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Biomedical subjects

T Hosoi

Publications and source records attributed to T Hosoi.

At least 163 records · Page 9Linked to original sources
PubMed1985

[A case report of tubular adenoma of the breast].

Pure adenoma of the breast was seen in a 34-year-old Japanese woman. On examination, there was a firm, movable, nontender mass, 2.0 cm in diameter, in the upper outer quadrant of the left breast. The xeromammographic and macroscopical diagnosis was fibroadenoma. Histological examination, however, identified pure tubular adenoma of the breast. This was reported herein because of its extreme rarity.

Adenofibroma↗
PubMed1985

[Left ventricular diastolic properties in dilated cardiomyopathy, transmural myocardial infarction, and hypertrophic cardiomyopathy].

Left ventricular (LV) diastolic properties in dilated cardiomyopathy (DCM), transmural myocardial infarction (TMI), and hypertrophic cardiomyopathy (HCM) were evaluated. Radionuclide angiography and M-mode echocardiography were performed for 11 cases of DCM, 40 cases of TMI, 21 cases of HCM, and nine normal control subjects. In DCM, the peak filling rate (PFR) and filling fraction (FF) were significantly reduced, but the time to the peak filling rate (TPFR) was not prolonged. In TMI, both the PFR and FF were significantly reduced. Moreover, the TPFR was significantly prolonged in TMI as compared to DCM. Although depression of the PFR in HCM was not apparent, prolongation of the TPFR in HCM was marked. In DCM, there was good correlation between the PFR and left ventricular ejection fraction (EF) (r = 0.71, p less than 0.03). In TMI, there was a good correlation between the TPFR and the standard deviation of the LV phase angle histogram (SDP), indicating LV asynergy (r = 0.589, p less than 0.005). In HCM, both the FF and PFR correlated inversely with the LV wall thickness (r = -0.74, p less than 0.008; r = -0.581, p less than 0.03, respectively). These results indicate that various factors affect LV diastolic properties in heart disease, and that radionuclide angiography is a valuable technique for evaluating LV diastolic function.

Adolescent↗
PubMed1984

Detecting early esophageal cancers, with special reference to the intraepithelial stage.

Early-stage esophageal cancers, particularly intraepithelial cancers, are extremely difficult to detect because patients have no particular complaints and x-ray is so often useless. Only panendoscopic examination has proved highly effective in discerning lesions. Lugol-combined panendoscopic examination is not only feasible, but also effective in spotting the presence and spread of lesions.

Aged↗
PubMed1984

[Early detection of esophageal cancers, with special reference to the intraepithelial stage].

Panendoscopic examination, performed in 4,130 healthy males older than 50 years, detected 9 esophageal cancers (0.22%). Of these, 6 were classified as early esophageal cancer, and 3 of these 6 had intraepithelial cancers. In efforts to detect early esophageal cancers, especially at the intraepithelial cancer stage, panendoscopic examination seems to be highly useful.

Adult↗
PubMed1983

Monoclonal antibodies to hepatitis B surface antigen (HBsAg) as a tool for the automated HBsAg screening.

Hybridomas secreting monoclonal antibodies to hepatitis B surface antigen (HBsAg) were established by fusion of the spleen cells from mice immunized with purified HBsAg with the mouse myeloma cell line P3-NSI/1-Ag4-1. The monoclonal antibodies to the group-specific antigen (a) produced by one of them were used for the automated screening of HBsAg on the Groupamatic 360 (Kontron International). Its sensitivity is almost equal, but slightly inferior, to the system employing polyclonal horse antibodies to HBsAg; it barely detects 6 ng/ml of HBsAg. It is also as highly specific as the system with polyclonal antibodies; the incidence of false-positive reactions is 0.2%. These results indicate that the monoclonal antibodies will become a practical source for the HBsAg screening on the Groupamatic.

Animals↗