[Sanguinarine preparations to aid mechanical tooth cleansing].
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Biomedical subjects
Publications and source records attributed to T Kocher.
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This clinical study was an attempt to find out if a patient's home care plaque control at his or her abutment tooth is more effectively enhanced by a modified ridge lap or a hygienic pontic design. Oral hygiene was performed either with a tooth brush alone or in combination with an interdental brush. We found that the effectivity of interproximal toothcleaning was not influenced by the pontic design and that only interdental brushes permit a good plaque control at the proximal area of the abutment tooth. This implies that "self cleansing" is non-existent in these tooth areas.
A retrospective radiographical and clinical evaluation of 275 molars (59 patients) with different classes of furcation involvement was assessed. Flap operations with and without root resections had been performed and the patients were enrolled in a regular maintenance program for at least 4 years (up to 8 years). The life expectancy of molars with root resection was compared to molars conventionally treated by flap operation. Probing depth was reduced significantly on molars of the lower jaw even with class III involvement, progression of periodontal disease could be arrested. The progression of bone loss (mean 1.4 mm) in molars of the upper jaw with a class III involvement could be stopped only by root resection. During the observation period 12 teeth had to be extracted. 8 for nonperiodontal reasons. The long-term prognosis of class III furcations only treated by flap operation with or without tunnel preparations was as good as that of root resected molars.
In a retrospective study we assessed the acceptance of necessary modern periodontal treatment by more than 2200 patients in the years 1981-1987. 50% of the patients withdrew from treatment in the presurgical phase and 42% in the postsurgical maintenance phase; particularly during the first year the drop out rate was high (64%). One of the reasons could be a certain lack of health awareness and fading willingness of the patients for permanent cooperation as known from longstanding chronic diseases in general medicine. Therefore it remains necessary to enhance periodontal health awareness and to promote information on the cause and treatment of periodontitis and the subsequent maintenance care.
In a pilot study on psychological aspects of periodontal treatment more than 90% of 95 patients gave a positive rating of our approach of periodontal surgery by quadrants in cases of profound periodontitis. On the basis of their own experience with this course of surgery more than 90% of patients would recommend periodontal treatment to others. The results of our questionnaire survey confirm that their is no reason for doing periodontal surgery at one appointment. About half of the patient showed a reduction of their anxiety level in the course of surgical periodontal treatment. With increasing interval (1 year) a minor part of the patients partly modified their opinion on some of the questions asked.
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A clinical trial examined the effect of calculus removal on the enamel surface using a Gracey curette 5/6, an ultrasound unit, and three air scalers with five different tips, in terms of the rate of surface lesions and the extent and depth of the defects. A total of 140 teeth were copied to assess and measure the surface lesions. The hand-held instrument did not damage the tooth surface. For calculus removal with automatic instruments surface lesions were observed to be a function of the type of equipment and the tip configuration used, with sharp-edged instruments causing the more severe destruction. Therefore automatic calculus removal instruments should not be used for routine tooth cleaning. They should be reserved for first-time removal of old, hard, and very tough calculus.
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The activity of ketocyclazocine, a putative kappa opioid receptor agonist, was studied and compared with that of morphine, a mu opioid receptor agonist, and cyclazocine, a putative kappa and sigma opioid receptor agonist, vs. placebo in 10 drug abusers. The measures included vital signs and pupil measurements, established and new observer- and subject-completed psychopharmacologic questionnaires and several methods of drug discrimination. The results indicate that ketocyclazocine is different from morphine-like agonists in that it produces only minimal miosis and lacks euphoriant action. It causes a dysphoric state and was clearly discriminated from morphine. The dysphoria and pattern of responses was similar to cyclazocine though ketocyclazocine was discriminated from cyclazocine. This is consistent with the concept that morphine and ketocyclazocine have separate modes of primary activity. The similarity between ketocyclazocine and cyclazocine obscures the assignment of particular drug effects to activity at the kappa receptor.
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The aim of the present study was to evaluate the assessment of progression of demineralization by digital subtraction radiography. In each of 14 extracted human teeth, 2 approximal enamel demineralization lesions were induced in vitro to simulate dental caries. A modified tunnel preparation with glass ionomer fillings was performed on one lesion of every tooth as a model of caries inhibition. Every week, radiographs were obtained under standardized conditions over a period of 42 days. The radiographs were digitized and calibrated for grayscales. Reference landmarks were chosen and aligned for the different pictures by computer-assisted imaging to adjust the images for projective distortions. The images of the 7th, 14th, 21st, 28th, 35th and 42nd day were subtracted from the baseline radiograph. The mean value of gray values of the subtraction images was calculated and ANOVA tests for repeated measurements and paired t tests were used for statistical analysis. The results of the present study indicate that statistically significant gray level changes due to progression of demineralization could be detected in the radiographic images by subtraction analysis. Differences between glass ionomer-filled and nonfilled lesions failed to reach significance. The introduced method may have the potential to detect and document minute caries progression.