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Biomedical subjects

T Iwase

Publications and source records attributed to T Iwase.

At least 217 records · Page 12Linked to original sources
PubMed1981

[The computerized display of epicardial mapping (author's transl)].

UNLABELLED: The epicardial mapping is necessary for the surgical treatment of drug-resistant cardiac arrhythmia. The procedure for the epicardial mapping consists of three stages: 1) recording of heart potentials, 2) extraction of excitation transmission time, and 3) display of epicardial mapping. In this paper, our new microcomputer-based system was discussed. It was achieved by this system to simplify the method for the extraction and to make the colorgraphic display of epicardial mapping. Two methods for extraction were used in this study to compare with manual operation: 1) D method; extracting the time, when the differentiated wave takes maximal potential, and 2) Wi method; extracting the time of (Formula: see text). RESULTS: 1) similar epicardial excitation maps were obtained by these computerized methods, and 2) the most approximate values of the transmission time was obtained by Wi (i=2) method.

Computers↗
PubMed1980

Localization and interruption of accessory conduction pathway in the Wolff-Parkinson-White syndrome.

We operated upon 36 patients with Wolff-Parkinson-White (WPW) syndrome between 1969 and July, 1979. The relationship between the electrocardiogram (ECG), particularly the delta wave, and localization of the accessory conduction pathway (ACP) was analyzed, and the value of preoperative examinations such as vectorcardiography, echocardiography, body surface mapping, intracavitary potential study, and cardiac pacing were demonstrated. Epicardial mapping was indispensable as an intraoperative study and represented the most effective method for localizing the ACP. In some cases, endocarial potential study was found to be efficacious. Detachment of the atrium from the ventricle by an incision along the anulus at the area of earliest pre-excitation, resulted in complete correction in 26 of 28 patients operated upon between 1973 and July, 1979. In five patients multiple ACPs was corrected, although four of them required a second operation. The surgical indications in the WPW syndrome should be expanded in view of the high success rate and the safety of the operation.

Adolescent↗
PubMedDate not supplied

Comparison of non-tryptophan fluorophores in protein-free extract of brunescent and non-brunescent human cataract.

PURPOSE: To investigate whether any of the fluorophores in the human lens nuclei might be responsible for human brunescent cataract formation. METHODS: Human lens nuclei (non-brunescent, from 13; brunescent, from 8) were obtained after extracapsular cataract extraction in nondiabetic patients. Protein-free extract, prepared by filtrating the water-soluble fraction of each nucleus through a centrifugal ultrafilter (molecular weight < 5,000), was analytically separated by high-performance liquid chromatography. RESULTS: No significant differences between non-brunescent and brunescent nuclei were observed in the concentrations (mean +/- SD) of 3-hydroxykynurenine O-beta-glucoside (0.67 +/- 0.38 vs. 0.85 +/- 0. 62 micromol/g wet weight), 4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-glucoside (4.1 x 10(5) +/- 2.9 x 10(5) vs. 6.3 x 10(5) +/- 5. 0 x 10(5) area unit/g wet weight), and kynurenine (0.016 +/- 0.011 vs. 0.029 +/- 0.021 micromol/g wet weight). A novel fluorophore that has not been identified so far was significantly present more in brunescent than in non-brunescent nuclei (brunescent: 1.5 x 10(5) +/- 1.0 x 10(5) vs. non-brunescent: 2.6 x 10(3) +/- 6.3 x 10(3) area unit/g wet weight, P <.01). Digestion of the protein-free extract with beta-glucosidase eliminated the peak corresponding to the novel unidentified fluorophore. CONCLUSION: The present results imply a novel protein-unbound fluorophore, presumably a beta-glucoside, might possibly be involved in brunescent cataract formation.

Aged↗