Hard tissue changes of the temporomandibular joint in an archaeo-osteological material from the 11th century.
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Biomedical subjects
Publications and source records attributed to T Hansson.
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The effects of cortisol on components of the liver microsomal mixed function oxidase system (MFO) of immature and starved rainbow trout, Salmo gairdnerii, Rich., were studied 3, 7 and 21 days after intraperitoneal implantation of cortisol-containing cholesterol pellets. The treatment resulted in significantly elevated NADPH cytochrome c reductase activities, concomitant with elevated plasma cortisol levels, at all sampling events, while no significant effects on either liver cytochrome P-450 or microsomal protein contents was observed. The cortisol-treated fish lost considerably more body weight than corresponding controls during the experimental period, while the effects on liver wet weight and liver somatic index were inconclusive.
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Out of 115 right temporomandibular joints from Swedish subjects aged 1 day to 93 years, 48 joints without any gross sign of arthrosis or deviation in form were examined histologically. The joint components were cut sagittaly, each into four parts. Histological sections were made of the condyle, the temporal component and of the articular disk. The total thickness of the soft tissue layers was measured in decalcified sections, cut from the medio-central and lateral parts of the condyle and the temporal component and from the medial, medio-central, latero-central and lateral regions of the disk. In the medio-central sections from the condyle and temporal component the thickness of the fibrous connective tissue layer i.e. the surface layer was also registered. The soft tissue layers were thickest in the condyle superiorly, about 0.4-0.5 mm, in the temporal component on the postero-inferior slope of the articular tubercle, about 0.5 mm, and in the disk posteriorly about 2.9 mm. In the roof of the fossa it was only 0.1 mm. The soft tissue layers on the condyle as well as the disk were thinner laterally while the corresponding tissue in the temporal component was thicker laterally. The thickness of the soft tissue layers seem to reflect the growth and functional load to which the joint is exposed.
The right TMJ from 115 individuals, aged 1 day--93 years, were examined macroscopically regarding the occurrence of deviation in form and arthrosis in the three articulating joint components. The changes were classified according to extent. In addition, the depth of the arthrotic lesions was determined. Nearly half (48 of 102) of the adult TMJs revealed some form of change. No changes in the joint surfaces were noted from individuals under 20 years of age. Deviations in form occurred in 45 of the 48 affected joints and arthrosis in 24. The deviations in form were most common in the condyle while arthrotic lesions were noted mainly in the disk and temporal component of the joint. The changes were usually local in nature and located in the lateral one-third of the joint.
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The right temporomandibular, sternoclavicular and first metatarsophalangeal joints were removed post mortem from 39 subjects. The surfaces of the various parts of the joints were examined and evaluated according to a grading system. Repeated evaluation of the joints showed a good reproducibility of the grading system. Of the 33 temporomandibular joints, 12 showed deviations in shape. Degenerative disease was uncommon and seen in only 3 joints. The total "score for degeneration" showed only a weak correlation with age (r = 0.28, rs = 0.08). Degenerative disease was common in the 35 sternoclavicular joints. All joints except 7 showed degenerative changes. A moderate correlation was found between age and the score for degeneration (r = 0.58). Of the 39 metatarsophalangeal joints only 5 were allotted no points of degeneration. A moderate correlation was found between age and score for degeneration (r = 0.61). No significant differences of degeneration were found between sexes. The coefficient of correlation between the score for degenerative disease of the temporomandibular joint and the degeneration score for the sternoclavicular joint and the toe-joint were r = 0.22 (rs = 0.16) and r = 0.46 (rs = 0.44), respectively. The significant association of degenerative disease found between the toe-joint and the sternoclavicular joint (r = 0.54, rs = 0.54) was reduced (to r = 0.29) when age-dependence was excluded. The degenerative changes described in this material are probably mostly due to local factors.
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The bone mineral content of 109 lumbar vertebrae from 36 different subjects was determined by dual photon absorptiometry. The mean age of the subjects was 58.5 years (range, 31 to 79 years). The ultimate strength of the vertebral bodies was determined during axial compression. Bone mineral content and ultimate compressive strength were correlated (r = 0.86) and the strength was found to increase linearly with increasing amounts of bone mineral content. No differences in this correlation were found in the four vertebral levels (L-4) included in the study, but a difference in this correlation was found between specimens taken from male and female subjects. The results make it possible to estimate the strength of a vertebral body from the knowledge of its bone mineral content as determined by dual photon absorptiometry and provide a basis of estimations of normal and abnormal amounts of bone mineral content in the vertebrae of the lumbar spine.
The bone mineral content of 109 excised lumbar vertebrae from 21 female subjects (aged 34 to 74 years) and 15 male subjects (aged 31 to 79 years) was determined with dual photon absorptiometry. It was correlated with the age, height, and weight of the subjects and with the body weight above each vertebra. No correlation was found between the bone mineral content and the lumbar spine score of Barnett and Nordin. The bone mineral content determined with dual photon absorptiometry was also correlated with the weight of fresh and ashed bone cubes removed from the interior of 40 of the aforementioned vertebrae selected at random. The bone mineral content decreased with increasing age and at a similar rate within the ages studied in both sexes. The findings indicated that pathologic demineralization in the elderly could be the result of low bone mineral content early in life, and more frequently so in female vertebrae.
The bone mineral content and the ultimate compressive strength were determined in 109 fresh lumbar vertebrae from 36 different subjects, 31 to 79 years of age. The degree of macroscopic disc degeneration and the types of fracture were determined. Three types of fracture-central, wedge and transverse-were found, but only under magnification and at simultaneous movements of the fracture segment. The central type of fracture was found predominantly in specimens with high bone mineral content surrounded by normal discs. The wedge type of fracture was consistent with lower bone mineral content and more severe disc degeneration.
The bone mineral content of 109 lumbar vertebrae was related to the number of trabecular microcalluses in the vertebral bodies. The appearance and location of the calluses were also investigated. Microcalluses were found in 87 of the vertebral bodies. The incidences of calluses varied in the different groups (31-79 years) between 60 and 90%. The number of calluses increased with decreasing bone mineral content. The location of the calluses corresponded to the location of experimental in vitro compression fractures of the vertebral bodies.
A new technique for determination of the bone mineral content in the vertebral body by means of a laterally directed roentgen ray beam is presented. By using a stable high voltage for the roentgen tube and a stable detector with very high energy resolution, the amount of bone mineral in the path of the radiation beam can be determined with correction for both fat and lean soft tissue. The results so far indicate that the technique is useful for objective determination of the bone mineral content in the vertebral body.
A miniaturized universal testing machine, HYOMEX, designed for biomechanically testing spinal structures of an anaesthetized research animal, such as a pig, is presented. A variety of mechanical applications such as static and dynamic tests, creep and relaxation tests, and fatigue tests with frequencies up to 20 Hz are possible. The system permits force control as well as displacement control. Continuous surveillance is made possible through interfacing the system to a computer. An application is presented where the viscoelastic behaviour in a porcine lumbar spine was measured.
Back injuries occurring during isometric strength testing motivated a statistical analysis to determine if a reduction in the number of exertions during the test was possible without profound influence upon the accuracy of the results. Strength measurements from more than 1,000 volunteers in an industrial back pain study were examined. It was concluded that one exertion in each test position for each subject provided a reasonably good indication of the subject's strength in that position, but strength in one position.