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Biomedical subjects

T J Clark

Publications and source records attributed to T J Clark.

At least 145 records · Page 8Linked to original sources
PubMed1972

Effect of mechanical loading on ventilatory response to CO2 and CO2 excretion.

The ventilatory response to CO(2) (S) and respiratory exchange ratio have been measured in 10 healthy subjects breathing naturally and through added resistive loads. The changes in these values produced by the added loads were shown to be correlated with the unloaded CO(2) responsiveness. The results indicated that poorly responsive individuals had a greater depression of ventilatory response to CO(2) and were more liable to retain CO(2).These observations raise the possibility that the constitutional CO(2) responsiveness of an individual influences the alveolar ventilation achieved in the presence of airways obstruction. The propensity to develop respiratory failure may thus be conditioned by the premorbid CO(2) responsiveness.

Adult↗
PubMed1971

Exchange transfusion with dextran 40 in polycythaemia secondary to hypoxic lung disease.

In eight patients with polycythaemia secondary to hypoxic lung disease 10 elective exchange transfusions were performed to reduce red cell mass, packed cell volume (P.C.V.), and whole blood viscosity. The rationale for reducing P.C.V. is discussed. It is concluded that patients with P.C.V. of 60% or over will benefit from exchange transfusion and that most patients with P.C.V. over 50% and true polycythaemia will also benefit. We also confirm that the technique of exchange transfusion is a rapid, safe, and effective method of achieving large venesections and reducing red cell mass.

Aged↗
PubMed1971

Reliability of patient monitoring apparatus.

Assessment of a patient monitoring system used in a general medical intensive care ward showed that the blood pressure subsystem was unreliable. The method used in this study is discussed in relation to the clinical requirements of patient monitoring apparatus.

Blood Pressure Determination↗