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Biomedical subjects

T Kuberski

Publications and source records attributed to T Kuberski.

31 records · Page 2Linked to original sources
PubMed1979

Clinical manifestations of eosinophilic memingitis due to Angiostrongylus cantonensis.

Between 1959 and 1976, 34 patients were seen in Hawaii with eosinophilic meningitis. Angiostrongylus cantonensis was recovered from two of these patients. The remaining cases were presumed to be due to this parasite because of clinical and epidemiologic findings. The most likely source of infection for eight patients was ingesting raw terrestrial snails or slugs, and for six patients eating raw or poorly cooked crustaceans. Patients typically presented with severe headache; neck stiffness and fever were usually mild or absent. Paresthesias were noted by most adults. The cerebrospinal fluid (CSF) cell count ranged from 150 to 1500 leukocytes per cubic millimeter, with a mean eosinophil percentage of 38. CSF IgE levels were not abnormal in four patients so studied. Although two deaths occurred, the illness was typically self-limited, resolving completely with no specific treatment.

Adolescent↗
PubMed1979

Clinical observations on 3,009 cases of ciguatera (fish poisoning) in the South Pacific.

Clinical observations on ciguatera were collected between 1964 and 1977 on 3,009 patients from several South Pacific island groups. Patients generally presented with neurologic symptoms such as parasthesia, vertigo, and ataxia, in addition to gastrointestinal symptoms such as diarrhea, abdominal pain, nausea, and vomiting. Patients with this illness usually became symptomatic less than 24 hours after ingestion of the fish and most patients (76.8%) developed symptoms in less than 12 hours. Significant differences in certain symptoms were noted between Melanesian and Polynesian ethnic groups, suggesting a susceptibility difference, or a difference in the nature of the toxin found in different areas of the Pacific. Being poisoned multiple times appeared to result in a clinically more severe illness than disease observed in patients experiencing ciguatera for the first time.

Adolescent↗
PubMed1979

Eosinophils in the cerebrospinal fluid.

Eosinophils in the cerebrospinal fluid are an uncommon finding that is most often the result of a helminthic infection of the central nervous system. Information from the recorded literature suggests the differential diagnosis of this clinical observation is relatively limited. Therefore, in the appropriate clinical circumstances, cryptic cases of central nervous system disease might be resolved or the diagnostic possibilities at least narrowed by finding these cells in the cerebrospinal fluid.

Central Nervous System Diseases↗
PubMed1979

Status of granuloma inguinale in Papua New Guinea.

Granuloma inguinale has been endemic in Papua New Guinea for at least eighty years and recently appears to be increasing, particularly in the urban centres. Most patients were found to be recent migrants to the Port Moresby area with low socioeconomic status and poor personal hygiene. The disease was found more frequently in males. A possible association between carcinoma of the penis and granuloma inguinale was observed. Lesions were chronic, progressive and located mainly in the genital region. Attempts to culture the causative agent were unsuccessful.

Adolescent↗
PubMed1979

Cholera in the Gilbert Island. I. Epidemiological features.

An explosive epidemic of cholera due to Vibrio cholerae, biotype El Tor, serotype Inaba, was centered on the coral atoll of Tarawa, Gilbert Islands. This outbreak was a unique experience in the South and Central Pacific region. The principal mode of spread during the peak of the outbreak was probably through contamination of the main water supply. Tarawa lagoon water and shellfish were found to be contaminated with V. cholerae and ingestion of raw fish and shellfish from the lagoon also served as a source of transmission. This outbreak raises the concern of Rother outbreaks of cholera occuring on remote and poorly equipped Pacific islands where the environmental circumstances are conducive to cholera spread.

Antibodies, Bacterial↗
PubMed1977

Clinical and laboratory observations on patients with primary and secondary dengue type 1 infections with hemorrhagic manifestations in Fiji.

