Direct ( pi +,pd) cross sections for light nuclei.
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Biomedical subjects
Publications and source records attributed to T Katsumi.
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A 49-year-old woman was admitted to our hospital with complaints of edema and abnormal shadow in right pulmonary area. CT scan and abdominal aortography showed left adrenal mass. Moreover, the lung metastasis measured 60 x 65 mm and bony metastases were suspected in three areas on bone scanning. Under diagnosis of left non-functioning adrenal tumor with pulmonary and bony metastases, left adrenalectomy was performed. Histological diagnosis was left adrenal cortical carcinoma without lymph node metastasis. Treatment consisted of 3 g o,p-DDD and 400 mg carmofur per day after surgery. At present, pulmonary metastasis has decreased in size and bony metastases decreased in uptake on bone scan 12 months postoperatively.
The clinical efficacy of enoxacin (ENX) was evaluated in 39 patients having chronic prostatitis. The overall clinical efficacy of ENX was determined by three factors, (1) the effect on bacteria, (2) white blood cells in the VB3 and (3) the subjective symptoms. The overall clinical effectiveness rate was 80%. ENX eliminated 66.7% of the bacteria in the VB3. As determined from white blood cells in the VB3, 56.4% of patients were relieved of the inflammation of prostate by ENX. The subjective symptoms were improved by ENX treatment in 77% of the patients.
Examination including residual urine measurement, cystometry and urethral pressure profile was performed before and 8 weeks, 3 months and 6 months after the operation in 17 patients with rectal cancer who were divided into mecobalamin administered group (8 patients) and non-administered group (9 patients) at random. Administration of mecobalamin (500 gamma i.m., 3 times a week for 4 weeks) was started within 3 weeks after the operation. In the 17 patients, the rate of patients with residual urine over 51 ml was 65% at 8 weeks, 24% at 3 months and 24% at 6 months. The mean value of bladder pressure at maximum capacity after the operation in the 17 patients showed a significant increase compared to that before the operation, while the mean value of maximum urethral pressure after the operation showed a significant decrease compared to that before the operation. The bladder pressure in patients with residual urine less than 50 ml was significantly lower than that in patients with residual urine over than 5 ml. The bladder pressure in patients with residual urine reduced to less than 50 ml at 3 months showed a tendency to decline. The rate of patients with residual urine of less than 50 ml at 8 weeks was 50% in the mecobalamin administered group and 22% in the non-administered group. There was no significant difference in bladder pressure between the two groups, or before and after the administration of mecobalamin.
A 59-year-old man was hospitalized with complaints of diarrhea and pollakisuria. Retrograde urethrography, urethroscopy and urethral pressure profile revealed a fistula between the urethra and the rectum situated immediately above the external urethral sphincter. Surgical repair was performed by an abdominal approach. Following the total prostatectomy, the fistula was completely resected under direct vision. A closure of the anterior rectal wall and an anastomosis between the urethra and the bladder neck was performed. Operative results were satisfactory. Operative methods for the urethrorectal fistula are discussed.
A 24-year-old female patient was was admitted because of urinary retention, four days after the development of rash with fever to be diagnosed as measles by a doctor. Neurological examinations showed hyperesthesia in lower thoracic regions and increased deep tendon reflexes in lower extremities. Cystometric findings revealed an areflexic bladder with normal sensation. Cerebrospinal fluid examination showed mononuclear pleocytosis and slightly elevated levels of protein. There was no significant increase in serum measles antibody titer. She regained normal voiding by conservative treatment with an indwelling catheter for four days. The bladder motor paralysis was probably due to non-transverse myelitis in sacral spinal region. Neurological complications of measles are briefly discussed.
Transurethral resection of the bladder neck was performed in 6 female patients with neurogenic bladders who presented with a large volume of residual urine and bladder neck obstruction on voiding cystourethrography without detrusor hyperreflexia on cystometry. In 4 of the patients, transurethral sphincterotomy was performed concomitantly. Five of the patients demonstrated significant improvement in bladder emptying and 4 did not need self-catheterization. No complications of the operation were observed.
