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Biomedical subjects

T Hosoki

Publications and source records attributed to T Hosoki.

33 records · Page 2Linked to original sources

Dynamic computed tomography of isodense hepatocellular carcinoma.

Dynamic computed tomography (CT) was performed on 11 patients with isodense hepatocellular carcinoma (hepatoma). Ten consecutive 3 s scans were performed within 30 s following the bolus injection of contrast medium. Except for the diffuse type, isodense hepatoma enhanced strongly in the arterial phase. The degree of enhancement declined in the portal phase. In the case of diffuse hepatoma, fine tumor nodules enhanced slightly, showing mottled patterns intermingled with low and high density areas in one patient. Time-density curves indicated that the tumor density increased rapidly in the arterial phase but decreased in the portal phase, approximating that of the surrounding liver. When CT is used as a screening method to detect hepatoma, the possibility of an isodense tumor should always be kept in mind. Dynamic CT is essential for the detection of isodense hepatoma as well as diffuse, small tumors. If simultaneous multilaminographic CT is available in the future, dynamic CT may be the best method to evaluate a suspected lesion.

Aged↗

Dynamic CT of pancreatic tumors.

Dynamic computed tomography was performed on 19 patients with clinically diagnosed pancreatic and peripancreatic tumors. There were 10 patients with pancreatic cancer, three with inflammatory pancreatic masses, two with cystadenoma, one with insulinoma, and three with peripancreatic tumors. Computed tomography was performed with a Varian-V-360-3 scanner; scanning was for 30 consecutive sec at 3 sec intervals after the bolus injection of 50 ml of contrast medium into the antecubital vein. Dynamic computed tomography (CT) may be more useful than conventional contrast CT because it facilitates: (1) correct evaluation of tumor vascularity allowing a differential diagnosis; (2) location of the boundary between tumor and a nontumor tissue; (3) detection of small tumors; and (4) visualization of pancreatic invasion by peripancreatic tumors. In addition, contrast enhancement and the degree of vascular proliferation can be quantitatively assessed by analyzing time-density curves.

Acute Disease↗

Dynamic computed tomography of hepatocellular carcinoma.

Nineteen patients with clinically proven hepatocellular carcinoma were studied by dynamic computed tomographic (CT) scanning. Ten consecutive 3 sec scans were performed within 30 sec, providing uninterrupted data collection. Dynamic CT scanning was useful in recognizing tumor vascularity, multiple small tumors, isodense tumors on conventional CT scans, the capsule of an encapsulated hepatocellular carcinoma, arteriovenous shunts, and vascular pools. Time-density curves were useful in evaluating the hemodynamics of the tumors; these could be classified into three types according to differences in their enhancement patterns.

Aged↗

Transcatheter arterial embolization for metastatic liver tumors: a study in resected cases.

We evaluated histologically the effect of transcatheter arterial embolization (TAE) in five metastatic liver tumors from gastrointestinal cancer, which were resected at surgery or removed at autopsy after TAE. TAE was carried out with cubes of gelatin sponge; in 2 cases, iodized oil was used as peripheral embolic material. Histological examination revealed three tumors to be completely necrotized. Approximately 80% of the remaining two tumors were necrotic. Our data suggest that TAE holds promise in the treatment of metastatic liver tumor from gastrointestinal cancer.

Adult↗

Use of meglumine iotroxate in the detection of liver tumors by computed tomography.

Experience with contrast enhanced computed tomographic (CT) examinations of 13 patients with hepatic tumors using a new cholangiographic contrast material, meglumine iotroxate, is described. After infusion, small density differences between the tumor and liver were accentuated. In 11 cases postcontrast CT using meglumine iotroxate improved visualization of lesions compared with conventional pre-and postcontrast CT using urographic contrast material. Our results indicate that contrast enhanced CT using meglumine iotroxate is a promising alternative to conventional CT in the detection of hepatic tumors.

Angiography↗