, a statistically significant difference (P less than .023). Eleven subjects (23.4%) and nine controls (9.6%) gave a history of smoking during pregnancy, also a statistically significant difference (P less than .026).

Adult↗

Early repair of episiotomy dehiscence.

Early repair of episiotomy dehiscence was performed in 22 women with an initial fourth-degree episiotomy, four with third-degree episiotomy, and five with a mediolateral episiotomy. Early complications were limited to development of a pinpoint rectovaginal fistula in two women, both subsequently repaired by a rectal mucosal flap procedure. Of the 27 women now 1 year or more post-repair, all are completely continent and report resumption of normal coital activity.

Dyspareunia↗

Transvaginal-peritoneal migration of Trichomonas vaginalis as a cause of ascites. A report of two cases.

Genital tract colonization with Trichomonas vaginalis usually results in vaginitis without systemic manifestations. There are only four recorded cases of Trichomonas recovered from pelvic organs or peritoneal fluid. This report describes two additional women in whom motile flagellate organisms were recovered from abdominopelvic ascites. We hypothesize that an ascending trichomonal infection may have played an etiologic role in the development of their acute disease.

Animals↗

The use of automobile safety restraint systems during pregnancy.

The American Medical Association's Committee on Medical Aspects of Automobile Safety recommends that pregnant women use seat belts. Currently, all military installations, 39 states, and the District of Columbia mandate varying degrees of seat belt usage. A survey was conducted to evaluate seat belt usage in the antepartum population at the Wilford Hall United States Air Force Medical Center. Eighty-eight percent of the respondents used automobile safety restraints 100% of the time when driving, and 90% of the respondents used automobile safety restraints 100% of the time when riding as a passenger. Twenty-three percent, however, were uniformed or misinformed about seat belt safety procedures and practices during pregnancy. Increased education regarding seat belt safety would be beneficial to this population.

Accidents, Traffic↗