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Biomedical subjects

T Kasugai

Publications and source records attributed to T Kasugai.

150 records · Page 9Linked to original sources
PubMedDate not supplied

Brushing cytology for the diagnosis of gastric cancer involving the cardia or the lower esophagus.

In 173 patients with gastric cancer involving the cardia or the lower esophagus, endoscopic biopsy and/or brushing cytology were utilized in establishing the diagnosis microscopically. Biopsy was positive in 132 of 170 patients (77.0%) while brushing was positive in 78 of 93 patients (83.8%). However, a combined use of biopsy and brushing yielded a higher diagnostic accuracy of 88.0 per cent. Further, endoscopic findings of the lower esophagus or the cardial orifice and diagnostic yields of the two methods were correlated. In patients with mucosal elevation, thick fold or a tight cardial stenosis as a pattern of esophageal involvement by gastric cancer on esophagoscopy, supplementary application of brushing increased diagnostic accuracy approximately 20 per cent compared to that of biopsy alone. It is concluded that brushing cytology should be utilized more frequently in gastric cancer involving the cardia to the lower esophagus, especially in the three types of esophageal involvement mentioned above.

Biopsy↗
PubMedDate not supplied

Endoscopic cytology of the esophagus, stomach and pancreas.

Cytology and biopsy under direct vision using a fiberscope as microscopic diagnostic procedures for carcinoma of the esophagus and stomach were described, and results of cytology were evaluated as compared with the results of biopsy. The diagnostic accuracy of brushing cytology under direct vision using a fiberscope was 97% in 116 cases of esophageal carcinoma and 78% both in 119 patients with carcinoma of the gastric cardia and in 63 patients with gastric carcinoma exclusive of the cardia. The diagnostic accuracy for cytology of pancreatic juice collected by cannulation in 36 patients with carcinoma of the pancreas was 56%: 79% for carcinoma of the head of the pancreas, but only 35% for carcinoma of the body and/or tail. For the esophagus and stomach, the diagnostic accuracy of direct vision biopsy has become almost as high as with cytology. As such biopsies are easily performed, esophagogastric cytology has become in our clinics a supplementary routine to the biopsy, and is done in a limited number of cases in which the biopsy failed or was not appropriate. However, cytology of the pancreas, in which biopsy is difficult, is important as the only microscopic diagnostic procedure. There, the development of newer instruments and the improvement of techniques of cell collecting are required, as is the development of expertise in the interpretation of cells from pancreatic carcinoma, in which the diagnostic accuracy is still relatively low.

Biopsy↗
PubMedDate not supplied

The diagnosis of pancreatic cancer by pancreatic juice cytology.

Cytologic examination of pancreatic juice collected during cannulation was performed on 105 patients. Positive results were obtained in 23 of 44 cases (52.3%) of carcinoma of the pancreas. Cytologic specimens were collected by direct suction, washing with saline, aspiration after secretin stimulation and brushing. Washing with saline (63.2%) and aspiration after secretin stimulation (51.3%) gave higher positive results than did the other two methods. Positive results when obtained in carcinoma of the head in 12 of 17 cases (70.6%) and in carcinoma of the body and tail in 9 of 24 cases (37.5%). The results were better in carcinoma of the head, and it is necessary to further improve the method of collection in carcinoma of the body and tail.

Cholangiopancreatography, Endoscopic Retrograde↗