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Biomedical subjects

T Jones

Publications and source records attributed to T Jones.

583 records · Page 33Linked to original sources

Burn contractures: incidence, predisposing factors, and results of surgical therapy.

An important element in the care of the burn victim is the prevention and treatment of burn wound contractures. Since limited objective quantitative information is available on the incidence of contractures after thermal injury, or on the factors that predispose individuals to their development, a review of all patients seen from July 1980 through January 1986 for surgical correction of burn wound contractures was conducted. Among the 53 patients selected for study, the incidence of contractures was higher in the pediatric patients, 7.8%, than in the adult patients, 2.0% (P less than 0.001), although burn wound size was comparable in these two groups. There was a direct relationship between wound size and number of contractures per patient (P = 0.003). The majority of contractures occurred at the hand, head, neck, and axilla. Surgical release of contractures of these central body regions (P = 0.056) and of fascially excised burns (P = 0.04), yielded the poorest operative results. Patient age and race, type of operation performed, and timing of surgery did not affect the operative results.

Adolescent↗

Sonographic appearance of callosal agenesis: correlation with radiologic and pathologic findings.

Sonographic features are described in six infants in whom total or partial agenesis of the corpus callosum was confirmed by either computed tomographic or pathologic examination. The six patients demonstrated a range of abnormalities involving the neuraxis as well as other systems, notably cardiovascular, gastrointestinal, and genitourinary. Chromosomal abnormalities were present in two patients. The sonographic features of callosal agenesis seen in these patients included: lack of characteristic acoustic interfaces to define the corpus callosum on both coronal and sagittal sonograms; increased separation and parallelism of the bodies of the lateral ventricles; loss of the characteristic convexity of the medial border of the anterior horns of the lateral ventricles; variable prominence of the occipital horns of the lateral ventricles; variable degree of superior extension of the third ventricle; alteration or absence of the cavum septi pellucidi; and radial arrangement of cerebral sulci about the prominent third ventricle. Cases of partial agenesis may show the dysplastic features found in complete agenesis. However, only some of the callosal echoes are present. The sonographic features of partial agenesis in one infant had not been described before.

Agenesis of Corpus Callosum↗

An inner-city cancer prevention clinic in West Oakland, California.

This article reports on a 3-year (1989-1992) American Cancer Society demonstration project in which a multidisciplinary, continuity-of-care-based comprehensive cancer prevention, education, and early detection clinic was established within an already existing inner-city health center in West Oakland, California. A total of 2058 patients (79% African-American, 78% female, 50% medically uninsured) received 7349 services (3.6 services per patient; averaging 2.5 hours over multiple visits, with 75%-85% appointment-keeping compliance), ranging from risk assessment and education to physical examinations, smoking counseling, mammography, and flexible sigmoidoscopy. In addition to 22 precancers and 15 cancers being diagnosed, statistically significant gains were demonstrated in patient knowledge, attitudes, and behavior. There was high patient satisfaction, particularly with nurse practitioners as service providers. Cancer prevention education was provided to an additional 14,945 community members, targeting students, teen parents, and recovering substance abusers. An in-depth qualitative analysis of recovering substance abusers examined their cancer beliefs and attitudes and showed significant knowledge gains from a subsequent cancer education program. The overall project demonstrated the feasibility of providing comprehensive and effective cancer prevention, education, and early detection services to the poor.

Adolescent↗

Competition between nonplaquing and plaquing strains of Newcastle disease virus as affected by temperature.

If lentogenic (nonplaquing) strains of Newcastle disease virus were inoculated into a monolayer of chicken embryo fibroblasts before velogenic (plaquing) strains, the plaquing of the latter were inhibited partially or completely. An interval of 22 hours between the two inoculations gave greater inhibition than did 1 hour. In general, lentogenic strains grew better at 37 C (inhibited plaquing more effectively) than at 42 C. Enzootic velogenic strains that produce a neurotropic form of the disease in chickens were inhibited more than were exotic velogenic strains that produce a viscerotropic form. The lentogenic strains differed markedly in ability to interfere with velogenic strains.

Animals↗