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Biomedical subjects

T Knoop

Publications and source records attributed to T Knoop.

7 recordsLinked to original sources
PubMed2000

Educational and psychosocial issues related to new treatment advances for metastatic breast cancer.

OBJECTIVES: To explore educational issues as well as psychosocial issues relating to finances, family, and hope that may arise with the introduction of new treatment strategies for metastatic breast cancer. DATA SOURCES: Review articles, textbooks, and personal communications. CONCLUSIONS: New treatment advances in metastatic breast cancer are multifaceted and complex. Nurses must provide a holistic approach to patients and are in an excellent position to guide patients towards treatment advances. IMPLICATIONS FOR NURSING PRACTICE: Patients look to nurses to provide answers and to serve as resources as new treatment advances develop.

Antibodies, Monoclonal↗
PubMed1999

Cardiac tamponade.

OBJECTIVES: To review the oncologic emergency of cardiac tamponade through a case study presentation/analysis and a discussion of the pathophysiology, diagnosis, treatment, and nursing management. DATA SOURCES: Research studies, review articles, book chapters, abstracts, and clinical practice. CONCLUSIONS: Cardiac tamponade is a potentially life-threatening condition that is not uncommon in the oncology setting. It can result directly from the malignant or metastatic process or from the treatment of the malignancy. Observation and prompt intervention are mandatory to deal effectively with cardiac tamponade. IMPLICATIONS FOR NURSING PRACTICE: Oncology nurses play important roles in identifying patients at risk for cardiac tamponade and in recognizing signs and symptoms of cardiac tamponade early so this life-threatening emergency can be treated promptly.

Carcinoma↗
PubMed1998

The macrophage-induced gene mig as a marker for clinical pathogenicity and in vitro virulence of Mycobacterium avium complex strains.

The capacity of 20 Mycobacterium avium complex isolates to multiply intracellularly in human monocyte-derived macrophages was assessed and correlated to the clinical relevance of each isolate and its reactivity with several candidate genetic virulence markers. The strongest correlation with a virulence phenotype was found for a conserved coding sequence of the macrophage-induced gene mig identified by a specific mig restriction fragment length polymorphism type.

Biomarkers↗
PubMed1996

Polycythemia vera.

OBJECTIVES: To review the proliferative nature of polycythemia vera (PV), clinical features, laboratory findings, treatment options and controversies, and nursing management. DATA SOURCES: Textbook chapters and review articles that pertain to polycythemia vera. CONCLUSIONS: Polycythemia vera is a chronic myeloproliferative disorder that can evolve into acute leukemia. Treatment options include phlebotomy, myelosuppressive agents, interferon, and platelet inhibitors. IMPLICATIONS FOR NURSING PRACTICE: Nursing management of the patient with PV is challenging because of the evolving nature of the disease and treatment-related complications. Close monitoring and compliance with the treatment plan is necessary.

Algorithms↗
PubMed1986

Sudden idiopathic hearing loss: psychopathology and antecedent stressful life-events.

Otologists repeatedly state that patients suffering from Sudden Idiopathic Hearing Loss (SIHL) often have significant emotional problems or stressful living conditions. The study described here compared males and females suffering from SIHL with controls without any impairment of the inner ear. Personality data were gathered by means of Faschingbauer's Abbreviated MMPI (FAM). Stress factors were assessed by an Inventory of Stressful Life-Events (ILE). SIHL patients reported more stressful life-events, whose distressing effects lasted until onset of symptoms, than controls. There was no significant influence of personality upon report of stress. Stress factors and inability to cope with these seem to be important psychological factors in SIHL patients, while psychopathological disturbances may be important for some but not for the majority of cases.

Female↗