Search PubMed⌕ Search

Biomedical subjects

T Imaeda

Publications and source records attributed to T Imaeda.

At least 73 records · Page 4Linked to original sources
PubMed1989

Three-dimensional CT imaging for wrist disorders.

Three-dimensional CT imaging of the wrist was performed in 20 patients: three with Kienböck's disease, 14 with fractures or dislocations of the carpal bones, two with dislocation of the distal radio-ulnar joint and one with an intra-articular fracture of distal radius. These images were compared with those of plain radiographs and computed tomography. With the exception of two cases of distal radio-ulnar joint dislocation and one case of hamate body fracture, three-dimensional CT imaging was helpful in detecting the displacement of the fracture and in determining the location and the direction of the displaced carpal bone. Furthermore, the presence of small fragments could be observed more easily in the three-dimensional CT image. Three-dimensional CT imaging provides a great deal of information that cannot be obtained by conventional radiographs or CT images even at their present stage of technical development.

Adolescent↗
PubMed1989

[A case of hepatocellular carcinoma with a duodenal invasion from metastatic lymph node].

A 64-year-old male, who had been diagnosed as having hepatocellular carcinoma, was admitted to hospital and underwent transcatheter arterial infusion therapy. CT and US examinations revealed a large tumor with air in its center. Barium meal examination of the duodenum showed a large filling defect with a central excavation. At endoscopic examination, a dark reddish tumor was seen protruding into the duodenal lumen. A biopsy specimen from this tumor revealed a hepatocellular carcinoma. The patient subsequently died of hepatic coma following gastrointestinal bleeding. An autopsy revealed that metastatic lymph nodes had infiltrated into the adjacent duodenum. Nine previous cases of duodenal metastasis from a hepatocellular carcinoma have been reported in the Japanese literature.

Biopsy↗
PubMed1989

[A case of hepatocellular carcinoma (HCC) with a huge tumor thrombus in the right atrium].

A case of HCC with a huge tumor thrombus in the right atrium is reported. CT and celiac angiography revealed HCC in the liver. Inferior vena cavography and cardiac blood pool scintigraphy demonstrated a large defect in the right atrium, and 67Ga-citrate scintigraphy showed a lesion of abnormal accumulation in the right atrium. With these findings, diagnosis of HCC with a tumor thrombus in the right atrium was made, and the clinical diagnosis was confirmed by autopsy.

Carcinoma, Hepatocellular↗
PubMed1989

[A taxonomic study on a mycobacterium which caused a skin ulcer in a Japanese girl and resembled Mycobacterium ulcerans].

A taxonomic study has been made on a mycobacterial strain isolated from skin ulcer lesion of a 19 year-old Japanese girl who has lived only in Japan. By numerical classification, in which 108 characters were used, 6 isolates of this strain formed one cluster together with Mycobacterium ulcerans strains. However, the isolates were distinguished from the M. ulcerans strains, forming a subcluster. The isolates were differentiated by the characters shown in Table 2 from authentic M. ulcerans strains. The mycolic acids of the strain ATCC 33788 isolated from Japanese girl were distinguished from those of the type strain ATCC 19423 of M. ulcerans. The number of carbon atoms of alpha-mycolate of the former centered at 80, whereas those of the strain ATCC 19423 at 76. The number of carbon atoms of the alpha-unit was 24 in both strains and the number of double bonds was 2 in both strains. The strain ATCC 33788 showed a 100% similarity with the strain ATCC 19423 in DNA hybridization. In view of the above results, we have concluded that the strain belongs to a new subspecies of M. ulcerans (M. ulcerans subsp. shinshuense). Until now, M. ulcerans infection has occurred only in three area of the world, Africa, Oceania, and South and Middle America. Our case is the first case of M. ulcerans infection discovered in an area other than the above. However, the strain was not the same as the M. ulcerans described previously but differed from it in mycolic acids and some biological and biochemical characteristics.

Adult↗
PubMed1988

Effect of metal ions on the adaptive response induced by N-methyl-N-nitrosourea in Escherichia coli.

Induction of the adaptive response was quantified by analysis of beta-galactosidase released after the treatment of Escherichia coli CHS26/pYM3 (ada'-lacZ') with N-methyl-N-nitrosourea (MNU). Of the 15 metal ions examined, only Cd++ and Hg++ inhibited induction of the adaptive response with neither severe suppression of cell growth nor inhibition of the induction of the SOS response by MNU. Mutagenicity of MNU was potentiated by the presence of these metal ions in an E. coli strain. These results suggest that the inhibition mechanism involves a specific interaction of Cd++ or Hg++ with O6-methyl-guanine-DNA methyltransferase.

Cadmium↗
PubMed1986

A cooperative taxonomic study of mycobacteria isolated from armadillos infected with Mycobacterium leprae.

Seventeen strains of mycobacteria, recovered from six armadillos experimentally infected with Mycobacterium leprae, were examined in ten different laboratories. This collaborative study included use of conventional bacteriological tests, lipid analyses, determination of mycobactins and peptidoglycans, characterization by Py-MS, and immunological, metabolic, pathological and DNA studies. These armadillo-derived mycobacteria (ADM) formed five homogeneous groups (numbered ADM 1 to 5) on the basis of phenetic analyses. However, DNA studies revealed only four homogeneous groups since group ADM 1 and one of the two strains in group ADM 3 showed a high level of DNA relatedness. The phenetic and DNA studies confirmed that the ADM strains differed from all other known mycobacteria. Cultural, biochemical, metabolic and pathogenic properties as well as DNA-DNA hybridizations clearly differentiated these ADM from M. leprae.

Amino Acids↗
PubMed1986

Mycobacterium fortuitum subspecies acetamidolyticum, a new subspecies of Mycobacterium fortuitum.

Mycobacterium fortuitum subspecies acetamidolyticum is a new subspecies of M. fortuitum and has an intermediate growth rate. It is a nonphotochromogenic mycobacterium. It does not utilize glutamate but utilizes acetamide as a simultaneous nitrogen and carbon source. It is able to utilize acetate, malate, pyruvate, fumarate, glucose, fructose, and n-propanol as the sole sources of carbon in the presence of ammoniacal nitrogen, but does not utilize them in the presence of glutamate-nitrogen. It is easily differentiated from all rapidly growing mycobacteria by its inability to utilize glutamate as a simultaneous nitrogen and carbon source, and from all slowly growing mycobacteria by its capacity to utilize acetamide as a simultaneous nitrogen and carbon source. Its mycolic acid pattern is different from that of M. fortuitum. However, its deoxyribonucleic acid showed 94% relatedness with that of M. fortuitum. In view of the above findings, it has been designated as a new subspecies of M. fortuitum. The organism was isolated from sputum of a 56-year-old patient with lung disease and is considered to be a lung pathogen. The type strain is ATCC 35931 (NCH E11620).

Base Composition↗
PubMed1986

Electron microscopy of Mycobacterium leprae in cutaneous nerve components.

Cutaneous nerves in lepromatous lesions from ninety-six patients were observed by electron microscopy. The regenerative process of myelinated fibers was evident within lepromatous tissues. Intact or degenerative forms of Mycobacterium leprae were surrounded by the electron transparent substance within the axoplasm and Schwann cell cytoplasm. In contrast, the microenvironment of M. leprae in macrophages was characterized with fusing lysosomes and foamy structures. These results suggest that the electron transparent substance may be derived from bacterial metabolites and also that the foamy structure may originate from lysosomal substance.

Axons↗