An extensive epidemic of dengue type 1 infection with a high incidence of hemorrhagic manifestations occurred on the island of Viti Levu, Fiji beginning early in 1975. Previous dengue outbreaks in this population were such that in 1975 two types of dengue patients were observed, one group of patients experienced primary dengue type 1 infection, whereas another experienced their dengue type 1 infection approximately 4 years after a dengue type 2 infection. Clinical and laboratory findings for the two forms of infection were assessed in patients hospitalized for their disease, usually with hemorrhage. With the exception of virologic and serologic findings, no important differences between these two groups were noted with respect to incidence and nature of hemorrhage and other clinical and laboratory findings. Both types of infection sometimes were associated with thrombocytopenia and low serum levels of the C3 component of complement. Virus was more easily isolated from the primary infection patients and the magnitude of their viremia also was higher. No significant differences were noted in a comparison of the ease of virus isolation from serum or plasma.

Adolescent↗
PubMedDate not supplied

Evaluation of the indirect hemagglutination technique for study of Trichomonas vaginalis infections, particularly in men.

The indirect hemagglutination (IHA) technique was evaluated for use in the serologic study of infection with Trichomonas vaginalis. The IHA test showed that sera from 88% of women attending a venereal disease clinic had antibody to T. vaginalis. The antibody frequency and titers were highest in women who had documented infections due to T. vaginalis. Serologic and cultural evidence of recent or active trichomonal infection was found in 11% of 85 men who had nongonococcal urethritis, but was absent in a control group of 27 men. Clinical findings in ten men with symptomatic genitourinary trichomoniasis are described; all but one had relatively high (greater than or equal to 1:80) IHA antibody titers. Antibody to T. vaginalis was found significantly (P less than 0.005) more often in sera from women than in sera from men in an apparently healthy group of individuals between the ages of 1 and 20 years. The IHA test appears potentially useful for the diagnosis of trichomoniasis in men and in the seroepidemiology of infections due to T. vaginalis.

Evaluation Studies as Topic↗
PubMedDate not supplied

Trichomonas vaginalis associated with nongonococcal urethritis and prostatitis.

Trichomonas vaginalis was recovered from three (1.7%) of 179 men with nongonococcal urethritis. Prostatitis was found in 11 (8%) of 138 of these men who had prostatic examinations; T. vaginalis was recovered from two of the 11. Serologic evidence (an indirect hemagglutination titer of greater than or equal to 1:80) was found in 20 (14%) of 146 men; four of the 20 had prostatitis and two of these had prostatitis associated with T. vaginalis. In a group of 26 men with urethritis and prostatitis associated with T. vaginalis, the typical clinical presentation was persistent urethritis and/or prostatitis due to an antibiotic-resistant agent.

Adult↗
PubMedDate not supplied

[Prevalence of diabetes mellitus and glucose tolerance abnormality in Melanesians and subjects of Polynesian descent in the rural areas of New Caledonia and at Ouvea (Loyalty Islands)].

The screening of different ethnic groups who live in the same natural system have enabled the authors to study interaction between genetic and environmental factors as a part of etiology of diabetes mellitus. In New Caledonian country areas, the prevalences of glucose tolerance abnormality (GTA) and diabetes mellitus (DM) have been higher with people of polynesian descent than with Melanesians. GTA 7.6 p. ct. versus 5.1 p. ct. DM 6.5 p. ct. versus 2.2 p. ct. The prevalence of these combined diseases have been 14 p. ct. with the Polynesians and 7.2 p. ct. with Melanesians. These two ethnic groups have shown mean ages and obesity rates similar enough to lead the authors to deny these two factors a major part in the difference between the ethnic prevalences of DM. Besides, the mean plasmatic glycemia two hours after a dose of glucose and the relative risk of DM and GTA according to age and obesity rate have shown that the slight differences between these groups are not involved in the different prevalences of DM. This inter-ethnic difference may be due to genetic factors. However, some environment linked factors besides obesity (such as diet and daily life activity) may share a major part in this difference.

Adult↗
PubMedDate not supplied

High frequency of HLA-B27 and Reiter's syndrome in Navajo Indians.

Eighteen cases of Reiter's syndrome were found in a population of approximately 6,000 Navajo Indians. The phenotype frequency of HLA-B27 in this population was found to be 36%. The area in which these people live is endemic for shigellosis, Shigella flexneri being the most common species isolated. Presumably the high frequency of HLA-B27 and shigella infections account for the high incidence and prevalence of Reiter's syndrome in this population.

Arizona↗