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Biomedical subjects

T Kalman

Publications and source records attributed to T Kalman.

3 recordsLinked to original sources

Fluphenazine resistant psychosis.

A fifty year old female chronic schizophrenic was admitted to hospital following a relapse of her psychosis. She had previously responded well to treatment with trifluoperazine but because of her history of medication non-compliance, a trial of fluphenazine enanthate was instituted. Despite the close chemical similarity between trifluoperazine and fluphenazine the patient failed to respond to the latter in either its oral or depot intramuscular form. Although it is not unusual for a patient to respond to one antipsychotic and not to another, the above case of intra-class non-responsiveness is indeed rare and not readily explained. We present this unusual case and discuss some possible explanations.

Chronic Disease↗

Protracted vomiting following abrupt cessation of psychotropics: a case report.

The case of a 23-year-old patient treated with haloperidol, imipramine, and benztropine mesylate is presented to illustrate an unusually severe reaction to the abrupt cessation of neuroleptic medication. In addition to the description of the withdrawal reaction, a possible explanation of the clinical phenomenon is offered.

Adult↗