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Biomedical subjects

T Ibrahim

Publications and source records attributed to T Ibrahim.

9 recordsLinked to original sources
PubMed1992

Quantitative analysis of ventricular late potentials (LP) in healthy subjects. Comparative study with Holter monitoring.

Signal averaging is a technique that improves the signal-to-noise ratio. It allows the detection of low-amplitude wave formes in the terminal portion of the QRS complex, also known as ventricular late potentials. A high incidence of arrhythmic events is found in patients with abnormal ventricular late potentials after an acute myocardial infarction. Few wide studies have been conducted in healthy subjects to assess normal values. One hundred sixty-five healthy subjects are enrolled in our study (59 men and 106 women). The results (mean +/- standard deviation) are as follows: duration of filtered QRS: 89.5 +/- 9.1 ms; duration of the low-amplitude signals in the terminal portion of QRS < 40 microV: 27.1 +/- 7.8 ms; root-mean-square voltage in the last 40 ms: 47.2 +/- 29.5 microV. A signal difference is noted between men and women for the QRS duration. No difference is found in HFD40 and RMS40. QRS duration confidence limits of 95% are < 108 ms for the total group. HFD40 and RMS40 confidence limits of 95% are respectively of 43 ms and 13 microV. There is no significant difference of the values for age. There is no relation between the severity of a ventricular arrhythmia and the values of the three parameters of the late potentials in a healthy subjects population.

Adult↗
PubMed1987

Detection of right atrial myxoma by Fourier phase analysis.

The usefulness of radionuclide imaging in the detection of cardiac tumors has been demonstrated previously in left atrial myxomas. We report a case of right sided myxoma successfully diagnosed by radionuclide imaging and evaluated by cine display, Fourier phase analysis and paradox image. These three techniques are now available in many computer programs for gated cardiac blood pool imaging and provide an additional tool for assessing cardiac tumors. Particularly, functional paradox and Fourier phase analysis seem promising tools in the detection of both left and right sided tumors.

Child↗
PubMed1987

Comparison of the immediate effects of two beta-blocking drugs: a nonselective and a cardioselective with modest ISA in exercise-induced angina.

To compare the effects of two beta-blocking drugs: a nonselective (propranolol) and a cardioselective with modest intrinsic sympathomimetic activity (visacor), 24 patients with stable angina pectoris performed a control exercise (without medication) on a bicycle ergometer (increments of 30 W every 3 min), and thereafter were randomized to receive either propranolol (40 mg t.i.d.) or visacor (200 mg once daily) for a 48-hour double-blind trial. The 2 groups on control exercise were similar with regard to their exercise tolerance: 7.6 +/- 2.3 versus 7.1 +/- 1.4 min (NS) and the behavior of heart rate, systolic, diastolic blood pressure and double product, at rest and during exercise. They exercised on the 2nd day 2 h after the intake of propranolol or visacor. In the 12 patients randomized to propranolol, heart rate, systolic and diastolic pressures, double product were significantly reduced at rest, compared with control exercise: 67 +/- 8 versus 81 +/- 10 beats/min (p less than 0.01), 132 +/- 20 versus 146 +/- 21 mm Hg (p less than 0.02), 80 +/- 8 versus 88 +/- 10 mm Hg (p less than 0.02), 8,828 +/- 1,927 versus 11,863 +/- 2,138 mm Hg X min-1 (p less than 0.001), respectively. On the contrary, in the 12 patients randomized to visacor, these parameters at rest were less modified and only heart rate was significantly decreased: 71 +/- 9 versus 81 +/- 11 beats/min (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Adrenergic beta-Antagonists↗
PubMed1986

[Effects of physical training on the denervated human heart after orthotopic cardiac transplantation].

Three patients who had undergone an orthotopic cardiac transplantation followed a course of supervised intermittent physical training (60 to 80 per cent of the maximum load) involving three weekly sessions of thirty minutes, for a period of 150 +/- 80 days. During maximal effort, we observed increases of 50 per cent in the load in watts (0.05 less than p less than 0.1), 40 per cent in oxygen consumption (0.1 less than p less than 0.2), 10 per cent in heart rate (p = 0.5) and 21 per cent in systolic blood pressure (0.7 less than p less than 0.8). The respiratory equivalent for oxygen decreased by 21 per cent (0.025 less than p less than 0.05) and the respiratory quotient by 5 per cent (0.4 less than p less than 0.05). For a given submaximal effort (30 watts) the following decreases were observed: 9 per cent in oxygen consumption (V'O2) (0.1 less than p less than 0.2), 32 per cent in the minute ventilation (V'E) (0.05 less than p less than 0.1), 22 per cent in the respiratory equivalent for oxygen (REO2) (0.025 less than p less than 0.05), 8 per cent in the respiratory quotient (RQ) (0.2 less than p less than 0.3) and 11 per cent in the heart rate (HR) (0.1 less than p less than 0.2). The systolic blood pressure (SBP) increased by 6 per cent (0.2 less than p less than 0.3). No changes were observed in these parameters in the postoperative follow-ups (10 to 24 months) of two patients who did not undergo physical training. Physical training is, therefore, necessary in the process of physical readaptation of patients after orthotopic cardiac grafts.

Adult↗
PubMed1984

Spiramycin and erythromycin in the treatment of acute tonsillo-pharyngitis: a comparative study.

A randomized study was carried out in 100 patients with acute tonsillo-pharyngitis to compare the effectiveness and tolerance of treatment with 500 mg spiramycin 3-times daily for 3 days and 500 mg erythromycin 3-times daily for 5 days. Details were recorded on entry of fever, sore throat, difficulty in swallowing, inflammation of the tonsils and/or pharynx, and oedema. Patients in the two groups were re-examined on Days 4 and 6, respectively. Throat swab cultures and blood determinations of haemoglobin, leucocytes and erythrocyte sedimentation rate were made before and after treatment. The results, analyzed in the 95 patients (48 on spiramycin, 47 on erythromycin) who attended for follow-up, indicated that whilst both antibiotics were effective, only 1 patient receiving spiramycin was classified as failing to respond to treatment compared with 8 of those receiving erythromycin. Moreover, significantly fewer patients on erythromycin had complete disappearance of all the signs and symptoms at the end of the treatment period. These findings were supported by the results of the bacteriological cultures. Both treatments reduced leucocyte levels in those patients with high counts initially, but there was no apparent effect on haemoglobin or erythrocyte sedimentation rate. Two patients on spiramycin complained of dry mouth. In the erythromycin group, 2 patients reported dizziness and 5 nausea.

Adolescent↗