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Biomedical subjects

T Kogure

Publications and source records attributed to T Kogure.

At least 127 records · Page 7Linked to original sources

Superficial esophageal carcinoma. Radiological findings in double-contrast studies.

Most cases of superficial esophageal cancer have been reported in Japan and China. Radiological findings in 11 patients (13 lesions) are described. Superficial spreading cancer is difficult to detect despite widespread mucosal involvement. Double-contrast technique is essential, both to detect lesions and to demonstrate their extent. An irregular, rigid wall, mucosal abnormalities such as barium pooling and coating, and protrusions of various sizes and shapes are diagnostic features.

Aged↗

Radiographic features of gastric polyps in familial adenomatosis coli.

Recent reports have noted a high frequency of elevated mucosal lesions of the stomach in patients with familial adenomatosis coli. This paper describes an additional 10 cases from six different families. Nine patients had sessile polyps in various portions of the stomach. Six of these have been examined histologically; two were adenomatous and four hyperplastic. The need for meticulous examination of the stomach in patients with multiple colonic polyposis is emphasized.

Adenoma↗

Diffuse finely nodular lesions of the esophagus.

Double contrast study of the esophagus revealed a variety of diffuse finely nodular lesions, some of which have not been adequately reported. Acanthosis nigricans, superficial spreading esophageal cancer, leukoplakia, moniliasis, and esophagitis were found to produce this appearance. Typical cases of the first three diseases are demonstrated and the differential diagnosis discussed.

Acanthosis Nigricans↗

Enzymatic conversion of human group O red cells into Group B active cells by alpha-D-galactosyltransferases of sera and salivas from group B and its variant types.

Salivas from group B secretor or non-secretor, acting on O red cells in the presence of UDP-galactose, each converted them into B cells, which were agglutinated against anti-B human serum (1:512) at the titre of thirty-two-fold, while secretor or non-secretor group AB salivas converted O red cells into B active cells, which were agglutinated by anti-B human serum (1:512) at the titre of eight- to sixteen-fold. The results indicate that the alpha-galactosyltransferases which participate in the biosynthesis of group B substance are secreted in group B or AB salivas of both secretor and non-secretor types as well as in their sera. Agglutinabilities of enzymatically converted B-active red cells against anti-B human serum indicate that alpha-galactosyltransferase activities of both serum and saliva from a weak B (Bw) individual, who has weak B antigens in red cells and saliva, were lower than those of normal group B. The alpha-galactosyltransferase activities in group Bm sera were lower than those of normal group B, while the enzyme activities in salivas of group Bm were demonstrated to the same degree in normal group B salivas.

ABO Blood-Group System↗

Radiological manifestations of oesophageal involvement in acanthosis nigricans.

Radiologic features of two cases of acanthosis nigricans with oesophageal involvement are reported. The first case demonstrated diffuse, granular shadows throughout the oesophagus which were difficult to differentiate from oesophageal moniliasis. Another case showed many discrete and tiny elevations resembling pseudopolyposis of the colon. Emphasis is placed on radiological differential diagnosis from moniliasis and leukoplakia of the oesophagus.

Acanthosis Nigricans↗

The action of group Bm or CisAB sera on group O red cells in the presence of UDP-D-galactose.

Group B and AB sera, acting on O red cells in the presence of UDP-galactose, each converted them into B active cells, which were agglutinated by anti-B human serum (1:512) at the titer of 128-fold, while group Bm and A-1 Bm sera, converted O red cells similarly incubated into B active cells, which were agglutinated by anti-B human serum (1:512) at the titer of 8- to 16-fold. This indicates that alpha-galactosyltransferase activity in Bm and A-1 Bm sera may be about 1/8-1/16 that in B and AB sera. Group CisAB sera, even after absorption of cold anti-B agglutinins with packed, washed group B red cells, did not convert O red cells in the presence of UDP-galactose in such a way that they might agglutinate against anti-B human serum.

ABO Blood-Group System↗

Oxidative phosphorylation in mitochondria isolated from stressed rat heart.

Oxidative phosphorylation was measured polarographically in mitochondria isolated from rat heart. With regard to ADP/O ratio and respiratory control index, no differences were found among mitochondria isolated from normal, acutely (increased pneumatic resistance of the heart-lung preparation) and chronicly (renal hypertension) stressed heart. However, the acute stressed heart induced by strangulating the outflow tract of the heart-lung preparation showed clear depression and tendency to depression, respectively, in the level of ADP/O ratio and respiratory control index in mitochondria. The results indicate that there is no change in the oxidative phosphorylating mechanism of the myocardial mitochondria of nonfailed heart despite acute or chronic pressure loadings; however, there is an uncoupling of oxidative phosphorylation in mitochondria of the failed heart after acute strangulation of the outflow tract.

Adenosine Diphosphate↗