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Biomedical subjects

T Kanazawa

Publications and source records attributed to T Kanazawa.

At least 253 records · Page 14Linked to original sources
PubMed1981

Experimental study on lymphatic vascular changes in the development of cancer.

Sudan Black B and Sudan Blue can partly enter the lymphatics of the small intestine from the lumen with long chain fatty acids. By use of a fat emulsion saturated with them small intestinal and mesenteric lymphatics were clearly delineated. Subserosal and mesenteric lymphatics of the small intestine appeared as blue lines. With this method we studied anatomical changes of the lymphatic vessels during the development of cancer. As experimental tumor VX2 carcinoma was used. Lymphatic vessels were not be found in cancerous regions by this lymphangiographic procedure, even in the early stages of cancer. Lymphatics passing through the tumorous tissue were completely obstructed and accompanied with peripheral dilatation. Compared to the morphological changes of the blood vessels, which were studied microangiographically, the lymphatic vessels were more easily affected by the malignant growth.

Animals↗
PubMed1980

Evidence that cell bodies of non-cholinergic, excitatory neurones which supply the smooth muscle of the chicken rectum are located in the ganglia of Remak's nerve.

1. A pharmacological investigation of the distribution of non-cholinergic excitatory nerve cell bodies was performed on the chicken's isolated perfused rectum with attached Remak's nerve supply. 2. Electrical stimulation of Remak's nerve trunk produced a contraction and a discharge of action potentials in the nerve branches which supply the smooth muscle of the rectum. Both responses were virtually blocked by hexamethonium when applied via the caudal mesenteric artery. 3. The contractile effect following stimulation of the nerve trunk was inhibited more effectively by hexamethonium when application was restricted to the trunk rather than to the intestine. 4. The contractile effect of stimulating the nerve branches was unaffected by hexamethonium. 5. It is concluded that ganglionic transmission, which is mediated by nicotinic receptors, occurs in the ganglia of Remak's nerve but not in ganglia of the enteric plexuses. Therefore, cell bodies of the postganglionic neurones which are considered to be non-cholinergic are located in Remak's nerve ganglia.

Action Potentials↗