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Biomedical subjects

T Kawazoe

Publications and source records attributed to T Kawazoe.

At least 73 records · Page 4Linked to original sources

Application of mechanical mobility of periodontal tissues to tooth mobility examination.

Tooth mobility examination is important in planning dental treatment, as it may give an indication of alveolar bone loss and the condition of the periodontal ligament. In clinical dental diagnosis a manual tooth mobility examination is useful. However, its determination of tooth mobility is subjective and depends on the skill and experience of the clinician. The authors have previously reported on a device for measuring the biomechanical properties of human periodontium using an impedance head. Using this device, the mechanical mobility of periodontium can be measured and the mechanical parameters of the periodontal physical model are obtained. Tooth mobility is defined objectively on the basis of discriminant scores of mechanical parameters, and a mobility triangle (MT) figure is drawn as a record for visual interpretation. The paper describes the validation of the mechanical mobility measurements and their interpretation using mobility parameters and a personal computer to produce a mobility triangle figure. The method is compared favourably with clinical mobility measurement. The relationship of the model to underlying pathology is tested by measurements performed on various tooth model systems.

Biomechanical Phenomena↗

Non-invasive measurement of the deep temperature of the temporomandibular joint region.

This study was carried out to non-invasively measure the deep temperature of the temporomandibular joint (TMJ) region at rest and after 100 opening and closing movements of the mandible. Using a transcutaneous probe, we performed deep thermometry by the zero-heat-flow method. A RAM-Pack recording system was employed, and the data were processed by and stored in a microcomputer. In 20 normal male subjects, no differences were observed in the deep temperature of the right and left TMJ regions at rest and after exercise. However, in patients with temporomandibular disorders, the deep temperature of the symptomatic joint was higher than that of the asymptomatic joint. The difference, however, gradually decreased to normal with occlusal splint therapy. Thus, it is clear that the deep temperature of the TMJ region provides useful information about inflammation of the TMJ.

Adult↗

[Fundamental study on ceftriaxone].

Ceftriaxone (CTRX) was examined in the blood level and urinary excretion between a healthy group of 2 persons receiving 1 g CTRX for 1 day and the other of 3 patients with renal failure receiving 1 g for 3 days, both by intravenous injection or intravenous drip infusion. In the healthy group, the blood half-life time of CTRX was 6.0 hours in 1 person and 8.2 hours in the other, being 7.1 hours on average. The mean blood level in the healthy group was 199 micrograms/ml at peak and was 13 micrograms/ml at 24 hours after administration. In patients with renal failure, the peak blood level ranged from 136.8 to 161.1 micrograms/ml on the 1st day, from 163.1 to 217.0 micrograms/ml on the 2nd day and from 156.4 to 189.7 micrograms/ml on the 3rd day, showing no tendency of getting higher, while the bottom level did from 15.2 to 47.4 micrograms/ml on the 1st day, from 23.3 to 67.9 micrograms/ml on the 2nd day and from 10.9 to 72.6 micrograms/ml on the 3rd day. The urinary excretion rate was 54.6 +/- 3.7% on average in the healthy group while it ranged from 13.7 +/- 1.8 to 27.9 +/- 7.9% in the patient group. CTRX was effective especially against E. coli among the strains clinically isolated from the patients with renal failure. No side effects were observed in any case.

Adult↗

The effects of an incisal bite plane on rat sublingual glands.

Application of an incisal bite plane for as little as three d caused a significant increase in the size of the sublingual glands of rats, with some evidence of hyperplasia and hypertrophy of the acinar cells. The enlargement had few effects on salivary secretion, and the gland changes were reversible.

Animals↗

The effects of an incisal bite plane on rat submandibular glands.

The submandibular glands of rats subjected to application of an incisal bite plane became slightly, but not significantly, enlarged. However, in comparison with control animals, they secreted additional proteins identical with those secreted by glands enlarged by periodic incisor amputation or chronic isoproterenol treatment.

Animals↗