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Biomedical subjects

T King

Publications and source records attributed to T King.

At least 109 records · Page 6Linked to original sources
PubMed1982

Islet changes induced by hyperglycemia in rats. Effect of insulin or chlorpropamide therapy.

To investigate the effect of hyperglycemia on normal islets, rats were made diabetic by a 95% partial pancreatectomy and treated with insulin, saline, or chlorpropamide for 3 mo. Histologic examination and morphometry of the residual pancreas showed islet enlargement and fibrosis that correlated with the mean lasting plasma glucose during the experimental period. Treatment of diabetes with insulin prevented the islet disorganization. The B-cell area per islet remained constant and was not affected by hyperglycemia. Chlorpropamide had little effect on the fasting plasma glucose or islet structure, and no "beta cytotrophic" effect was seen. Chronic hyperglycemia induces islet damage that may affect residual B-cell function in diabetes.

Animals↗
PubMed1980

An attempt to assess and predict adaptive behavior of institutionalized mentally retarded clients.

Institutionalized retarded clients (N = 142) were assessed on the Adaptive Behavior Scale (ABS) within 6 months of their admission to Woodhaven Center (Philadelphia) and approximately 12 to 18 months later. While clients were found to progress significantly on 7 of the 10 domains of Part One of the ABS, no significant gains were noted on Part Two. Selected client characteristics (age of admission, sex, IQ, AAMD etiological classification) were also examined as predictors of improvement on the ABS. None of these characteristics was significantly associated with gains on the ABS. The above findings were discussed in terms of specific characteristics of the client population and with respect to limitations of the ABS itself.

Adaptation, Psychological↗
PubMed1977

Implementation of laboratory screening procedures on a short-term psychiatric inpatient unit.

A health maintenance screening procedure was done on blood and urine specimens on 636 patients admitted to short term adult psychiatric ward. The data obtained was assessed by laboratory test and by its effect on the subsequent work-up and diagnostic thinking about those patients who had unexpected abnormal findings. The overall incidence of unexpected abnormal tests was low (3.0%). Similarly the incidence of new disease found by these procedures was low (between 2.2% and 8.5%). In no case was an underlying medical cause for the mental disorder for which the patient was admitted detected by the screening procedure. The authors conclude that these routine blood and urine screening tests add very little to the care of psychiatric inpatients.

Adult↗
PubMed1976

An automated microscope for cytologic research a preliminary evaluation.

A research-oriented system for automated microscopy is described from an operational point of view. The system consists of a microscope, a TV camera, an automatic cell finder and a servo-driven computer controlled stage. The system is interfaced to a NOVA 840 computer having 112,000 words of 16-bit core memory and extensive peripherals. It is capable of performing a wide variety of image processing tasks and is being used to study various aspects of automated microscopy, with applications in, but not limited to, cytology. Results of preliminary performance evaluations are given.

Autoanalysis↗
PubMed1974

Fetal brain growth: selective action by growth hormone.

Growth hormone was administered to pregnant rats maintained under dietary control, and fetal and placental growth and nutrition were examined. Growth hormone had a selective action on brain growth that could not be attributed to nutrient mobilization but suggested a trophic factor which is unique to the brain.

Animals↗
PubMedDate not supplied

Clinical management of premature rupture of membranes.

Premature rupture of membranes (PROM) is a common obstetric occurrence; yet, the management of a patient who presents with PROM is controversial. This article reviews the etiology of PROM, describes the evaluation of a patient who presents with PROM, and enumerates the pitfalls inherent in making the diagnosis. Research suggests that an expectant approach to PROM at term is preferable to immediate induction. The use of PGE2 gel is an option for women who have unfavorable cervices. Clinical management of preterm premature rupture of membranes (PPROM) is generally expectant, with controversies surrounding the use of amniocentesis, corticosteroids, and tocolytics. Each of these topics is reviewed and current research summarized.

Adrenal Cortex Hormones↗
PubMedDate not supplied

Certified nurse-midwife and physician collaborative practice. Piloting a survey on the Internet.

This pilot study was designed to describe the clinical areas of collaboration, financial structures, and sources of conflict for certified nurse-midwives (CNMs) involved in nurse-midwife and physician collaborative practice (CP). A questionnaire was posted on an electronic bulletin board maintained by the Community-Based Nurse Midwifery Education Program of the Frontier School of Nursing. The nonrandom, convenience sample consisted of 78 respondents. Their mean age was 42 years; they had been in practice for a mean of 10 years, and 56% had graduate degrees. Eighty-nine percent reported involvement in CP. Eighty-three percent co-managed higher-risk women, and 46% performed vacuum-assisted deliveries or were first assistants at cesarean sections. Forty-eight percent of CNMs did not bill in their own names, and only 12% had full hospital privileges. The most common sources of conflict in CPs were clinical practice issues (100% ever encountered), power inequities (92%), financial issues (66%), and gender relations (58%). Collaborative practice is a common form of practice for CNMs and suggests a model for collaboration in other sectors of the health care system. Future research should explore methods of reducing the potential for conflict between CNMs and physicians.

Adult↗