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Biomedical subjects

T Kumoi

Publications and source records attributed to T Kumoi.

51 records · Page 3Linked to original sources

Malignant histiocytosis in the oropharynx.

Malignant histiocytosis is characterized by systemic, progressive, and invasive proliferation of malignant histiocytes. The disorder is typically accompanied by fever, general fatigue, lymphadenopathy, and hepatosplenomegaly. A case of a 21-year-old woman with primary malignant histiocytosis of the oropharynx is reported. Histologic diagnosis from the biopsy specimen was confused by infiltration of normal-appearing histiocytes and inflammatory cells. The titers of Epstein-Barr virus and the Paul-Bunnell test were elevated without atypical lymphocytes. The patient died 3.5 months after the onset of symptoms. Autopsy revealed systemic neoplastic proliferation of malignant histiocytes. A review of literature on this subject revealed no cases of malignant histiocytosis primarily involving the oropharynx.

Adult↗

Malignant lymphoma presenting as a parotid mass.

Primary malignant lymphomas of the salivary glands are very rare. Three cases of diffuse B-cell malignant lymphomas, each developing as a parotid mass, were presented. The preoperative early diagnosis is essential in these cases to avoid an unnecessary radical procedure as well as to have a beneficial effect on the prognosis. If there were a possibility of malignant lymphoma, present authors stressed that an incisional biopsy should be performed for diagnosis. The usefulness of immunopathological diagnosis of these tumors has been discussed with regards to the prognosis.

Aged↗

Unusual case of metastatic carcinoma of eyelid.

A case of metastatic squamous cell carcinoma of the eyelid from the parotid gland in a 61-year-old woman is presented. Open biopsy of the cervical lymphadenopathy revealed the metastatic lesion of squamous cell carcinoma in the nodes. Histopathological examination of extirpated eyelid tumor also showed secondary squamous cell carcinoma probably from the squamous cell carcinoma in the parotid gland. Including this case presented here, 3 reported cases of the metastatic tumor from the parotid gland are mentioned and discussed.

Aged↗

The blood supply of the facial nerve in the human temporal bone.

The gross blood supply and intrinsic vascular anatomy of the facial nerve in the temporal bone are described, and their significance is discussed. At the vertical part of the facial nerve, the stylomastoid artery lies on its anteromedial side as far as the upper third of the nerve. The artery then loops around the lateral or medial side of the nerve, and divides into several branches. At the convex aspect of the genu, these branches anastomose with one another to form an arterial network, passing to the horizontal part. The petrosal branch of the middle meningeal artery reaches the geniculate ganglion and forms a profuse, fine arterial network. The main arterial trunk extends toward the second bend in the nerve, but it never reaches the vertical part. Studies on the draining veins are also described. Duplication of blood vessels from different sources was seen at the horizontal part of the nerve. This would suggest a special vulnerability of this area to vascular injury, since in our topographical study of Bell's palsy within two weeks of its onset, 72 out of 117 cases (61.5%) were found to have suprastapedial lesions.

Cadaver↗

Leiomyoblastoma of the larynx: report of a case.

Leiomyomas or benign tumors of smooth muscle origin are extremely rare in the larynx. A review of the literature revealed only 15 confirmed cases of leiomyoma, eight leiomyosarcomas, and no cases of leiomyoblastoma. An unusual case of "bizarre" laryngeal leiomyoma arising from the vocal cord, which is believed to be the first reported case in the literature is presented herein.

Humans↗

Cytochemical study of ouabain-sensitive, K(+)-dependent p-nitrophenylphosphatase activity in guinea pig facial nerve.

The localization of ouabain-sensitive, K(+)-dependent p-nitrophenylphosphatase (K-NPPase) activity, the second dephosphorylative property of the Na-K adenosine triphosphatase complex, was cytochemically studied in the intra-temporal portion of the facial nerve in normal guinea pigs using a cerium-based method. A fine-granular reaction product of the K-NPPase activity was observed on the cytoplasmic side of the axolemma of the axon cylinder, of the incisures of Schmidt-Lanterman, and of the nodes of Ranvier. No reaction product was detected on the periaxonal and outermost plasma membrane of Schwann cells and in the myelin sheath. In control tissue samples, the enzyme activity was almost completely inhibited by 10 mM ouabain, and no reaction was noted in medium without K+.

4-Nitrophenylphosphatase↗