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T J Kline

Publications and source records attributed to T J Kline.

12 recordsLinked to original sources

Path model analyzed with ordinary least squares multiple regression versus LISREL.

The data of a specified path model using the variables of voice, perceived organizational support, being heard, and procedural justice were subjected to the two separate structural equation modeling analytic techniques--that of ordinary least squares regression and LISREL. A comparison of the results and differences between the analyses is discussed, with the LISREL approach being stronger from both theoretical and statistical perspectives.

Data Interpretation, Statistical↗

Common method variance and specification errors: a practical approach to detection.

The purpose of this study was to demonstrate how examining the bivariate correlations between items in self-report measures can assist in differentiating between possible common method variance vs. model specification errors. Specifically, social desirability was viewed as either a possible source of common method variance or as a theoretically meaningful construct that should be included in the model of interest (i.e., a specification error). In the first instance, LISREL was used, and the level of correlation between measures of social desirability and measures of the five constructs of interest was manipulated. These results provided some insight as to when one needs to be concerned about the possible "common variance effects" on the structural model. In the second instance, the correlations between measures of social desirability and the measures of only two constructs of interest were again manipulated. These analyses illustrated the point at which the omission of social desirability as a theoretically relevant variable began to result in a poor fit of the structural model.

Adult↗

Liability issues with the Papanicolaou smear: general legal background.

All diagnosticians are aware of malpractice and its implications. To allay justifiable fears, familiarity with legal terminology and legal procedures is invaluable. In this article, the ramifications of malpractice coverage, the tenets of risk management, and the proceedings related to a malpractice lawsuit are clarified. Factors that can decrease the possibility of a lawsuit are clear communication, precise documentation, and attention to the multiple details that are intrinsic for every laboratory.

Female↗

Squamous metaplasia of extrahepatic biliary system in an AIDS patient with cryptosporidia and cholangitis.

AIDS-related cholangiopathy is an increasingly recognized syndrome associated with significant morbidity and mortality. The mechanism of cholangiopathy is unknown but is assumed to be related to infectious pathogens such as CMV and cryptosporidia. The case of a Haitian with HIV and long-standing intestinal cryptosporidiosis who presented with cholangitis and protuberant intrabiliary filling defects is reported. Histopathological examination of biliary biopsies revealed previously unreported extensive squamous metaplasia of the bile duct epithelium, and the histogenesis of this condition is discussed. Chronic cryptosporidial infestation may be directly pathogenic resulting in squamous metaplasia that mimics biliary malignancy.

AIDS-Related Opportunistic Infections↗

Vision, aging, and driving: the problems of older drivers.

Although there are well-recognized declines in visual functioning with age, their contribution to the problems of older persons on tasks in the natural environment, including driving, are largely unknown. Adults ranging in age from 22-92 years were surveyed in regard to their visual difficulties when driving and performing everyday tasks. The visual problems of drivers increased with age along five different visual dimensions: unexpected vehicles, vehicle speed, dim displays, windshield problems, and sign reading. Several of the age-related visual problems that were reported appear to be related to the types of automobile accidents more common among older drivers. The study also replicated the findings from an earlier investigation of non-driving tasks that showed visual declines with age on five dimensions: visual processing speed, light sensitivity, dynamic vision, near vision and visual search. These findings indicate promising areas of research regarding the effects of visual aging on tasks in the natural environment.

Adult↗

Radiologists, communication, and Resolution 5: a medicolegal issue.

Resolution 5, adopted by the American College of Radiology, sets forth principles of direct communication that are important to every radiologist. This article reviews pertinent court decisions that affect radiologists and illustrates the importance of Resolution 5. In recent cases in state courts, liability standards have focused on four areas: negligence based on failure to personally inform clinicians of the diagnosis, ability of the jury to decide whether the radiologist's actions were appropriate, provision of information to the correct person, and necessity for expert testimony to define urgency. An important factor in liability cases appears to be the judgment of the radiologist in selection of the correct individual to receive the radiology report. The authors believe that electronic communication devices (eg, voice mail and fax machines) may potentially breach confidentiality and that such devices should therefore be used sparingly. Verbal communication by the radiologist to the referring physician, in addition to a written report, should avoid liability and improve quality of care for the patient.

Communication↗

Biphasic effect of duodenal ulcerogens on gastric emptying in the rat.

The effect of the duodenal ulcerogen cysteamine on gastric emptying of a liquid meal was compared to that of two newly identified duodenal ulcerogens, MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and mepirizole. Emptying rates after acute and chronic treatment with duodenal ulcerogens were obtained. Acute administration of cysteamine, MPTP, or mepirizole significantly delayed gastric emptying of the meal. Chronically treated rats, however, showed either no change or accelerated gastric emptying after cysteamine, MPTP, or mepirizole. Gastric emptying in chronically treated animals was faster in rats that developed the most severe duodenal ulcers. These results indicate that delayed gastric emptying instead of accelerated emptying is a more common abnormality during duodenal ulceration. After the ulcer develops, however, unaltered or accelerated gastric emptying is observed experimentally, thus suggesting that accelerated gastric emptying in duodenal ulcers is an acquired alteration. The implications that these experimental findings may have in the pathogenesis of duodenal ulcer, in light of the clinical data available, are discussed.

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine↗

Duodenal ulcerogens cysteamine and propionitrile induce gastroduodenal motility alterations in the rat.

The effects of the duodenal ulcerogens cysteamine and propionitrile on gastroduodenal myoelectric activity and intraluminal pressure in the fasted rat as well as on contractility of isolated gut muscle strips were investigated. Duodenal ulcerogens, unlike the nonulcerogen but toxic analogue ethanolamine, caused an early disruption of the myoelectric migrating complex, a marked increase in the spiking activity, and a decrease in the frequency of the slow waves in the duodenum. Both the increased spiking activity and the decreased slow wave frequency were dose dependent for cysteamine. Manometrically recorded contractions at the stomach corpus, midantrum, and antropyloric region as well as in the proximal duodenum of the conscious rat showed decreased contractions at the corpus and midantrum and an increase at the pyloric and duodenal sites during an intravenous infusion of cysteamine. In vitro studies demonstrated that circularly or longitudinally cut muscle strips taken from different regions of the stomach and duodenum responded to cysteamine with increased contractility. In summary, the duodenal ulcerogens cysteamine and propionitrile rapidly induce motor abnormalities in the stomach and duodenum of the rat. In vitro studies suggest that a cholinergic mechanism may be involved. It is possible that motor changes play a role in the pathogenesis of the experimentally induced duodenal ulcers.

Acetylcholine↗