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T Hanamura

Publications and source records attributed to T Hanamura.

40 records · Page 3Linked to original sources

[Dimer-X ventriculography (author's transl)].

After the first report on ventriculography with a water-soluble contrast medium, Conray, by Campbell et al., many authors reported complications such as convulsion which are attributable to the irritating effect of this agent. On the other hand its value has been appriciated. Recently Gonsette recommended a new water-soluble contrast medium, meglumine iocarnate (Dimer-X), for ventriculography and reported that this new agent is less epileptogenic and less harmful. Because of these advantages, they have been performing ventriculography routinely with Dimer-X and recognized its usefulness. The only noticeable complication has been the transient elevation of body temperature in almost a half of the series. As far as our experience goes there is no case of convulsive seizure as complication. As compared to gas ventriculography, the fine details of dimension and configuration of the ventricles are far more beautifully delineated with the water-soluble contrast media.

Adult↗

Hemodynamics in and around the ischemic focus: a local angiographic study via catheterization to the middle cerebral artery of the cat.

Local hemodynamics in and around the ischemic focus following middle cerebral artery occlusion (MCA) were investigated on angiography by direct infusion of contrast material into the MCA. In anesthetized cats, a catheter was introduced just distal to the site of MCA occlusion through the transorbital approach. MCA stump pressure following occlusion was approximately 20 mmHg. Solute infusion with hydrostatic pressure exceeding stump pressure by approximately 20 mmHg was found to be sufficient to perfuse the entire territory of the MCA. Serial angiography revealed that cortical MCA branches were fully opacified first, and within 10 seconds disappeared centrifugally from the penumbral area. When vessels were occluded together with the internal carotid artery and anterior cerebral artery, backflow was delayed such that the contrast material remained longer within the ischemic focus. This new technique provides a sound basis not only for investigating local hemodynamics but also for direct pharmacological manipulation of the ischemic vessels and brain tissues.

Animals↗