Formation of IgE-binding factors by rat T lymphocytes. IV. Mechanisms for the formation of IgE-suppressive factors by antigen stimulation of BCG-primed spleen cells.
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T Huff
Publications and source records attributed to T Huff.
Type II interferon induction and passive transfer depress the murine cytochrome P-450 drug metabolism system.
Induction of type II interferon by sensitization of mice with Mycobacterium tuberculosis strain BCG and challenge with tuberculin resulted in a depression of the cytochrome P-450 drug metabolism system of the liver. The degree of depression was significantly greater than in mice that were only sensitized to BCG. Cytochrome b5 levels were not affected. In addition, the level of the depression of the cytochrome P-450 system correlated with the levels of type II interferon induced. Passive transfer of exogenous type II interferon preparations also significantly depressed the cytochrome P-450 system. Passive transfer of mock interferon or of normal serum had no effect.
Aminopyrine↗
7-Chloro-4,6-dimethoxy-1(3H)-isobenzofuranone and basidalin: antibiotic secondary metabolites from Leucoagaricus carneifolia Gillet (basidiomycetes) [corrected].
Two antibiotic metabolites were isolated from cultures of Leucoagaricus carneifolia. Their structures were elucidated by spectroscopic methods. The first compound, 7-chloro-4,6-dimethoxy-1(3H)-isobenzofuranone [corrected] (1) had to our knowledge not been described from natural sources whereas the second, basidalin (2), is a known metabolite of L. naucina (H. Iinuma et al., 1983). 1 exhibits antibiotic activities with minimal inhibitory concentrations of 20 micrograms/ml against Botrytis cinerea, the most sensitive microorganism.
Anti-Bacterial Agents↗