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Urodynamic study was performed on 48 patients with benign prostatic hypertrophy. Twenty six of the patients had detrusor hyperreflexia. The mean age of the patients with detrusor hyperreflexia was higher, the mean value of urinary frequency was greater, the mean value of bladder capacity was smaller and the mean value of maximum voiding pressure was higher than those of patients without detrusor hyperreflexia. Small bladder capacity and high voiding pressure of patients with detrusor hyperreflexia were improved 3 months postoperatively. Eight of the 14 patients with detrusor hyperreflexia had normal bladder function, but detrusor hyperreflexia of the resting 6 patients was persisting. The mean value of posterior urethral length on the urethral pressure profile of patients with persisting detrusor hyperreflexia was shorter than that of patients with improved detrusor hyperreflexia. This suggested that the shorter length of posterior urethra may be a causative factor for persisting detrusor hyperreflexia.
An 81-year-old man with a painless enlargement of the right testis which developed 11 years ago was treated with right orchiectomy without any combined therapy in 1981. This tumor pathologically proved to be spermatocytic seminoma. The patient has been well and has shown no evidence of recurrence for the past 5 years.
A 56-year-old women was admitted for examination of glycosuria. She had had a blunt trauma onto the left abdomen 2 years ago that could have caused renal injury. Incidentally a left renal mass was detected by ultrasonography as a low echogenic mass. CT scan revealed a 2.5 X 2.5 cm mass with lower density than the kidney. IVP and renal angiography showed no abnormal findings. Under the diagnosis of renal tumor, left nephrectomy was performed. A 2 X 2 cm butter-yellow tumor, was seen in the renal parenchyma including the renal capsule of the upper and lateral part of the kidney. The renal pelvis was normal and there were no suppurative lesions in the kidney. Histopathological diagnosis was xanthogranuloma of the kidney partly containing a subcapsular hematoma. The previous blunt trauma, presence of hematoma and no evidence of suppurative lesions suggested that the etiology of xanthogranuloma in this case was related to renal injury.
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Urodynamic investigations and the measurement of the R-R interval on ECG have been applied to assess the extent of autonomic and peripheral neuropathy in 12 patients with diabetes mellitus. Objective evidence of neuropathic bladder dysfunction was detected in 6 patients (50%) and these cases were included under 2% of the coefficient of R-R interval variation. The commonest abnormality was hypotonic, large bladder and marked residual urine, which was usually asymptomatic. It is concluded that in diabetic patients this simple autonomic function test is a good guide to vesical function.
We reviewed 41 patients who were evaluated for the urethral syndrome. Evaluation included urinalysis, cystoscopy and the measurement of the R-R interval on ECG in all cases. The coefficient variation of R-R interval in urethral syndrome was significantly lower (p less than 0.001) than that of the healthy individuals. Treatment by mecobalamin showed that 4 of the 6 patients benefitted considerably.
Two cases of parathyroid cyst were experienced. Both cases presented clinical data and symptoms of hyperparathyroidism. Microscopically, one had a thin fibrous wall containing parathyroid adenomatous tissue in the inner surface and the other showed cyst formation without any histological evidence of adenoma or hyperplasia. Most parathyroid cysts are non-functioning. In occasional cases, the cyst may contain a hyperfunctioning adenoma. The hyperfunctioning parathyroid cysts with normal parathyroid tissue are discussed.
The clinical effectiveness, safety and usefullness of the alpha-adrenergic blocker, Ea-0643 tablet, for the treatment of the neurogenic bladder were evaluated by the double blind test method. A total of 61 patients was treated. Five of them were excluded or dropped out. Eighteen patients (group-A) received a 1.0 mg tablet of Ea-0643, 20 patients (group-B) received a 0.5 mg tablet of Ea-0643 and 17 patients (group-C) received a placebo tablet. Each tablet was administered orally three times a day for two weeks. There was no significant difference in the background factors between the three groups. The rate of effectiveness for subjective symptoms was 22.2% in group-A, 30.0% in group-B and 35.3% in group-C. There was no significant difference between the three groups. The rate of effectiveness for residual urine, judged by decrease in value of residual urine rate after treatment of less than 25%, was 55.6% in group-A, 35.0% in group-B and 17.6% in group-C. The rate of effectiveness in group-A was significantly higher than that in group-C. The mean value of net decreased residual urine rate after treatment in group-A was significantly higher than that in group-C. Decrease of maximal urethral pressure by more than 5 cm H2O was seen in 44.4% of group-A, 35.0% of group-B and 41.2% of group-C. There was no significant difference between the three groups. The rate of improvement for flow rate was 66.7% in group-A, 46.2% in group-B and 36.4% in group-C.(ABSTRACT TRUNCATED AT 250 WORDS)