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Biomedical subjects

T J Coady

Publications and source records attributed to T J Coady.

12 recordsLinked to original sources
PubMed1976

Determination of the optimum dose of subcutaneous salbutamol in asthmatic patients.

Saline and salbutamol (250 mug, 500 mug, 750 mug, and 1000 mug) injections were administered under double-blind conditions to seven chronic stable asthmatic patients. The response on the respiratory system (FEV1, FVC) and cardiovascular system (pulse rate, blood pressure and ECG) was monitored for 3 hours. Increasing the dose of salbutamol increased the peak and weighted average effects of FEV1 and pulse rate. The optimum dose, a titration of desired increases in FEV1 and undesirable increases in pulse rate, is 500 mug but doses up to 1000 mug may be administered if necessary.

Adult↗
PubMed1976

Evaluation of a breath actuated pressurized aerosol.

Preliminary investigation suggests that some asthmatic patients find it difficult to synchronize the release of a metered dose from a pressurized aerosol with the correct phase of inspiration. An automatic device has been developed to overcome this problem. Information is presented outlining the physical characteristics of the unit and the methods used to establish its performance in patients. It is suggested that the device may have a place in the management of asthma.

Aerosols↗