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Biomedical subjects

T Kawabata

Publications and source records attributed to T Kawabata.

At least 181 records · Page 10Linked to original sources
PubMed1977

Gas chromatographic determination of methylguanidine, guanidine and agmatine as their hexafluoroacetyletonates.

Seven derivatives of each of methylguanidine, guanidine and agmatine have been prepared, and the specificity and volatility of their gas chromatographic detection have been studied. The hexafluoroacetylacetonates have been found to be the most specific for the three guanidines, and are highly sensitive to alkali flame ionization and electron-capture detections. These derivatives are also fairly resistant to hydrolysis occurring in the derivatization process.

Agmatine↗
PubMed1977

HLA-BW35 and B5 in Japanese patients with Graves' disease.

Thirty-three Japanese patients with Graves' disease and 106 healthy controls living in the Kagoshima area, the southernmost part of the Japanese mainland, were HLA typed by the NIH method. None of them were related to each other. The only antigen showing an increased frequency in Japanese patients with Graves' disease was HLA-BW35 (corrected P less than 0.02). A decreased frequency of B5 in the patients was also statistically significant (corrected p less than 0.02).

Asian People↗
PubMed1976

Microbial formation of nitrosopyrrolidine from nitrosoproline.

The fate of orally administered NPro was determined in rats. Unchanged NPro could be recovered in the urine, while NPy was detected in the faeces of two of three rats tested. After successive administration of NPro to the same rats, their intestinal contents were inoculated into media containing NPro to test for NPy formation. Decarboxylation of NPro occurred in the faeces cultures from those rats whose faeces had contained NPy. When the faeces from 10 mice were inoculated into the NPro media, all gave negative reactions for NPro decarboxylation. However, when the faeces of eight rats and those of 15 rabbits were tested, two rats and one rabbit exhibited NPy formation. L-Pro and NPro decarboxylase reactions were tested on 24 strains of bacteria and three strains each of E. coli and Proteus mirabilis isolated from rat intestines. It was found that seven bacteria gave a positive reaction with L-pro decarboxylation, while only two species, both belonging to Pseudomonas, could decarboxylate NPro.

Animals↗