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Biomedical subjects

T Iwasawa

Publications and source records attributed to T Iwasawa.

At least 55 records · Page 3Linked to original sources

[High-resolution ultrasound of the thyroid in patients with Graves' disease].

The thyroid glands in 53 patients with Graves' disease were scanned with 10-MHz high-resolution ultrasound. Homogeneous echo pattern was noted in 21 patients (39.6%), and heterogeneous echo pattern was noted in 31 patients (60.4%). Each mean value of the serum triiodothyronine (T3), thyroxine (T4), and free thyroxine (Free T4) in patients with heterogeneous-echo thyroid was noted higher than that of the group with homogeneous-echo thyroid. (p less than 0.05) However, between the two groups, there is no significant difference in mean age and mean duration of treatment with antithyroid drugs. The heterogeneous echo pattern is strongly suggested to be correlated with the severity of hyperthyroidism.

Adolescent↗

[Consideration to the experimental study on the rapid palatal expansion in the rat].

The purpose of this study is to clarify the most suitable position and method to investigate bone formation in the mid-palatal suture after rapid palatal expansion in the rat. 10 of 8 week-old Wistar rats were employed to observe the structure of the normal mid-palatal suture at the line connecting the incisors, the anterior end of the anterior palatine foramen, the line bisecting the anterior palatine foramina, and the line of the 1st molars. A mid-palatal suture of 8 week-old Wistar rats was expanded laterally for 6 days by means of maxillary incisor expansion apparatus with a spring of 60 g load. After beheading, soft X-ray picture of the skull was taken to observe the suture. The maxilla was removed and decalcified sections (frontal section) were prepared. They were stained with hematoxylin and eosin for microscopy. The mid-palatal suture was observed at 4 levels to the lines drawn as follows; the line running through the centers of incisors (A), the line running the anterior ends of the anterior palatine foramen (B), the line running through the center of the anterior palatine foramen (C), and the line running through the centers of the 1st molars (D). At the opposing margins of A and B, the suture was composed of two layers; the layer of osteoblasts and the layer of interconnecting Sharpey's fibers. At C, the suture was curved and the layer of Sharpey's fibers were made up with longitudinal as well as transverse fibers.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

[Multiple cerebral venous angiomas associated with mixed pial and dural arteriovenous malformation].

Venous angioma is a relatively rare entity of vascular malformations of the brain and usually found as a solitary lesion. Cases of multiple lesions and/or coupled with other vascular malformations are extremely rare. We present the first case of multiple supratentorial venous angiomas associated with mixed pial and dural arteriovenous malformation (AVM) fed by the posterior cerebral artery, the occipital artery and the posterior meningeal artery.

Adolescent↗

[Experimental and clinical studies on amoxicillin sustained-release preparation in the otorhinolaryngologic field].

Fundamental and clinical evaluations of a new continual penicillin, C-AMOX, were performed. The results obtained were as follows. 1. Concentration in serum: The level of serum concentration after giving 500 mg of oral C-AMOX was determined in 3 cases of health adult. The maximal level measured 4.8 micrograms/ml at 4 hours after oral administration. Even 8 hours after oral administration, clinically effective serum C-AMOX concentration 1.6 micrograms/ml was still demonstrable. 2. Concentration of tissues: At 4 hours after a single oral dose of 500 mg, the concentration in the tissues of palatine tonsilla was 0.6 microgram/g as against 4.9 micrograms/ml in the serum, and the concentration in the tissues of mucous membrane of maxillary sinus was 0.5 microgram/g when measured 4.6 micrograms/ml in the serum. 3. Results of clinical treatment: C-AMOX of oral administration was tested in 46 cases of usually encountered acute an chronic infections in the otorhinolaryngologic field, the results being excellent in 25 cases, good in 14 cases and fair in 6 cases. When the excellent and good were bracketed together, it amounts to 39 cases (84.8%). It can be considered as high effective ratio. No side effect was shown with the oral administration of C-AMOX.

Adult↗