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Biomedical subjects

T K King

Publications and source records attributed to T K King.

At least 37 records · Page 2Linked to original sources

Pulmonary function in asymptomatic adolescents with idiopathic scoliosis.

Pulmonary function studies were performed in 28 asymptomatic adolescents with idiopathic scoliosis. Tests included spirometry, flow volume curve, measurements of inspired gas distribution, diffusing capacity, closing volume, ventilatory response to carbon dioxide, and arterial blood gas analysis. In addition to the well-known decreases in lung volumes, a reduction in diffusing capacity, arterial oxygen tension, and ventilatory response to carbon dioxide were also documented. Significant correlations existed between the severity of the spinal curvature and the decrease in lung volumes. A significant correlation was also found between the degree of hypoxemia and the reduction in the diffusing capacity, suggesting that a low diffusing could be the cause of the observed arterial hypoxemia.

Adolescent↗

Miliary tuberculosis presenting as acute respiratory failure: treatment by membrane oxygenator and ventricle pump.

A 58-year-old woman with high fever, dyspnea, rapidly progressive hypoxemia and opacification of the lung fields presented the clinical picture of catastrophic respiratory failure. Extracorporeal support of oxygenation using a membrane oxygenator and a new ventricle pump was initially successful. At autopsy, miliary tuberculosis was found to be the cause of this "shock lung like" syndrome.

Assisted Circulation↗

Diffusing capacities and ventilation: perfusion ratios in patients with the clinical syndrome of alveolar capillary block.

Studies were performed on 10 patients with the clinical syndrome of alveolar capillary block while each patient was breathing four different inspired oxygen mixtures. The data were interpreted using the principle of the Bohr integral isopleth with which alveolar oxygen tension in the differently ventilated parts of the lung can initially be treated as unknown. It is then possible to determine the distribution of ventilation, of perfusion, of diffusing capacity, of lung volume, and of alveolar and end capillary blood oxygen tension in the variously functioning parts of the lung. In two patients shunts were the major factor interfering with oxygen transfer. In four others inequalities in ventilation: perfusion ratios and in diffusing capacity in different parts of the lung were the factors interfering with oxygen transfer. In four more patients ventilation: perfusion ratios were the same throughout the lung, the only disturbance of oxygen transfer being in the total diffusing capacity or in its distribution between the different parts of the lung.

Adult↗